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CMAJ study summarizes risk factors for severe outcome among patients admitted to hospital with H1N1

A new study in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/cgi/doi/10.1503/cmaj.091823 of all patients in Canada admitted to hospital for H1N1 in the first five months of the outbreak summarizes the risk factors for a severe outcome (www.cmaj.ca). The H1N1 pandemic presents important learnings for clinicians and researchers and data on severe outcomes can help inform future treatment and prevention guidelines.

19 Feb 2010

Data from Novavax's Pivotal 2009 A/H1N1 VLP pandemic influenza vaccine study presented at WHO meeting

Novavax, Inc. today presented to the world's leading pandemic influenza vaccine experts a summary of the recent preliminary safety and immunogenicity data from its Pivotal 2009 A/H1N1 VLP pandemic influenza vaccine study in Mexico.

19 Feb 2010

BioTrends' Stelara second wave report finds increase in prescribing among dermatologists

BioTrends published the second wave of LaunchTrends®: Stelara, highlighting dermatology market trends at three months post launch. The report is based on 76 survey responses and 20 qualitative phone interviews with U.S. dermatologists.

19 Feb 2010

Delay in Vibativ's approval for nosocomial pneumonia to reduce previously forecasted commercial impact

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that delays in the U.S. approval and launch of Theravance/Astellas's Vibativ (telavancin) for the treatment of nosocomial pneumonia will reduce by more than half the commercial impact that it was previously forecasted to garner in the methicillin-resistant Staphylococcus aureus (MRSA) drug market.

19 Feb 2010

New Jersey Superior Court links Roche's Accutane to IBD

In another major courtroom verdict linking powerful acne medication Accutane with long-term inflammatory bowel disease (IBD), a nine-person New Jersey jury has found that pharmaceutical maker Hoffman-La Roche Inc. failed to provide an adequate warning of the possible condition to Andrew McCarrell's prescribing physician, which then led to his development of chronic IBD. Mr. McCarrell, who was 23 at the time he took Accutane, developed a severe case of IBD and thereafter had his colon removed. The jury awarded compensatory damages of $25.16 million to Andy, now in his thirties.

19 Feb 2010

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Malaria remains one of the most deadly infectious diseases. Yet, how Plasmodium, the malaria parasite, regulates its infectious cycle has remained an enigma despite decades of rigorous research.

19 Feb 2010

SRI International establishes new Neurodegenerative Diseases Research Program

SRI International, an independent nonprofit research and development institute, announced today that a new Neurodegenerative Diseases Research Program has been established within its Center for Health Sciences. This new SRI group of neuroscientists and researchers working at the cutting edge of science brings $6.2 million of funding from the National Institutes of Health (NIH), including the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Environmental Health Sciences (NIEHS), and National Institute of General Medical Sciences (NIGMS).

19 Feb 2010

Mayo Clinic's first DCD lung transplantation performed in 59-year-old Illinois man

Lung transplantation is a well-known therapy for patients with end-stage lung disease, but, as with other patients waiting for organs for transplantation, there are more recipients waiting than donors available. A potential solution for patients with end-stage lung disease is donation after cardiac death (DCD). Mayo Clinic reports its - and Minnesota's - first lung transplantation from DCD in the February issue of Mayo Clinic Proceedings.

19 Feb 2010

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

VIRxSYS Corporation, a privately held company developing vaccines and RNA therapies for serious human diseases such as HIV and cardiovascular diseases, announced results from its prophylactic HIV vaccine (VRX1023) study in Rhesus Macaque monkeys during a presentation today at the 2010 Annual Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco, CA.

19 Feb 2010

Sacred Heart Medical Center fined $8,000 for failing to adhere to state and national H1N1 influenza safety standards

On January 29, 2010, Sacred Heart Medical Center was cited and fined $8,000 for failing to adhere to state and national H1N1 influenza safety standards. The Department of Labor and Industries Division of Occupational Safety and Health issued the citation and fine for violation of Center for Disease Control and Occupational Safety and Health Administration guidelines on H1N1 and also for violation of the DOSH Directive on Enforcement Procedures for High or Very High Occupational Exposure Risk to the 2009 H1N1 Influenza.

19 Feb 2010

Group B streptococcus may have significant public health implications: Study

A common bacteria found in many healthy adult females that can cause life-threatening infections when passed to newborns could be introduced to some women through frequent contact with cows, according to a research team led by a Michigan State University pediatrician.

