Disease/Infection News

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Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Creating more effective and safe treatments for COVID-19

When approaching a task, members of a team need to work in synergy. Nothing can be accomplished if you're pulling in different directions.

16 Mar 2023

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Researchers documented the various polymeric materials that can be used to synthesize micelles, which can then be used for targeted cancer therapy by tailoring the micelles to respond to stimuli.

16 Mar 2023

Is there an association between COVID-19 and an increased incidence of temporomandibular disorders?

Researchers assessed the association between COVID-19-related stress, depression, anxiety, and temporomandibular disorders from childhood to adulthood.

16 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Forecasting adverse effects and prognosis in TB patients using AI

A recent study applied AI to forecast the prognosis and adverse effects of TB.

16 Mar 2023

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Efficacy of a single dose of MVA-BN smallpox vaccine against Mpox

A recent The Lancet Infectious Disease study focussed on estimating the effectiveness of a single dose of MVA-BN against Mpox in England. This observational study was conducted following the large-scale vaccination program that immunized the GBMSM group with the MVA-BN vaccine.

15 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

A study published in JAMA Network Open explores the protective efficacy of previous exposure to omicron subvariants and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) omicron BA.5 infection.

15 Mar 2023

Johns Hopkins’ ARISE program may increase the odds of home discharge for hospitalized COVID-19 patients

The Acute Hospital Rehabilitation Intensive Service (ARISE) program, developed in 2020 by the Johns Hopkins Department of Physical Medicine and Rehabilitation (PM&R), may increase the chances of patients hospitalized with COVID-19 getting discharged to their home rather than to a rehabilitation facility that provides post-hospitalization care services.

15 Mar 2023

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

UVA Health researchers have identified a potential treatment to prevent severe COVID-19 in patients at great risk.

15 Mar 2023

Children's immunity to COVID-19 provided by common colds

During the pandemic, it became clear that children who contracted COVID-19 became less ill than adults.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023