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New study highlights the under-reporting of COVID-19 deaths in the US

A study conducted by US-based scientists highlights that a considerable percentage of coronavirus disease 2019 (COVID-19)-related deaths remains unreported in different counties across the United States.

19 Jan 2023

New research reveals that childhood omicron infections have been under-reported in Canadian schools

A recent study from the east coast of Canada evaluated the extent of under-reporting among school children from elementary to high schools.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Diagnosis and treatment of people with long COVID

About 1.4 million people in Canada have been affected by long COVID after infection, or suspected infection, with SARS-CoV-2. A new trio of practice articles in CMAJ (Canadian Medical Association Journal) aims to help clinicians diagnose, assess and treat people with long COVID.

18 Jan 2023

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

Early in the coronavirus disease 2019 (COVID-19) pandemic, pregnant women were thought to be at unusually high risk from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the general population or non-pregnant women. However, later studies failed to agree on the extent and nature of the danger posed by the infection.

18 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers performed immunoglobulin (Ig)M and IgG epitope mapping against 487 SARS-CoV-2 peptides.

18 Jan 2023

Investigational vaccine regimen safe but did not provide protection against HIV acquisition

An investigational HIV vaccine regimen tested among men who have sex with men (MSM) and transgender people was safe but did not provide protection against HIV acquisition, an independent data and safety monitoring board (DSMB) has determined.

18 Jan 2023

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field.

18 Jan 2023

What does the future of clinical trials and evidence-based medicine look like?

In a recent perspective published in Nature Medicine, the researcher shared his vision and future perspectives for the domains of clinical research and evidence-based therapeutics.

18 Jan 2023

What factors are associated with successful dietary weight loss interventions?

A new study explored the factors governing the success of long- and short-term weight loss interventions.

18 Jan 2023

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

Researchers evaluated the efficacy of low-dosage fluvoxamine (50 mg two times a day) over 10 days in the management of mild and moderate-SARS-CoV-2 infections in the US.

18 Jan 2023

COVID-19 is changing behaviors related to how people are exposed to household chemicals

COVID-19 is changing household behaviors related to how we are exposed to various household chemicals linked to poor health outcomes.

18 Jan 2023

Threshold control method could aid in future non-pharmaceutical intervention relaxation policy making

Governments around the world used a variety of techniques known as nonpharmaceutical interventions, or NPIs, to control the spread of COVID-19.

18 Jan 2023

Upregulation of Robo4 expression reduces mortality from severe infection

The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression.

18 Jan 2023

What is the impact of maternal hypertension and mental disorders on neonatal outcomes?

Researchers explored the impact of maternal hypertension and mental disorders on harmful neonatal outcomes.

18 Jan 2023

Exploring a novel amplicon-based mpox virus sequencing strategy

Researchers described the development of a sequencing strategy based on amplicons for mpox detection.

18 Jan 2023

The "Great Escape" by SARS-CoV-2 XBB.1

In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant of concern (VOC) Omicron, which emerged in late 2022.

17 Jan 2023

Disease/Infection News

New study highlights the under-reporting of COVID-19 deaths in the US

New research reveals that childhood omicron infections have been under-reported in Canadian schools

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Diagnosis and treatment of people with long COVID

Does COVID-19 cause adverse pregnancy and neonatal outcomes?

Immunological interactions between asthma, obesity, and the microbiota

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Investigational vaccine regimen safe but did not provide protection against HIV acquisition

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

What does the future of clinical trials and evidence-based medicine look like?

What factors are associated with successful dietary weight loss interventions?

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

COVID-19 is changing behaviors related to how people are exposed to household chemicals

Threshold control method could aid in future non-pharmaceutical intervention relaxation policy making

Upregulation of Robo4 expression reduces mortality from severe infection

What is the impact of maternal hypertension and mental disorders on neonatal outcomes?

Exploring a novel amplicon-based mpox virus sequencing strategy

The "Great Escape" by SARS-CoV-2 XBB.1

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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