Disease/Infection News

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World Bank, WHO, UNAIDS report offers comprehensive look at HIV/AIDS in Middle East, N. Africa

The World Bank, WHO and UNAIDS on Monday released a joint report that pulls together data characterizing the HIV/AIDS epidemic from 23 countries in the Middle East and North Africa region, IRIN reports (6/30).

1 Jul 2010

Gen-Probe's APTIMA Trichomonas assay receives European CE mark

Gen-Probe Incorporated announced today that it has received a European CE mark for its APTIMA® assay for Trichomonas vaginalis, a common parasitic sexually transmitted disease.

1 Jul 2010

Cubist commences enrollment in Phase 2 study of CXA-201 for complicated intra-abdominal infections

Cubist Pharmaceuticals, Inc., a leading acute care therapeutics company, today announced the enrollment of the first patient in a Phase 2 study with CXA-201. This multicenter, double-blind, randomized, study will compare the safety and efficacy of intravenous CXA-201 with an active comparator in patients with complicated intra-abdominal Infections (cIAI). This international study is expected to enroll 120 patients.

1 Jul 2010

Prasco commences shipments of generic prescription ZEGERID Capsules

Santarus, Inc., a specialty biopharmaceutical company, today announced that pursuant to its distribution and supply agreement with Prasco, LLC, Prasco is commencing shipments of an authorized generic of prescription ZEGERID® (omeprazole/ sodium bicarbonate) Capsules in 20 mg and 40 mg dosage strengths in the U.S. under the Prasco label. ZEGERID is an immediate-release proton pump inhibitor (PPI) approved as a prescription product in the U.S. for the treatment of certain upper gastrointestinal diseases and disorders.

1 Jul 2010

Antibacterial ingredient in honey identified

Sweet news for those looking for new antibiotics: A new research published in the July 2010 print edition of the FASEB Journal explains for the first time how honey kills bacteria. Specifically, the research shows that bees make a protein that they add to the honey, called defensin-1, which could one day be used to treat burns and skin infections and to develop new drugs that could combat antibiotic-resistant infections.

30 Jun 2010

Call for incorporation of scientific evidence into illicit drug policies

Three leading scientific and health policy organizations today launched a global drive for signatories to the Vienna Declaration, a statement seeking to improve community health and safety by calling for the incorporation of scientific evidence into illicit drug policies. Among those supporting the declaration and urging others to sign is 2008 Nobel Laureate and International AIDS Society (IAS) Governing Council member Prof. Fran-oise Barr--Sinoussi, co-discoverer of HIV.

30 Jun 2010

Infection and severe sepsis mortality rates higher in black patients

A greater frequency of severe sepsis among black patients is attributable to higher rates of infection and higher risks of organ dysfunction than what white patients experience, according to a study in the June 23/30 issue of JAMA.

30 Jun 2010

Repeated viral screening for ART patients unnecessary with each donation

European legislation that requires all couples undergoing assisted reproduction treatment (ART) to be screened for HIV and hepatitis at the time of every sperm or egg donation is unnecessary, expensive, and potentially distressing for patients, the 26th annual meeting of the European Society of Human Reproduction and Embryology heard today (Monday).

30 Jun 2010

Cubist Phase 2 trial for efficacy of CXA-101 in complicated urinary tract infections meets objectives

Cubist Pharmaceuticals, Inc., a leading acute care therapeutics company, today announced that the recently-completed Phase 2 study of CXA-101, a novel cephalosporin, compared to ceftazidime for the treatment of complicated urinary tract infections (cUTI) in adults met its study objectives.

30 Jun 2010

Cal/OSHA explores ways to strengthen adult film worker safety regulations

California's of Department Occupational Safety and Health (Cal/OSHA) convened its first meeting of an Advisory Panel to explore strengthening adult film worker safety regulations in California today in downtown Los Angeles. In March, the Cal/OSHA Standards Board voted unanimously to convene the Advisory Panel in order to take public comment from health advocates, industry officials and the general public on whether—and how—to amend state health statutes to better protect adult film workers.

30 Jun 2010

Recent, upcoming FDA efforts address rare, 'neglected' diseases

The FDA's new rare disease review group will hold its first public hearing on Tuesday and Wednesday to discuss how to expand efforts to develop treatments for rare diseases that affect fewer than 200,000 people, Reuters

30 Jun 2010

Original viral genetic sequences still present months after initial infection, says study

Scientists have been surprised to learn that, despite thousands of changes that viruses like HIV undergo in rapid fashion to evade the body's immune system, the original version that caused the infection is still present in the body months later.

