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Study examines TB services in prisons in countries receiving Global Fund grants

According to a study recently published in a special supplement of the Journal of Infectious Diseases, half of countries receiving grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria provide tuberculosis (TB) services in prisons; "even when TB services were provided to prisoners, they were limited in scope; and "few of the programs receiving a grant from the Global Fund offered services dedicated to the treatment and prevention of multi-drug resistant TB (MDR-TB)," an aidsmap news story reports.

31 Mar 2012

U.S. releases policy requiring dual-use biological research reviews amid bird flu debate

"The U.S. government on Thursday released a new policy that will require federal agencies to systematically review the potential risks associated with federally funded studies involving 15 'high consequence' pathogens and toxins, including the H5N1 avian influenza virus," Science Insider reports.

31 Mar 2012

'Large-scale action' needed in Myanmar to prevent spread of artemisinin-resistant malaria parasites

In this New York Times opinion piece, Frank Smithuis, director of Medical Action Myanmar in Yangon, and Nick White, professor of tropical medicine at the Mahidol Oxford Tropical Medicine Research Unit in Bangkok, recount a brief history of the development of anti-malaria drugs and their contribution to "a significant global reduction in malaria" and note that this progress "is now threatened by the emergence of malaria parasites that are resistant to artemisinin on the Cambodia-Thailand border ..., the same place where chloroquine resistance emerged 50 years ago and spread across Asia and Africa to claim millions of lives."

31 Mar 2012

Dengue infection makes mosquito's blood feeding more efficient

Mosquitoes infected with dengue virus experience an array of changes in the activity of genes and associated functions of their salivary glands, and these changes may lead to increased virus transmission, according to a recent study led by George Dimopoulos, Ph.D., of the Malaria Research Institute and Bloomberg School of Public Health at Johns Hopkins University.

31 Mar 2012

Data from Cempra's CEM-101 Phase 2 trial on N. gonorrhoeae infections to be presented at ECCMID

Cempra Inc., a clinical-stage pharmaceutical company focused on developing antibiotics to meet critical medical needs in the treatment of bacterial infectious diseases, today announced that data will be presented at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) demonstrating that CEM-101 (solithromycin) is active against antibiotic-resistant strains of N. gonorrhoeae.

31 Mar 2012

Data from Cempra's CEM-101 Phase 2 trial on CABP to be presented at ECCMID

Cempra Inc., a clinical-stage pharmaceutical company focused on developing antibiotics to meet critical medical needs in the treatment of bacterial infectious diseases,today announced that data will be presented at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), in London, March 31 to April 3,demonstrating CEM-101's (solithromycin's) efficacy to be comparable to levofloxacin in a Phase 2 trial of patients with community-acquired bacterial infections.

31 Mar 2012

Abbott receives CE Marking for PLEX-ID instrument and assays

Abbott announced today it has obtained CE Marking (Conformite Europeene) in the European Union to market its rapid, high-throughput PLEX-ID instrument, along with three assays for use on the system: PLEX-ID Viral IC Spectrum, PLEX-ID BAC Spectrum BC and PLEX-ID Flu.

31 Mar 2012

FDA approves Roche's cobas p 630 pre-analytical instrument

Roche announced today the FDA approval of a new pre-analytical instrument that provides an integrated primary tube handling solution for its widely adopted automated molecular testing platform.

31 Mar 2012

Cancer patients with CDI may benefit from DIFICLIR drug

New data presented at the 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) demonstrate that in cancer patients with CDI, DIFICLIR(fidaxomicin) may offer significant benefits in terms of clinical cure, recurrence and sustained clinical cure.

31 Mar 2012

IPS reports on research study examining knowledge, beliefs of cervical cancer among Argentinian women

Inter Press Service reports on a research study conducted in Argentina that "explored women's knowledge and beliefs about cervical cancer, in the provinces with the highest mortality from this highly preventable form of cancer, to design more effective policies."

31 Mar 2012

Risk of botulism at California fish processing company

The U.S. Food and Drug Administration, in a complaint filed by the Department of Justice, is seeking to stop the processing and distribution of fish products at a California company because of a risk of botulism and other food hazards.

30 Mar 2012

Stop TB Partnership, TAG release report on tuberculosis research funding

The Center for Global Health Policy's "Science Speaks" blog reports the findings from the second edition of the 2011 Report on Tuberculosis (TB) Research Funding and Trends from 2005-2010, released Thursday by Treatment Action Group (TAG) and the Stop TB Partnership.

30 Mar 2012

Infection with dengue virus turns on feeding-related genes in mosquitoes

Researchers at the Johns Hopkins Bloomberg School of Public Health have, for the first time, shown that infection with dengue virus turns on mosquito genes that makes them hungrier and better feeders, and therefore possibly more likely to spread the disease to humans.

30 Mar 2012

Basidiobolomycosis appears to be emerging in the Southwestern U.S.

An emerging fungal infection of the gastrointestinal tract that mimics cancer and inflammatory bowel disease appears to be emerging in the Southwestern United States and other desert regions, according to Mayo Clinic researchers in Arizona investigating the disease. The invasive fungus, Basidiobolus ranarum, is typically found in the soil, decaying organic matter and the gastrointestinal tracts of fish, reptiles, amphibians, and bats.

30 Mar 2012

Researchers, experts debate publication of H5N1 research amid updated studies

"As researchers from both sides of the debate over two controversial H5N1 studies weighed in Tuesday on full publication versus a more cautionary approach, two U.S. journals" -- the Journal of Infectious Diseases (JID) and its sister publication, Clinical Infectious Diseases -- "said they are developing policies to address any future such instances," CIDRAP News writes.

30 Mar 2012

Small electrical sensors can quickly detect MRSA infection

A simple test to identify MRSA in wounds could identify the superbug quickly and help prevent infection from spreading.

30 Mar 2012

Scientific research is crucial to preventing, controlling, eradicating infectious diseases

The debate about two studies showing that, with few genetic mutations, H5N1 bird flu strains could become more easily transmissible among ferrets, a laboratory model for humans, "has become a debate about the role of science in society.

30 Mar 2012

Health workers feeling effects of staff, supply shortages at clinics in southwestern Uganda

Health workers with Medical Teams International, a medical non-governmental organization, "say they are overwhelmed" by high demand at five health clinics in two southwestern Ugandan refugee centers, PlusNews reports.

30 Mar 2012

Treatment areas of ambulances fared well when tested for dangerous bacteria

Treatment areas of ambulances fared well when tested for dangerous bacteria, according to a new study published in the April issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

30 Mar 2012

Women with HIV superinfection have more potent antibody responses

Women who have been infected by two different strains of HIV from two different sexual partners - a condition known as HIV superinfection - have more potent antibody responses that block the replication of the virus compared to women who've only been infected once. These findings, by researchers at Fred Hutchinson Cancer Research Center in Seattle, are published online March 29 in PLoS Pathogens.

30 Mar 2012