19 Feb 2010

UBC researcher finds improved uptake of highly active antiretroviral therapy

A comprehensive population-based study, conducted by the BC Centre for Excellence in HIV/AIDS (BC-CfE) and presented at the 17th Conference on Retroviruses and Opportunistic Infections in San Francisco, shows that expanded highly active antiretroviral therapy (HAART) coverage was associated with a 50% decrease in new yearly HIV infections among injection drug users.

19 Feb 2010

Untreated gum disease has potentially dangerous implications

The American Academy of Periodontology (AAP) estimates that approximately three out of four Americans suffer from some form of gum disease -- from mild cases of gingivitis, to the more severe form known as periodontitis. However, despite this prevalence, approximately only three percent seek treatment for their gum disease. With increasingly more research indicating that gum disease may be linked to several other diseases, including diabetes, heart disease and certain forms of cancer, maintaining healthy teeth and gums has become more important that ever.

19 Feb 2010

GSK decides to remove potentially hazardous zinc from denture adhesive products

GlaxoSmithKline, the maker of popular denture adhesives Poligrip and Super Poligrip, announced today that it will remove zinc from all of its denture adhesive products. The pharmaceutical giant has added the potentially hazardous mineral to its adhesives for decades, despite overwhelming evidence that consuming large quantities of zinc over an extended period of time can cause serious neurological damage.

19 Feb 2010

UCSF, Genentech partner to discover and develop drug candidates for neurodegenerative diseases

The University of California, San Francisco has signed a partnership agreement with Genentech, Inc., a wholly owned member of the Roche Group, to discover and develop drug candidates for neurodegenerative diseases.

19 Feb 2010

Unusual compounds in pitcher plant could prove effective against human fungal infections

The moment insects like flies, ants and beetles fall into a pitcher, the plant's enzymes are activated and begin dissolving their new meal, obtaining nutrients such as carbon and nitrogen which are difficult to extract from certain soils.

19 Feb 2010

Walker's book focuses on deaths, genetic deformities and other health issues resulting from environmental pollution

Since the brain-injuring virus needs mosquitoes and pigs to spread, government officials should ban standing water in cemetery cisterns and urban drainage ditches. They should keep industrial "piggeries" away from cities and their populations.

19 Feb 2010

Poor prescription practices among doctors may increase antibiotic resistance

A new paper in the February 17th edition of the journal Molecular Cell describes how exposure to low levels of antibiotics increases mutations in E. coli and Staphylococcus bacteria hundreds of times more than normal, making the creation of drug-resistant strains more likely.

19 Feb 2010

WHO recommends H1N1 be added to next year's seasonal flu virus

The WHO is recommending the H1N1 (swine flu) virus be added to the regular flu vaccine for the Northern Hemisphere's 2010-2011 regular flu season, the Associated Press reports (2/18).

19 Feb 2010

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus), today announced that it presented the results of a preclinical study on a prototype HIV/AIDS vaccine at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

18 Feb 2010

Disease/Infection News

CMAJ study summarizes risk factors for severe outcome among patients admitted to hospital with H1N1

Data from Novavax's Pivotal 2009 A/H1N1 VLP pandemic influenza vaccine study presented at WHO meeting

BioTrends' Stelara second wave report finds increase in prescribing among dermatologists

Delay in Vibativ's approval for nosocomial pneumonia to reduce previously forecasted commercial impact

New Jersey Superior Court links Roche's Accutane to IBD

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

SRI International establishes new Neurodegenerative Diseases Research Program

Mayo Clinic's first DCD lung transplantation performed in 59-year-old Illinois man

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

Sacred Heart Medical Center fined $8,000 for failing to adhere to state and national H1N1 influenza safety standards

Group B streptococcus may have significant public health implications: Study

UBC researcher finds improved uptake of highly active antiretroviral therapy

Untreated gum disease has potentially dangerous implications

GSK decides to remove potentially hazardous zinc from denture adhesive products

UCSF, Genentech partner to discover and develop drug candidates for neurodegenerative diseases

Unusual compounds in pitcher plant could prove effective against human fungal infections

Walker's book focuses on deaths, genetic deformities and other health issues resulting from environmental pollution

Poor prescription practices among doctors may increase antibiotic resistance

WHO recommends H1N1 be added to next year's seasonal flu virus

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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