30 Jun 2010

White House to release domestic strategy against AIDS

The White House is poised to release the country's first comprehensive domestic strategy against AIDS, as funds to prevent infections have failed to halt the epidemic in those most at risk of the disease, AIDS groups said. Release of the National AIDS Strategy may come as early as today, fulfilling Obama's campaign pledge to unify priorities among federal agencies and state partners, said Mitchell Warren.

30 Jun 2010

UCLA School of Dentistry awarded NIH grant to study methamphetamine's oral, dental health consequences

The abuse of methamphetamine - a powerful and highly addictive psychostimulant that is toxic to the nervous system - has reached epidemic proportions in many parts of the United States. The National Institute on Drug Abuse estimates that more than 10 million Americans have tried methamphetamine, while more than 1.4 million are habitual users.

30 Jun 2010

Greenwire/New York Times examine dengue vaccine development

Greenwire/New York Times reports on the growing number of cases of dengue worldwide, including the CDC's report last month that the virus has now been locally acquired in the continental U.S. for the first time in 65 years. "While a few cases were reported earlier, they were primarily in Americans who had caught the virus abroad or at the Texas-Mexico border," the news service writes.

30 Jun 2010

Routine testing of inmates can reduce HIV incidence in the U.S.

Routine, jail-based HIV testing of inmates can successfully identify a substantial proportion of people unknowingly infected with HIV and could play a critical role in preventing the spread of the disease, according to a new report in this week's U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

29 Jun 2010

Mammalian embryo use different strategies to suppress retroviral infection: Study

Some viruses insert themselves into the host's DNA during infection in a process called retroviral integration, causing several diseases, including AIDS and cancer, notes a Texas A&M researcher who specializes in fetal diseases.

29 Jun 2010

Pluristem advances toward PLX-PAD Phase IIb clinical trials for CLI and Moderate-severe Claudication

Pluristem Therapeutics Inc. today announced that following its meeting with the Paul Ehrlich Institute (PEI), the German regulatory authority for advanced therapy products (ATP), the company is advancing toward designing two Phase IIb clinical trials for its placenta-derived cell therapy product, PLX-PAD, for the treatment of Critical Limb Ischemia (CLI) and Moderate-severe Claudication.

29 Jun 2010

LEAPS vaccine technology generates dendritic cells to stimulate immune system to fight viral illnesses

CEL-SCI Corporation and researchers at the Northeastern Ohio Universities Colleges of Medicine and Pharmacy (NEOUCOM) jointly announced today that a LEAPS-based vaccine (Ligand Epitope Antigen Presentation System) study has demonstrated the technology's potential using dendritic cells to stimulate the immune system to fight viral illnesses and other diseases.

29 Jun 2010

Rare human antibodies protect mice from lethal strains of influenza

Scientists have identified a new, highly conserved molecular target on the influenza A virus and demonstrated that human antibodies against this target are protective in animal models of seasonal and highly-pathogenic avian influenza. The work was conducted by researchers at Theraclone Sciences, with collaborators at University of Wisconsin-Madison, University of Tokyo and Johns Hopkins University; and is reported this week in the online Early Edition of the Proceedings of the National Academy of Sciences.

29 Jun 2010

Disease/Infection News

World Bank, WHO, UNAIDS report offers comprehensive look at HIV/AIDS in Middle East, N. Africa

Gen-Probe's APTIMA Trichomonas assay receives European CE mark

Cubist commences enrollment in Phase 2 study of CXA-201 for complicated intra-abdominal infections

Prasco commences shipments of generic prescription ZEGERID Capsules

Antibacterial ingredient in honey identified

Call for incorporation of scientific evidence into illicit drug policies

Infection and severe sepsis mortality rates higher in black patients

Repeated viral screening for ART patients unnecessary with each donation

Cubist Phase 2 trial for efficacy of CXA-101 in complicated urinary tract infections meets objectives

Cal/OSHA explores ways to strengthen adult film worker safety regulations

Recent, upcoming FDA efforts address rare, 'neglected' diseases

Original viral genetic sequences still present months after initial infection, says study

White House to release domestic strategy against AIDS

UCLA School of Dentistry awarded NIH grant to study methamphetamine's oral, dental health consequences

Greenwire/New York Times examine dengue vaccine development

Routine testing of inmates can reduce HIV incidence in the U.S.

Mammalian embryo use different strategies to suppress retroviral infection: Study

Pluristem advances toward PLX-PAD Phase IIb clinical trials for CLI and Moderate-severe Claudication

LEAPS vaccine technology generates dendritic cells to stimulate immune system to fight viral illnesses

Rare human antibodies protect mice from lethal strains of influenza

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

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