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CDC recommends hepatitis C screening for all patients born from 1945-1965

Without other risk factors, all Americans born between 1945 and 1965 should have a one-time screening for the hepatitis C virus (HCV) according to new recommendations being published early online today in Annals of Internal Medicine, the flagship journal of the American College of Physicians. The Centers for Disease Control and Prevention (CDC) also recommends that all persons identified with HCV should receive a brief alcohol screening and intervention and be referred to appropriate care and treatment services for HCV and related conditions.

17 Aug 2012

Achieving AIDS-free generation worth more than Olympic gold

In this post in Huffington Post's "Healthy Living" blog, John-Manuel Andriote, a journalist and author living with HIV, asks, "For all of us living with HIV infection -- Oct. 27 will mark seven years since my own diagnosis -- the question we face daily, hopefully more consciously and deliberately than most, is how shall we live, knowing as we do that we will most assuredly die one day?"

16 Aug 2012

U.S. military medical team supports Botswana HIV prevention efforts

In an article on the U.S. Department of Defense webpage, the American Forces Press Service reports on how a U.S. military medical team is helping the Botswana Defense Force "to promote Botswana's national program of education, HIV screening and male circumcision surgeries to stem what's become a national epidemic," according to Army Col. Michael Kelly, an Army Reserve surgeon deployed in Botswana from the Army Reserve Medical Command in Washington.

16 Aug 2012

Gates looks to develop 'next-generation toilets' for developing world

Bill Gates, co-chair of the Bill & Melinda Gates Foundation, on Tuesday "announced the winners of the Reinvent the Toilet Challenge -- an effort to develop 'next-generation' toilets that will deliver safe and sustainable sanitation to the 2.5 billion people worldwide who don't have it," according to a foundation press release.

16 Aug 2012

Human milk oligosaccharides may reduce risk of mother-to-child HIV transmission

An international team of researchers has found that certain bioactive components found in human milk are associated with a reduced risk of HIV transmission from an HIV infected mother to her breast-fed infant. Their study will be published in the August 15 online edition of American Journal of Clinical Nutrition.

16 Aug 2012

Scientists researching Ebola virus say vaccine 'unlikely' due to funding restraints

"Scientists researching the lethal Ebola virus have told [BBC News] that a commercial vaccine to prevent the onset of infection may never be developed," the news service reports.

16 Aug 2012

India launches new laboratory for HIV vaccine research in collaboration with IAVI

India on Monday "opened a $12 million, government-backed laboratory whose mission is to create a new vaccine against HIV," Science Insider reports.

16 Aug 2012

Medicago, IDRI receive FDA approval to commence Phase 1 H5N1 vaccine trial

The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), announce that they have been cleared by the U.S. Food and Drug Administration (FDA) to initiate a Phase 1 clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.

16 Aug 2012

Special device provides evidence of how bloodstream infections begin

New research may help explain why hundreds of thousands of Americans a year get sick - and tens of thousands die - after bacteria get into their blood. It also suggests why some of those bloodstream infections resist treatment with even the most powerful antibiotics.

16 Aug 2012

Article describes novel technique to study interactions between HIV-1 and P. falciparum

The World Health Organization estimates that in 2011 there were 216 million cases of malaria and 34.2 million people living with HIV. These diseases particularly afflict sub-Saharan Africa, where large incidence of co-infection result in high mortality rates. Yet, in spite of this global pandemic, interactions between the parasite that causes malaria, Plasmodium falciparum, and HIV-1 are poorly understood.

16 Aug 2012

Researchers discover why people with sickle cell disease get milder cases of malaria

Researchers at Duke University Medical Center may finally have discovered why people with sickle cell disease get milder cases of malaria than individuals who have normal red blood cells.

16 Aug 2012

Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection

Genocea Biosciences announced today that it has initiated a Phase 1/2a clinical study with its lead candidate, GEN-003. GEN-003 is an investigational vaccine designed to stimulate T cell and B cell immune responses to potentially reduce the frequency and severity of clinical outbreaks associated with moderate-to-severe Herpes Simplex Virus type 2 (HSV-2) infection.

16 Aug 2012

Non-antibiotic compounds can prevent urinary tract infections

The latest episode in the American Chemical Society's (ACS') award-winning Global Challenges/Chemistry Solutions podcast series describes a potential new approach for treating urinary tract infections (UTIs) - which affect millions of people annually - without traditional antibiotics. Because it involves non-antibiotic compounds, the approach would not contribute to the growing problem of antibiotic-resistant bacteria, or "superbugs."

16 Aug 2012

CSIS report examines global polio eradication efforts

The Center for Strategic & International Studies (CSIS) on Monday released a report called "Eradicating Polio in Afghanistan and Pakistan." According to the report summary, efforts to eradicate the virus globally "have proved largely successful, in part thanks to the Global Polio Eradication Initiative (GPEI), launched by the international community in 1988," and "[t]he number of new cases has dropped in the past decade, even in countries where the virus has never been eradicated."

15 Aug 2012

Recognizing the role of international partnerships in global health

"When you're dealing with a global public health crisis, having an international presence isn't just advisable -- it is imperative," Margaret McGlynn, president and CEO of the International AIDS Vaccine Initiative (IAVI), writes in this post in USAID's "Impact" blog, adding, "That's why the [IAVI], in partnership with USAID, has worked diligently over the past several years to establish itself as a truly global non-profit partner."

15 Aug 2012

Universal HIV treatment, if achieved, would not mean eradication of AIDS

In this post in BMJ's "Yankee Doodling," Douglas Kamerow, chief scientist at RTI International and an associate editor for the journal, reflects on the possibility of achieving an AIDS-free generation "if somehow we succeeded in getting all HIV positive people in the world identified and under long term treatment."

15 Aug 2012

U.S. support of PEPFAR, Global Fund helping to achieve global AIDS, TB, malaria goals

In this post in Huffington Post's "Impact" blog, Deborah Derrick, president of Friends of the Global Fight Against AIDS, Tuberculosis (TB) and Malaria, examines "the success of U.S. efforts to promote better global health through support for [PEPFAR] and the Global Fund to Fight AIDS, Tuberculosis and Malaria."

15 Aug 2012

Overtreatment of malaria in central, south Asia leading to neglect of other diseases, study finds

"Over diagnosis and mistreatment of malaria in central and south Asia may be widespread, leading to the neglect of other serious illnesses, according to a new study from Afghanistan," published in the British Medical Journal last month, SciDev.Net reports.

15 Aug 2012

Catechins may help reduce neurological complications linked to HIV

Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications.

15 Aug 2012

Antisense therapy shows promise in treating toxoplasmosis

A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, it reduced the number of viable parasites by more than 90 percent, researchers from the University of Chicago Medicine report in the Proceedings of the National Academy of Sciences.

14 Aug 2012