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Study identifies new hypervariable regions in human gut viruses

A growing body of evidence underscores the importance of human gut bacteria in modulating human health, metabolism, and disease. Yet bacteria are only part of the story. Viruses that infect those bacteria also shape who we are. Frederic D. Bushman, PhD, professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, led a study published this month in the Proceedings of the National Academy of Sciences that sequenced the DNA of viruses -- the virome -- present in the gut of healthy people.

20 Mar 2012

Infection preventionists, healthcare epidemiologists play key roles in promoting antimicrobial stewardship

Infection preventionists and healthcare epidemiologists play key roles in promoting effective antimicrobial stewardship in collaboration with other health professionals, according to a joint position paper published today by the Association for Professionals in Infection Control and Epidemiology (APIC) and the Society for Healthcare Epidemiology of America (SHEA) in their respective peer-review journals, the American Journal of Infection Control and Infection Control and Hospital Epidemiology.

20 Mar 2012

AIDS survey preliminary data show stagnation in Uganda's HIV prevalence, need for improved prevention strategies, experts say

A preliminary report on the Uganda AIDS Indicator Survey, conducted by the Ministry of Health, shows the country's "HIV prevalence rate has stagnated over the last 10 years, and the number of people infected with HIV has risen from 1.8 million people to 2.3 million today," the Observer writes.

20 Mar 2012

TB Alliance launches new combination drug trial

In an ambitious effort to stem the dangerous tide of tuberculosis (TB) and deadly drug-resistant TB around the world, TB Alliance today announced that it has launched a first-of-its-kind clinical trial to test a novel drug combination – in both patients who have TB and those who have multidrug-resistant TB (MDR-TB).

19 Mar 2012

Common infections could become deadly with increase in antibiotic resistance, WHO's Chan says

As more bacteria become resistant to antibiotics, "common infections could become deadly, according to" WHO Director-General Margaret Chan, who spoke on Wednesday at a conference titled "Combating Antimicrobial Resistance: Time for Action" in Copenhagen, ABC News reports.

19 Mar 2012

First international podoconiosis initiative launched

The Global Network for Neglected Tropical Diseases' "End the Neglect" blog highlights "the first-ever international podoconiosis initiative, Footwork," launched on March 15.

19 Mar 2012

PaxVax announces FDA acceptance of IND for PXVX-0200 cholera vaccine

PaxVax Corporation, developer of innovative and socially responsible oral vaccines against infectious diseases, announced that the U.S. Food and Drug Administration (FDA) has accepted its investigational new drug (IND) application for its single-dose oral cholera vaccine, clearing the way to begin clinical trials. The company intends to begin Phase 3 trials later this year.

19 Mar 2012

Tiny Tim may have suffered from rickets and TB

Le Bonheur Professor Russell Chesney, M.D. believes he knows what was ailing Tiny Tim, the iconic character from Charles Dickens' "A Christmas Carol." Based on detailed descriptions of both the symptoms and living conditions of 18th century London, Dr. Chesney hypothesizes that Tiny Tim suffered from a combination of rickets and tuberculosis (TB).

17 Mar 2012

New EU project to assess risk of contaminated food brought in from other countries

The EHEC crisis in Germany in 2011 proved that food brought in from other countries can potentially carry agents that cause life-threatening diseases. Nevertheless, there have been extremely few investigations of the actual danger posed by germs that enter the EU along with food. The gap is now to be addressed by a new project, with the EU providing almost three million Euro to cover the costs.

17 Mar 2012

Greater Than AIDS, SiriusXM OutQ to launch SpeakOUT

SiriusXM OutQ, the nation's first and only 24/7 LGBT radio channel, and Greater Than AIDS, a national movement to respond to AIDS in America, announced today the launch of SpeakOUT: Real Talk about AIDS in Gay America, a limited-run series of live, call-in shows that will connect listeners across the country with medical experts, people living with HIV and notable members of the LGBT community to have an honest and challenging dialogue about the current state of the HIV/AIDS epidemic in the gay community as well as the country at large.

17 Mar 2012

U.S. Global AIDS Coordinator discusses AIDS 2012 conference

"For the first time in over 20 years, the biennial International AIDS Conference will be hosted on American soil," U.S. Global AIDS Coordinator Ambassador Eric Goosby writes in this post in the AIDS.gov blog.

