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Patients with community-onset CDI have increased risk of colectomy

Patients whose symptoms of Clostridium difficile infection (CDI) start outside of the hospital setting have a higher risk of colectomy due to severe infection, according to a large multicenter study funded by the Centers for Disease Control and Prevention (CDC) and published in Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

5 Apr 2012

Scripps Florida scientists to create new screening tests for HCV treatment discovery

Scientists from the Florida campus of The Scripps Research Institute have been awarded just over $1 million from the National Institutes of Health for a three-year study to develop new high-throughput screening tests to find compounds that disable a protein essential to hepatitis C virus (HCV) replication.

5 Apr 2012

Ventria completes VEN100 phase 2 trial on antibiotic-associated diarrhea

Ventria Bioscience has announced the successful completion of a phase 2 clinical trial of its lead therapeutic candidate, VEN100. The study was conducted by a team of investigators from the Department of Epidemiology, Division of Infectious Diseases, and Division of Geriatric Medicine at Johns Hopkins University.

5 Apr 2012

Trends in diagnostic coding may explain the cause of decline in pneumonia hospitalizations

Although data indicate that between 2003-2009 there was a substantial decline in the U.S. in hospitalizations for pneumonia and inpatient deaths, analysis suggests that trends in documentation and diagnostic coding, rather than improvements in actual outcomes, may explain much of the observed changes, according to a study in the April 4 issue of JAMA.

4 Apr 2012

Haitian cholera epidemic no place for 'good-guy/bad-guy distinctions'

In this Reuters opinion piece, finance blogger Felix Salmon responds to a New York Times (NYT) article published on Monday in which journalist Deborah Sontag examines the global response to Haiti's cholera epidemic.

4 Apr 2012

Advocates for Youth report examines youth policies within PEPFAR

A new report from Advocates for Youth "analyzes youth policies within the President's Emergency Plan for AIDS Relief (PEPFAR), including its legislative authority, most recent five-year strategy, relevant guidance documents, and all 21 currently available PEPFAR country Partnership Frameworks."

4 Apr 2012

Nuvilex realizes important role for Cell-in-a-Box technology

Nuvilex, Inc., an emerging biotechnology provider of cell and gene therapy solutions through acquisition of SG Austria assets, realizes the important role for Cell-in-a-Box technology and aims to bring to light its use in the production of therapeutic antibodies for clinically important diseases.

4 Apr 2012

New initiative aims to strengthen regulatory capacity, systems for delivery of medicines in Africa

"The need to ensure that people in Africa have access to essential, high quality, safe and affordable medicines has just received a major boost with the launch of the East African Community (EAC) Medicines Registration Harmonization Project in Arusha, Tanzania, on 30 March 2011," UNAIDS reports in a feature story on its website.

4 Apr 2012

MedImmune's quadrivalent flu vaccine may protect children

An intranasal vaccine that includes four weakened strains of influenza could do a better job in protecting children from the flu than current vaccines, Saint Louis University research shows.

4 Apr 2012

Discussion of NSABB recommendation to publish controversial bird flu studies to continue in London meeting

The National Science Advisory Board for Biosecurity's (NSABB) "reversal on publishing two controversial H5N1 studies is poised to shift discussions on the topic that continue in London this week, as more participants in the debate weigh in following the March 30 announcement," CIDRAP News reports.

4 Apr 2012

Scientists discover new anti-HCV antibodies

A team led by scientists at The Scripps Research Institute has found antibodies that can prevent infection from widely differing strains of hepatitis C virus (HCV) in cell culture and animal models.

4 Apr 2012

SFU receives NIH grant to develop effective HIV/AIDS vaccine

Jamie Scott, a Simon Fraser University professor and Canada Research Chair in molecular immunity, and three international collaborators are getting a hefty financial boost in their efforts to develop an effective HIV/AIDS vaccine.

4 Apr 2012

Infections in older adults may increase risk of hospitalization for dangerous blood clots

Research shows older adults who get infections of any kind - such as urinary, skin, or respiratory tract infections - are nearly three times more likely to be hospitalized for a dangerous blood clot in their deep veins or lungs, University of Michigan Health System research shows.

4 Apr 2012

Young girls face increased risk of side effects after Gardasil vaccination

Younger girls are more likely than adult women to report side effects after receiving Gardasil, the human papillomavirus vaccine.

4 Apr 2012

Hepatitis B-infected patients with longer telomeres more likely to develop HCC

Hepatitis B-infected patients with significantly longer telomeres—the caps on the end of chromosomes that protect our genetic data— were found to have an increased risk of getting liver cancer compared to those with shorter ones, according to findings presented by researchers at Jefferson's Kimmel Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2012.

4 Apr 2012

InstantLabs receives PTM certification for Salmonella Species Food Safety Kit

InstantLabs Medical Diagnostics Corporation, developer of the portable Hunter Accelerated Real-Time PCR system, today announced that its Salmonella Species Food Safety Kit has been certified as Performance-Tested Methods (PTM) No. 031202 by the AOAC Research Institute.

3 Apr 2012

South Sudan hoping to mark three years without recording polio case

"South Sudan officials are hopeful the country will soon be declared polio-free," if the nation can go another four months without recording a polio case, VOA News reports. "Before 2008, the area that is now South Sudan had been considered free of polio," but "that year the country was re-infected through an imported strain that originated in Nigeria," the news service writes.

3 Apr 2012

NSABB recommends full publication of controversial bird flu studies

The National Science Advisory Board for Biosecurity (NSABB) on Friday recommended that revised versions of two controversial studies on H5N1 avian flu be published in scientific journals, reversing its previous recommendation that the studies only be published if certain details were withheld, the New York Times reports.

3 Apr 2012

PRI's 'The World' examines role of churches in fight against HIV in Swaziland

PRI's "The World" examines the role of churches in the fight against HIV in Swaziland. The news service highlights several church-run HIV programs, writing, "Churches have long played an important role in caring for the sick, but in terms of HIV prevention they've been at odds with the public health community. It has often come down to one issue: until recently, Swazi church leaders publicly rejected the use of condoms by their congregants. But now you hear many comments that suggest a change in thinking."

3 Apr 2012

April issue of WHO Bulletin available online

The April issue of the WHO Bulletin features an editorial on the WHO research agenda for influenza; a public health round-up; an article on influenza in Ghana; a research paper on population-based burden of influenza-associated hospitalization in rural western Kenya; and a policy paper on the integration of pneumonia prevention and treatment interventions with immunization services in resource-poor countries.

3 Apr 2012