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A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

A team of scientists from the United States has recently defined the substrate envelop of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently available on the bioRxiv* preprint server while awaiting peer review.

31 Jan 2022

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

A new study by Norwegian researchers suggests that vaccine-induced immunological memory and the activation of recall responses in the body yields similar coverage for Omicron and Delta variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

31 Jan 2022

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Minks may be a suitable animal model for testing severe COVID-19 infections, finds a recent bioRxiv* preprint study. While mice and ferrets are used in preclinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is currently no model specific to severe disease.

30 Jan 2022

Study explores factors associated with COVID-19 vaccine hesitancy in individuals with psoriasis

About 40% of people living with psoriasis have had delays to psoriasis treatment and care from the COVID-19 pandemic, according to a new study posted to the medRxiv* server. People of younger age and belonging to an ethnic minority group were more likely to be affected by these disruptions to care.

30 Jan 2022

Children and adolescents respond as well or better than adults to mRNA-1273 COVID vaccination

A recent study assesses the neutralization efficacy of the mRNA-1273 vaccine against the SARS-CoV-2 Omicron variant in children, adolescents, and adults.

30 Jan 2022

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Researchers screen kidney transplant recipients to evaluate their serological responses following immunization with three doses of the COVID-19 vaccine.

30 Jan 2022

Immunity based upon “mild" Omicron infection is weak for Omicron reinfection

Researchers evaluate antibody responses in vaccinated individuals who subsequently developed Delta and Omicron SARS-CoV-2 breakthrough infections.

30 Jan 2022

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Researchers study the interaction between immunity to endemic coronaviruses and SARS-CoV-2.

30 Jan 2022

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Researchers investigate whether the SARS-CoV-2 Omicron variant is more likely to infect vaccinated individuals than the SARS-CoV-2 Delta variant.

30 Jan 2022

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Researchers identify ACE2 as the functional receptor of the two close relatives of MERS-CoV, NeoCoV and PDF-2180-CoV, in bats.

30 Jan 2022

Research evaluates whether HCWs exposed to SARS-CoV-2 at home should work

Researchers assess the risk of healthcare-associated SARS-CoV-2 transmission in a tertiary care mother and child center in Canada.

30 Jan 2022

Using lateral flow testing to define COVID-19 self-isolation period

A recent study discusses the role of lateral flow device testing in potentially improving COVID-19 isolation policies.

30 Jan 2022

Imaging microscopy shows killer T-cells targeting SARS-CoV-2 spike protein

Researchers demonstrate how cytotoxic T-lymphocytes (CTLs) with specificity for SARS-CoV-2 eliminate multiple infected targets.

30 Jan 2022

Adults and children have similar neutralizing antibody responses to SARS-CoV-2 infection

Researchers describe the kinetics of SARS-CoV-2-specific serum antibodies in convalescent children over six months following infection.

30 Jan 2022

New app and lab kit transform a smartphone into COVID-19 / flu detection system

In a potential game changer for COVID-19 pandemic control efforts, a new cell phone app and lab kit have transformed a smartphone into a COVID-19 / flu detection system.

29 Jan 2022

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Jan 2022

Population Council receives $11 million to develop non-hormonal MPT ring for preventing unintended pregnancy, STIs

The Population Council's Center for Biomedical Research has been awarded an $11 million P50 Clinical Research Center Grant from the Eunice Kennedy Shriver National Institute for Child Health and Development of the National Institute of Health.

29 Jan 2022

Treating COVID with antibiotics could be a much simpler way of making people better

A recent study conducted in an Egyptian hospital showed that treating moderate-to-severe COVID patients with either one of two antibiotics (ceftazidime or cefepime, in combination with a steroid) resulted in similar recovery times compared to patients given standard treatment.

29 Jan 2022

COVID-19 disruptions affect one sibling more than the other in multi-child families

COVID-19 disruptions in homes with two or more children affect one sibling more than the other, according to a new study.

29 Jan 2022

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Patients with COVID-19 in the intensive care unit (ICU) prescribed full-dose blood thinners are significantly more likely to experience heavy bleeding than patients prescribed a smaller yet equally effective dose, according to a recent University at Buffalo-led study.

28 Jan 2022

Disease/Infection News

A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Study explores factors associated with COVID-19 vaccine hesitancy in individuals with psoriasis

Children and adolescents respond as well or better than adults to mRNA-1273 COVID vaccination

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Immunity based upon “mild" Omicron infection is weak for Omicron reinfection

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Research evaluates whether HCWs exposed to SARS-CoV-2 at home should work

Using lateral flow testing to define COVID-19 self-isolation period

Imaging microscopy shows killer T-cells targeting SARS-CoV-2 spike protein

Adults and children have similar neutralizing antibody responses to SARS-CoV-2 infection

New app and lab kit transform a smartphone into COVID-19 / flu detection system

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

Population Council receives $11 million to develop non-hormonal MPT ring for preventing unintended pregnancy, STIs

Treating COVID with antibiotics could be a much simpler way of making people better

COVID-19 disruptions affect one sibling more than the other in multi-child families

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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