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Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers developed an integrated approach combining NGS, molecular barcoding, machine learning, and bioinformatics to enable high-throughput detection of SARS-CoV-2 variants.

23 Jun 2022

Addressing parents' hesitancy to vaccinate their children against COVID

Researchers examine notable risk factors related to vaccine hesitancy among parents.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

In a recent study published in the Cochrane Library, researchers searched multiple databases to identify randomized controlled trials (RCTs) that evaluated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐neutralizing monoclonal antibodies (mAbs).

23 Jun 2022

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

Speaking releases much more SARS-CoV-2 virus than breathing does

In a recent study published in the journal PNAS, researchers at the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) monitored the airborne mass of speech-generated aerosols using an alternative experimental approach that addressed issues arising from nucleated condensation.

22 Jun 2022

Paxlovid is shown to be effective in treating COVID-19

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers described cases of coronavirus disease 2019 (COVID-19)–related hospitalizations and emergency department (ED) visits in five to 15 days following Paxlovid (Nirmatrelvir/ritonavir ) treatment.

22 Jun 2022

Study analyzing the link between people’s movement and coronavirus spread finds three groups of countries

A new study analyzing the link between people's reduced movement and the spread of coronavirus in 2020 shows that in some countries, the virus spread more rapidly when people stayed at home.

22 Jun 2022

Focus on good surveillance and control measures can help Africa to curb monkeypox

African governments must focus on investing in their surveillance systems and strengthening preparedness to curb the rapid spread of infectious diseases like monkeypox, experts have said.

22 Jun 2022

Wearable activity trackers combined with AI may aid in early identification of COVID-19

Wearable activity trackers that monitor changes in skin temperature and heart and breathing rates, combined with artificial intelligence (AI), might be used to pick up COVID-19 infection days before symptoms start, suggests preliminary research published in the open access journal BMJ Open.

22 Jun 2022

Mathematical model helps predict the risk of COVID-19 transmission in a train carriage

Researchers have demonstrated how airborne diseases such as COVID-19 spread along the length of a train carriage and found that there is no 'safest spot' for passengers to minimise the risk of transmission.

22 Jun 2022

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

Scientists have described the clinical outcomes in hospitalized COVID-19 patients who have been treated with JNK inhibitors together with standard of care.

22 Jun 2022

The role of smartphone apps during the COVID-19 pandemic

In a recent study published in Nature Biotechnology, researchers assessed the role of smartphone apps during the coronavirus disease 2019 (COVID-19) pandemic.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Deaths due to fungal infections during the COVID-19 pandemic in the US

A recent study published in Clinical Infectious Diseases assessed deaths due to fungal infections during the coronavirus disease 2019 (COVID-19) pandemic in the United States (US).

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

Disease/Infection News

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Addressing parents' hesitancy to vaccinate their children against COVID

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

SARS-CoV-2 evades natural killer cell cytotoxic responses

Speaking releases much more SARS-CoV-2 virus than breathing does

Paxlovid is shown to be effective in treating COVID-19

Study analyzing the link between people’s movement and coronavirus spread finds three groups of countries

Focus on good surveillance and control measures can help Africa to curb monkeypox

Wearable activity trackers combined with AI may aid in early identification of COVID-19

Mathematical model helps predict the risk of COVID-19 transmission in a train carriage

Scientists evaluate JNK inhibitors in treating moderate to severe COVID-19 patients

The role of smartphone apps during the COVID-19 pandemic

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Deaths due to fungal infections during the COVID-19 pandemic in the US

Researchers map cancer driver mutations across the human genome

COVID-19 outcomes improved for SARDs patients through Omicron wave

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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