Disease/Infection News

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XOMA expands anti-inflammatory antibody intellectual property portfolio

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced that the U.S. Patent and Trademark Office has issued two new patents that significantly expand the company's intellectual property portfolio relating to its anti-inflammatory antibody, XOMA 052, that targets interleukin-1 beta (IL-1 beta).

13 Apr 2010

Yearly flu shots recommended for adults in 50-64 age group

The proportion of Americans with diabetes ages 18 to 64 who reported getting flu shots the previous year rose from 40 percent to 50.5 percent between 2000 and 2007, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

13 Apr 2010

Strains of Salmonella beginning to emerge in HIV-infected people in Africa

Scientists at the University of Liverpool have discovered that dangerous strains of Salmonella are beginning to emerge in people infected with HIV in Africa.

13 Apr 2010

Malaria No More: Jason Castro enters malaria fight to raise awareness of the disease

Atlantic recording artist Jason Castro was introduced to Malaria No More while still an American Idol finalist through the Idol Gives Back charity program, and was shocked to learn that thousands of kids die every day from a disease that's completely preventable and treatable. Malaria No More announces today that Castro has entered the malaria fight as the inaugural "Stayin' Alive" Ambassador, joining a talented list of celebrities who have supported Malaria No More, including Ashton Kutcher, Forest Whitaker, and American Idols Melinda Doolittle and Elliot Yamin, among others.

13 Apr 2010

New Supramap web-based application to track and stop disease outbreaks

Pathogens can now be easily tracked in time and space as they evolve, an advance that could revolutionize both public health and inform national security in the fight against infectious diseases. Developed by researchers that include scientists at the American Museum of Natural History, Supramap is a new, powerful, web-based application that maps genetic mutations like those among the different strains of avian influenza onto the globe.

13 Apr 2010

Cancer drug, antiviral agent can eradicate active virus infection and tumor: UNC School of Medicine

Important advances in the fight against cancer have come as researchers proved that viruses and cancers interact in ways that were previously unknown to scientists.

13 Apr 2010

Boston Globe examines how PEPFAR budget pressures are affecting AIDS clinics in Africa

"U.S. officials have asked some AIDS clinics overseas to stop enrolling new patients in a U.S.-sponsored program that provides lifesaving antiretroviral drugs, in a bid to stem the rising costs of one of the most ambitious US assistance programs, according to interviews with doctors and official correspondence," the Boston Globe reports.

13 Apr 2010

Research finding suggests HCV interference with hepcidin synthesis

Iron overload, a common feature of chronic liver disorders, has been linked with oxidative DNA damage, insulin resistance and liver steatosis, and with triggering of hepatic stellate cells thus inducing liver fibrosis.

13 Apr 2010

Drug boosting production of immune system protein worsens TB

An experimental drug that boosts production of the immune system protein interferon worsens tuberculosis (TB) in mice, according to scientists from the National Institutes of Health. The drug acts indirectly by drawing certain immune cells, in which Mycobacterium tuberculosis (M.tb) bacteria thrive, to the lungs. The findings may have potential implications for the care of people infected with TB, the authors note. The research is reported in the May 3 issue of Journal of Clinical Investigation, now available online.

13 Apr 2010

Experts begin probe of WHO's response to H1N1

Health experts on Monday began a probe of how the WHO responded to the H1N1 (swine flu) pandemic "nearly a year after global alarm was raised over the new swine flu strain," Agence France-Presse reports (Capella, 4/12).

13 Apr 2010

U.S. seeks to constrain global AIDS program costs

The Boston Globe: "US officials have asked some AIDS clinics overseas to stop enrolling new patients in a US-sponsored program that provides lifesaving antiretroviral drugs" in an effort to stem the rising costs of this assistance program. This step has triggered concern among some AIDS advocates "that the Obama administration is curtailing its commitment to a program that provides lifesaving drugs for 2.4 million people and that many view as President Bush's most successful foreign policy legacy.

13 Apr 2010

San Diego Union-Tribune examines pharma's growing interest in neglected diseases

The San Diego Union-Tribune examines the pharmaceutical industry's growing interest in developing new treatments for what are known as "neglected diseases."

13 Apr 2010

Common drug used to treat Burkitt lymphoma can activate EBV: Study

Important advances in the fight against cancer have come as researchers proved that viruses and cancers interact in ways that were previously unknown to scientists.

13 Apr 2010

AP examines micro-insurance in Africa

The Associated Press examines the growth of micro-insurance in Africa, "a product accessible to those earning less than $2 a day, who pay tiny weekly premiums of sometimes less than a cent."

13 Apr 2010

IDF awarded NIH grant for advancing knowledge in PIDD through continuance of USIDNET program

The Immune Deficiency Foundation (IDF) is pleased to announce that it has been awarded the grant "Resources to Assist Investigations in Primary Immunodeficiency Diseases" from the National Institutes of Health (NIH). This grant will allow IDF to continue to advance the detection, understanding, diagnosis and treatment of primary immunodeficiency diseases (PIDD) through their program, the United States Immunodeficiency Network (USIDNET).

13 Apr 2010

Stem cell scientists receive stimulus grants to study lung and blood disorders

Stem cell scientists at The University of Texas Health Science Center at Houston (UTHealth) were awarded stimulus grants totaling almost $2 million to research experimental treatments for blood disorders and inherited lung diseases affecting children.

13 Apr 2010

Checklist to stay healthy and active during summer season

There are millions of vacation destinations to visit this summer and thousands of sights to see, but there is one surefire way to ruin your trip -- getting sick. Although you may not be thinking about viruses and bacterial infections when you plan your trip, there are a few nasty bugs you should be aware of as you pack your bags.

13 Apr 2010

Gilead Sciences doses first patient in Quad Phase III clinical program

Gilead Sciences, Inc. today announced that it has dosed the first patient in the Phase III clinical program evaluating its investigational fixed-dose, single-tablet "Quad" regimen of elvitegravir, cobicistat (formerly GS 9350), emtricitabine and tenofovir disoproxil fumarate.

13 Apr 2010

Rib-X Pharmaceuticals to present delafloxacin Phase 2 study data at 20th ECCMID

Rib-X Pharmaceuticals, Inc., a development-stage antibiotics company with a broad product pipeline based on its innovative discovery platform, today announced that an oral presentation of data for delafloxacin, its lead antibiotic candidate, will be given at the 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10-14, in Vienna, Austria by Paul G. Ambrose, Pharm.D, FIDSA, Director, Institute for Clinical Pharmacodynamics, Ordway Research Institute.

12 Apr 2010

Automated UV radiation helps decontaminate healthcare-associated pathogens

Attendees of the Fifth Decennial International Conference on Healthcare-Associated Infection were offered a record 37 presentations on the critical role of contaminated environmental surfaces in the transmission of pathogens in healthcare settings.

12 Apr 2010