17 Mar 2012

Partnerships critical to stopping HIV/AIDS, GBV among women

"For the past two weeks, the buzz in Washington, D.C., and at the White House is all about women and girls," Roxana Rogers, director of the USAID Office of HIV/AIDS, writes in this "IMPACTblog" post. She highlights a recently announced initiative, funded through PEPFAR, "to help local communities and grassroots organizations fight HIV/AIDS and gender-based violence.

17 Mar 2012

People of faith can work together to make water safe worldwide

"We don't honor God when 4,500 children die every day -- but they do -- from the lack of something so simple, each of us takes it for granted: a safe glass of water," Rabbi Jack Bemporad, executive director of the Center for Interreligious Understanding, and journalist Susan Barnett write in Huffington Post's "Religion" blog.

17 Mar 2012

Cuts to health budget lead to increases in HIV/AIDS, malaria, TB incidence in Greece

"The savage cuts to Greece's health service budget have led to a sharp rise in HIV/AIDS and malaria in the beleaguered nation, said a leading aid organization on Thursday," the Guardian's "News Blog" reports.

17 Mar 2012

Zimbabwe's plan to conduct household HIV testing raises concerns among some advocates

PlusNews examines the challenges and concerns surrounding Zimbabwe's plan to conduct a door-to-door HIV testing campaign, which has not yet begun but "is already being met with skepticism by activists who feel this is not a priority for the country, especially with global HIV/AIDS funding on the decline."

17 Mar 2012

World Bank report urges African governments, development aid donors to increase HIV prevention efforts

"With much of the global economy facing slowing growth and uncertain prospects, especially in developed countries, a new World Bank report" -- titled "The Fiscal Dimension of HIV/AIDS in Botswana, South Africa, Swaziland, and Uganda" -- "urges African governments and their development aid donors to do significantly more to prevent new HIV infections" and "warns that current spending on HIV/AIDS relates to past infections and is a potentially misleading indicator of the long-term public cost of the fight against HIV/AIDS," a World Bank press release states.

17 Mar 2012

The northeastern U.S. should prepare for a surge in Lyme disease this spring

The northeastern U.S. should prepare for a surge in Lyme disease this spring. And we can blame fluctuations in acorns and mouse populations, not the mild winter. So reports Dr. Richard S. Ostfeld, a disease ecologist at the Cary Institute of Ecosystem Studies in Millbrook, NY.

17 Mar 2012

Researchers describe preparation of chitosan nanoparticles

Nanoparticles containing chitosan have been shown to have effective antimicrobial activity against Staphylococcus saprophyticus and Escherichia coli. The materials could be used as a protective wound-healing material to avoid opportunistic infection as well as working to facilitate wound healing.

17 Mar 2012

Only 21 states require public reporting of hospital data on surgical site infections

Only 21 states require public reporting of hospital data on surgical site infections and, even when disclosure is mandated, the information is often not easily accessible to patients who could use it to make decisions about their medical care, according to new Johns Hopkins research.

17 Mar 2012

Deletion of Hms1 protein inhibits Candida albicans infection

Scientists at the University of Toronto have found a molecular mechanism that plays a key role in the transition of Candida albicans yeast into disease-causing fungus-one of the leading causes of hospital-acquired infection.

17 Mar 2012

Disease/Infection News

Study identifies new hypervariable regions in human gut viruses

Infection preventionists, healthcare epidemiologists play key roles in promoting antimicrobial stewardship

AIDS survey preliminary data show stagnation in Uganda's HIV prevalence, need for improved prevention strategies, experts say

TB Alliance launches new combination drug trial

Common infections could become deadly with increase in antibiotic resistance, WHO's Chan says

First international podoconiosis initiative launched

PaxVax announces FDA acceptance of IND for PXVX-0200 cholera vaccine

Tiny Tim may have suffered from rickets and TB

New EU project to assess risk of contaminated food brought in from other countries

Greater Than AIDS, SiriusXM OutQ to launch SpeakOUT

U.S. Global AIDS Coordinator discusses AIDS 2012 conference

Partnerships critical to stopping HIV/AIDS, GBV among women

People of faith can work together to make water safe worldwide

Cuts to health budget lead to increases in HIV/AIDS, malaria, TB incidence in Greece

Zimbabwe's plan to conduct household HIV testing raises concerns among some advocates

World Bank report urges African governments, development aid donors to increase HIV prevention efforts

The northeastern U.S. should prepare for a surge in Lyme disease this spring

Researchers describe preparation of chitosan nanoparticles

Only 21 states require public reporting of hospital data on surgical site infections

Deletion of Hms1 protein inhibits Candida albicans infection

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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