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Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

The contamination of surfaces in hospital rooms housing monkeypox patients

Researchers investigated the contamination of surfaces in hospital rooms housing monkeypox patients.

6 Jul 2022

Study finds flaviviruses can manipulate host skin microbiota to produce a scent that attracts mosquitoes

Researchers assessed the impact of mosquito-transmitted flaviviruses on host skin microbiota.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

The global biogeography of bat-origin betacoronaviruses

Researchers developed a spatial and quantitative framework to explore the biogeography of and map the evolutionary risk of bat-origin βCoVs such as SARS-CoV, SARS-CoV-2 and MERS-CoV based on the geographic mosaic theory of coevolution.

6 Jul 2022

How does hybrid immunity shape humoral immune response to SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers illustrated that hybrid severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity widens effective humoral signatures of SARS-CoV-2 vaccinations.

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Research highlights importance of designing effective COVID vaccine allocation strategies

In a recent study posted to the medRxiv* pre-print server, researchers at the University of Melbourne used a modified Susceptible, Exposed, Infectious, and Recovered (SEIR) mathematical model to examine the impact of different vaccine mechanisms and disease characteristics on a population comprised of individuals at high and low risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

6 Jul 2022

Implementing a variety of nonpharmaceutical COVID-19 interventions in Brazil

When the first cases of COVID-19 appeared in Brazil in late February 2020, the twenty-seven Brazilian states responded by implementing a variety of nonpharmaceutical interventions: restrictions on public events, schools, and nonessential commerce, and somewhat later, masking ordinances.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

What role does human microbiota play in COVID-19 severity?

In a recent study published in the journal Advanced Science, researchers explored the dynamic changes in the respiratory tract and gut microbiota in coronavirus disease 2019 (COVID-19) patients. They observed and analyzed these changes during different disease progression stages among patients with differential disease severities.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Latest omicron subvariants are better at eluding vaccines and antibody treatments

The latest omicron subvariants - including the BA.4 and BA.5 forms causing new surges in infections in the United States - are even better at eluding vaccines and most antibody treatments than previous variants, finds a study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

5 Jul 2022

Has the COVID pandemic affected breastfeeding intention?

A new study discusses the impact of the pandemic on breastfeeding practices.

5 Jul 2022

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Convalescent plasma, widely given to severely ill patients hospitalized with COVID-19 during the pandemic, does not improve their ability to survive or recover, according to a national clinical trial led by Vanderbilt University Medical Center and published in the journal CHEST.

5 Jul 2022

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain's blood vessels and may lead to short- and long-term neurological symptoms.

5 Jul 2022

COVID-19 was third leading cause of death in the United States between March 2020 and October 2021

COVID-19 was the third leading cause of death in the United States between March 2020 and October 2021, according to an analysis of national death certificate data by researchers at the National Cancer Institute, part of the National Institutes of Health. The study appears July 5 in JAMA Internal Medicine.

5 Jul 2022

Disease/Infection News

Beyond COVID-19: the potential future applications of mRNA vaccines

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

The contamination of surfaces in hospital rooms housing monkeypox patients

Study finds flaviviruses can manipulate host skin microbiota to produce a scent that attracts mosquitoes

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

The global biogeography of bat-origin betacoronaviruses

How does hybrid immunity shape humoral immune response to SARS-CoV-2?

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Research highlights importance of designing effective COVID vaccine allocation strategies

Implementing a variety of nonpharmaceutical COVID-19 interventions in Brazil

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

What role does human microbiota play in COVID-19 severity?

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Latest omicron subvariants are better at eluding vaccines and antibody treatments

Has the COVID pandemic affected breastfeeding intention?

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

COVID-19 was third leading cause of death in the United States between March 2020 and October 2021

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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