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Researchers discover potential drug targets that might reduce ventilator-induced lung inflammation

When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.

19 Jul 2012

UNMC's ART injectables can successfully treat HIV infection

This has been a good week for breakthroughs in HIV/AIDS. Earlier this week, the Food and Drug Administration approved a daily pill, Truvada, which reduces the risk of HIV infection. Today, a University of Nebraska Medical Center research team's progress toward developing weekly or twice-monthly injectable antiretroviral therapy (ART) nanomedicines for patients with human immunodeficiency virus (HIV) infection will be highlighted as the cover story in the Journal of Infectious Diseases.

19 Jul 2012

AHF: U.S. defends Obama no-show at AIDS conference

On the heels of a White House defense of President Barack Obama's decision to skip the XIX International AIDS Conference in Washington D.C. (Agence France-Presse: "US defends Obama no-show at AIDS Conference," By Kerry Sheridan, July 18, 2012) AIDS Healthcare Foundation (AHF) released a TV ad featuring Archbishop Desmond Tutu of South Africa warning of the consequences of a "global abandonment of AIDS."

19 Jul 2012

AOA honors Medical College of Georgia student with Kuckein Fellowship

A student at the Medical College of Georgia at Georgia Health Sciences University is among 47 recipients of the 2012 Carolyn L. Kuckein Student Research Fellowship from the national medical honor society Alpha Omega Alpha.

19 Jul 2012

Bryologs more potent than prostratin in treating HIV

Thanks to antiretrovirals, an AIDS diagnosis hasn't been a death sentence for nearly two decades. But highly active antiretroviral therapy, or HAART, is also not a cure.

19 Jul 2012

USA Today examines recent HIV breakthroughs

USA Today examines several scientific breakthroughs that researchers say "could be key to reducing new HIV infections." "Doctors are hopeful not because of a single discovery, but because of a string of breakthroughs over the past two or three years, says Diane Havlir, a professor at the University of California-San Francisco," the news service writes.

19 Jul 2012

PATH Blog highlights efforts to reduce HIV in DRC

The PATH Blog reports on the organization's efforts in the Democratic Republic of Congo (DRC) "to reduce transmission of HIV, deliver integrated care and services for people affected by HIV/AIDS, and build up the country's health system to expand and improve services."

19 Jul 2012

Better methods needed to diagnose and treat HIV, TB in children

Jennifer Furin, an infectious diseases physician and medical anthropologist who specializes in the management of tuberculosis (TB) and HIV in resource-poor settings, writes in a post in the Bill & Melinda Gates Foundation's "Impatient Optimists" blog that "when it comes to the great advancements made in global HIV and TB care, children are being left behind."

19 Jul 2012

Duke-led consortium to focus on inducing neutralizing antibodies for HIV-1 prevention

Two Los Alamos National Laboratory scientists are among the team recently funded to explore ways to create the precise immune factors needed for effective vaccines against HIV.

19 Jul 2012

NPR reports on Brazilian clinical trial of Truvada as prevention strategy

NPR's "Shots" blog reports on one of the drug trials considered by the FDA in its approval of the antiretroviral drug Truvada for pre-exposure prophylaxis (PrEP) to prevent HIV among people at risk of contracting the virus, which "was done at the Oswaldo Cruz Foundation Research Institute, also known as Fiocruz, in Rio de Janeiro."

19 Jul 2012

Targets reached in Haiti's pilot cholera vaccination program, NPR reports

NPR's "Shots" blog reports on the results of a "high-visibility pilot project to vaccinate 100,000 Haitians against cholera." The blog writes, "Almost 90 percent of the target population -- half in Port-au-Prince and the other half in a remote rural area -- got fully protected against cholera, meaning they got two doses of the oral vaccine."

19 Jul 2012

Africa's new partnership for sustainable health development 'makes sense'

With Africa's "emerging position in the global order, ... astute African leaders are striving to ensure that this realignment delivers a new paradigm of partnership for sustainable health development -- a partnership that is led by Africa, for Africans, through African-sourced solutions," UNAIDS Executive Director Michel Sidibe writes in a Huffington Post "Impact Blog" opinion piece.

19 Jul 2012

Study gauges depression among spouses of severe-sepsis survivors

Severe sepsis, a body's dangerous defensive response against an infection, not only diminishes the quality of life for patients - it puts their spouses at a greater risk of depression, a joint University of Michigan Health System and University of Washington School of Medicine study shows.

19 Jul 2012

Clinical trial to evaluate maraviroc-based PrEP regimens for HIV prevention

Scientists are launching the first clinical trial to test whether drug regimens containing maraviroc, a medication currently approved to treat HIV infection, are also safe and tolerable when taken once daily by HIV-uninfected individuals at increased risk for acquiring HIV infection. The eventual goal is to see if the drug regimens can reduce the risk of infection.

19 Jul 2012

Blog examines potential repercussions of CIA's fake vaccination campaign in Pakistan

In this post on her blog, "The Garrett Update," Laurie Garrett, senior fellow for global health at the Council on Foreign Relations (CFR), examines the potential implications of a fake hepatitis vaccine campaign carried out by the CIA in Pakistan last year in an attempt to gather DNA from Osama bin Laden's family.

19 Jul 2012

Alcohol and marijuana use predict hookah initiation, frequency

Nearly a quarter of college women try smoking tobacco with a hookah, or water pipe, for the first time during their freshman year, according to new research from The Miriam Hospital's Center for Behavioral and Preventive Medicine.

19 Jul 2012

Two polio campaign workers shot, wounded in Pakistan; WHO says no sign attack was deliberate

"Gunmen in Pakistan shot and wounded a staff member of the World Health Organization (WHO) and an expatriate consultant working for the United Nations health agency on Tuesday, the WHO said," Reuters reports.

19 Jul 2012

Report shows high rates of HIV infections and deaths from AIDS among Black MSM

Today, the Black AIDS Institute released its latest report, Back of the Line: The State of AIDS Among Black Gay Men in America. The landmark report highlights alarming data that show disproportionately high rates of HIV infections and deaths from AIDS among Black MSM, why the disparities persist and are growing worse, and the urgent need for local and national leadership to immediately address the devastating health crisis.

19 Jul 2012

Abscisic acid has anti-inflammatory effects in the lungs and gut

Building on previous work with the botanical abscisic acida, researchers in the Nutritional Immunology and Molecular Medicine Laboratory (NIMML) have discovered that abscisic acid has anti-inflammatory effects in the lungs as well as in the gut.

19 Jul 2012

Duke receives Gates Foundation grant for HIV vaccine study

The Bill & Melinda Gates Foundation has awarded a new grant to Duke University Medical Center for work developing vaccines that can induce IgA antibodies for preventing HIV-1 infection. This award comes from the Gates' Collaboration for AIDS Vaccine Discovery (CAVD) program.

19 Jul 2012