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Antimalarial drug resistance endangers malarial control measures

Evidence of resistance to the antimalarial drug artemisinin and its derivatives threatens efforts to control malaria in Southeast Asia, and experts fear artemisinin resistance may spread from the Thailand-Cambodia border to affect other malaria endemic countries. Evidence to such effect was presented today at the 58th annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

20 Nov 2009

Leading driver of antibiotic selection in nosocomial pneumonia in Europe found

Arlington Medical Resources (AMR) and Decision Resources find that the leading driver of antibiotic selection in nosocomial pneumonia in Europe is broad-spectrum activity against gram-positive and gram-negative pathogens.

20 Nov 2009

WSNA highlights serious concerns about safety of nurses and patients during H1N1 pandemic

Washington State Nurses Association (WSNA), representing more than 1,600 registered nurses at Sacred Heart Medical Center, is holding a press conference today to highlight serious concerns about the safety of nurses and patients at Sacred Heart Medical Center during this H1N1 pandemic.

20 Nov 2009

University of Leeds scientists' discovery could lead to new treatment route for BSE and CJD

A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease (CJD) could be a step closer thanks to a discovery by scientists at the University of Leeds.

20 Nov 2009

H1N1: Bridging the knowledge gap

A commentary in the December issue of The Lancet Infectious Diseases brings to light the gaps in knowledge on the transmission of a common pathogen - the influenza virus - and its impact on decisions about how best to protect health care workers. Infectious diseases specialist Leonard Mermel, DO, medical director of infection control for Rhode Island Hospital, looks at the ongoing debate in light of the H1N1 pandemic, what past research tells us about the spread of influenza, and what is missing in the debate. His commentary is currently available in an online first edition.

20 Nov 2009

WPI researchers develop new model system to study fungal infections

A team of researchers at the Worcester Polytechnic Institute (WPI) Life Sciences and Bioengineering Center at Gateway Park has developed a new model system to study fungal infections. The system can be a powerful tool for screening potential drug targets for conditions like thrush, athlete's foot and vaginal yeast infections, which affect millions of people each year but are difficult to treat with existing medications. Using the new model, the researchers also identified a gene that may be a promising target for a new anti-fungal drug.

20 Nov 2009

Researchers to discover new vaccine against infection from Lyme disease

A protein found in the saliva of ticks helps protect mice from developing Lyme disease, Yale researchers have discovered. The findings, published in the November 19 issue of Cell Host & Microbe, may spur development of a new vaccine against infection from Lyme disease, which is spread through tick bites.

20 Nov 2009

Cigarettes are widely contaminated with bacteria, reveals study

Cigarettes are "widely contaminated" with bacteria, including some known to cause disease in people, concludes a new international study conducted by a University of Maryland environmental health researcher and microbial ecologists at the Ecole Centrale de Lyon in France.

19 Nov 2009

Many pregnant Ugandan women avoid HIV screening

'Prevention is the best cure' is a common expression, but what happens if preventative measures are not used? A large proportion of pregnant Ugandan women are going out of their way not to be HIV tested, increasing the risk of mother-to-child transmission.

19 Nov 2009

Goosby says PEPFAR remains among 'highest priorities' of Obama administration, welcomes partnership with South African president Zuma

Eric Goosby, head of PEPFAR, on Wednesday reemphasized the U.S. commitment to fighting HIV/AIDS globally, the Associated Press reports. Despite concerns by international aid groups that the current economic climate might force HIV/AIDS funding to be scaled back, "Goosby said President Barack Obama and Secretary of State Hillary Rodham Clinton have assured him his program remains among 'the highest priorities,'" the news service writes.

19 Nov 2009

High prevalence of asthma among children with H1N1

A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu.

19 Nov 2009

Pfizer,DNDi partner to Identify NTD drugs; Sanofi-Aventis, medicines for malaria launch drug study

Pfizer and the Drugs for Neglected Diseases Initiative (DNDi) on Wednesday announced plans to team up in an effort to identify new drug candidates for the treatment of three tropical diseases, the Associated Press/Business Week reports. The scientists will test the efficacy of Pfizer drug candidates against sleeping sickness, visceral leishmaniasis, and Chagas disease.

19 Nov 2009

Op-Eds: HIV travel ban; improving sanitation; counterfeit drugs

A "blot" on U.S. HIV/AIDS leadership "ended last month when President [Barack] Obama lifted the prohibition" that kept HIV-positive foreigners from visiting the U.S. or seeking residency, according to a Washington Post editorial. "The process for eliminating the travel ban started under President George W. Bush in July 2008, when he signed legislation that repealed the original statute."

19 Nov 2009

Family planning drive launched during conference in Uganda

Agence France-Presse examines a new U.S.-backed "12 million dollar family planning drive launched" Wednesday during a three-day conference on family planning in Kampala, Uganda. The project aims to "improve access to contraceptives for women in six African nations [including Uganda, Ethiopia, Nigeria, Senegal, Tanzania and Kenya] as well as Indonesia and Pakistan," the news service writes (Simon, 11/18).

19 Nov 2009

Also in Global Health News: HIV/AIDS grant giving; Africa's water resources; sex workers in Malawi

HIV/AIDS program grants made by U.S.-based foundations totaled $618 billion in 2008, an 11 percent increase from the previous year, according to a new report by Funders Concerned About AIDS, the Chronicle of Philanthropy reports. The Bill & Melinda Gates Foundation accounted for the majority of the grants, and when it was "excluded, foundation giving [for HIV/AIDS] actually declined 3 percent compared to 2007."

19 Nov 2009

Adamas Pharmaceuticals expands its Phase 2 TCAD therapy study for influenza A

Adamas Pharmaceuticals, Inc., a privately held company, announced today that it has expanded its Phase 2 clinical study of a proprietary investigational triple-combination antiviral drug therapy for influenza to include centers in the United States, Canada and Europe. The study, which was initiated in August 2009 in the Southern Hemisphere, is designed to investigate Adamas' triple combination antiviral drug (TCAD) therapy as a treatment for influenza A, including novel influenza A/H1N1, the cause of the current flu pandemic.

19 Nov 2009

SinoFresh Nasal Spray effective against 'swine flu' in animal study

SinoFresh Healthcare Products, Inc. announced today the successful results of its initial pilot animal study testing the efficacy of the SinoFresh Nasal Spray product when used on animals infected with the H1N1 virus. The study data suggests that treatment with SinoFresh allowed the infected animals to recover more rapidly from H1N1 infection than did untreated animals. In addition, pre-treatment with SinoFresh Nasal Spray decreased the severity and/or incidence of infection.

19 Nov 2009

First comprehensive, international baseline evidence about pandemics published

Public health officials walking a tightrope between massive demand for vaccines and intense public scrutiny of side effects now have a new standard for evaluating the safety of their vaccination programs.

19 Nov 2009

Exaggerated responses of immune system explain elders’ susceptibility to viral infections

Researchers at Yale School of Medicine have found that exaggerated responses of the immune system explain why the elderly succumb to viral infections more readily than younger people. Published in the November 19 Cell Host & Microbe, the study bucks the general belief that declining immune responses are to blame for susceptibility to viral infections.

19 Nov 2009

Early diagnosis and treatment is crucial for pulmonary hypertension, a rare but deadly disease

We often hear about the perils of high blood pressure, but many Canadians are unaware that high blood pressure in the lungs - known as pulmonary hypertension (PH) - can also have fatal consequences. This month, the Pulmonary Hypertension Association of Canada hopes to raise awareness about PH - a rare but serious disease that can strike at any time and has no regard for race, age or gender.

19 Nov 2009