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Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

The findings from this study suggest that HPNs may inhibit viral replication and budding.

27 Sep 2021

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

A team from the National Institute for Infectious Diseases “L. Spallanzani” (INMI) has recently reported their study on 94 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections (47.9% symptomatic, 52.1% asymptomatic) that occurred after the first or second vaccine dose against SARS-CoV-2 in the Lazio region (Central Italy).

27 Sep 2021

Firefighters on front lines, no strangers to risk, push back against covid vaccine mandates

Kentucky firefighter Jimmy Adams saw the ravages of the coronavirus pandemic when he served as a medic who helped care for the sick on medical calls amid surging covid cases.

27 Sep 2021

SARS-CoV-2 entry inhibitors show antiviral activity

A new study used a combination of a computer-aided drug design approach and cell-based in vitro assays to identify five potential SARS-CoV-2 inhibitors.

27 Sep 2021

Irish meat processing plant COVID-19 outbreak: a retrospective study

A new study involved a retrospective investigation of the outbreak of COVID-19 in an Irish meat plant.

27 Sep 2021

Design of peptide vaccine for SARS-CoV-2

In a recent study, researchers from the US identified two immunogenic non-structural proteins - PLpro and RdRp - from immunodominant gene regions ORF1ab, ORF3a and ORF9b as potential targets for a vaccine against SARS-CoV-2.

27 Sep 2021

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Despite the advent of numerous vaccines and the discovery of passive monoclonal antibodies for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), there remains an urgent need for definitive therapies for coronavirus disease-2019 (COVID-19) patients.

27 Sep 2021

Study suggests two doses of COVID-19 vaccine may offer some protection for kidney transplant patients

Researchers from Toronto, Canada, performed a cohort study to analyze the impact of COVID-19 vaccination on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and clinical outcomes in kidney transplant patients. This study is available on the preprint server, medRxiv.

27 Sep 2021

SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

New research has found that children and youth may be at low risk of severe acute COVID-19, according to a study conducted during the first half of the pandemic and published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210053.

27 Sep 2021

mRNA COVID vaccines prove effective in the elderly

Coronavirus disease 2019 (COVID-19) proved extremely difficult to control once it entered a country – while there were a few success stories such as New Zealand, most countries ended up resorting to lengthy and economically painful lockdowns, among other restriction measures.

27 Sep 2021

COVID-19 pandemic has triggered greatest declines in life expectancy since World War II

The COVID-19 pandemic triggered life expectancy losses not seen since World War II in Western Europe and exceeded those observed around the dissolution of the Eastern Bloc in central and Eastern European countries.

27 Sep 2021

IAVG reviews various challenges to enhance Covid-19 vaccine access

The Independent Allocation Vaccine Group (IAVG) was established by the WHO in January 2021 and is composed of 12 members who serve in their personal, independent capacities to review and assess Vaccine Allocation Decision (VAD) proposals generated by the COVAX Facility Joint Allocation Taskforce (JAT) on the volumes of vaccines that should be allocated to each participant under COVAX within a given time frame.

27 Sep 2021

WHO urges to address the high price and limited production of antibody combination for COVID-19

The World Health Organization (WHO) welcomes the addition of another therapeutic to the world's arsenal against COVID-19, but urges producing companies and governments to address the high price and limited production of the Regeneron antibody combination and ensure safe and appropriate handling of the medicine.

27 Sep 2021

Study shows prior COVID-19 and vaccination protects elderly against variants

In order to qualify the risk posed to the elderly, researchers from MUSE University in France began to investigate data from nursing homes that had faced outbreaks from variants of concern. Their work can be found on the medRxiv* preprint server while awaiting peer review.

27 Sep 2021

New storybook addresses the fears, worries related to COVID-19 pandemic among children

A new book published today aims to help children stay hopeful and positive during the COVID-19 pandemic. The story is a sequel to 'My Hero is You: how kids can fight COVID-19!', published in April 2020.

27 Sep 2021

Global leaders underline their commitment to ensure equitable access to COVID-19 vaccines

Global leaders attending the Global COVID-19 Summit hosted by the United States have again underlined their commitment to ensuring equitable access to COVID-19 vaccines for all countries through COVAX – noting that equitable access is essential to end the acute stage of the pandemic.

27 Sep 2021

Global leaders align with the ACT-Accelerator to end COVID-19 pandemic

Global leaders attending the US-hosted Global COVID-19 Summit on 22 September re-affirmed their commitment to ending the acute phase of the pandemic, and the goals of the ACT-Accelerator, by agreeing targets to provide equitable access to COVID-19 tests, treatments, and vaccines.

27 Sep 2021

COVID-19 vaccine effectiveness barely affected by Delta variant, research suggests

Has the Delta (B.1.617.2) variant reduced vaccine effectiveness? If you ask Ian Foster of Argonne National Laboratory and colleagues, the answer is not really. New research published in the preprint medRxiv* server suggests vaccines approved in the United States are stable and well-performing.

27 Sep 2021

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

A team of international scientists has formed a consortium to map the epitope landscape of a range of therapeutic monoclonal antibodies on the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, the scientists characterized the neutralization potency of these antibodies and have investigated how emerging viral variants with spike mutations can impact antibody-mediated neutralization. They have recently published the consortium findings in the journal Science.

27 Sep 2021

A review of drugs harmful in COVID-19

In a new study, researchers investigate a number of drugs that are believed to potentially worsen outcomes in patients with COVID-19.

26 Sep 2021

Disease/Infection News

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

Characterization of SARS-CoV-2 infections diagnosed after mRNA BNT162b2 vaccination

Firefighters on front lines, no strangers to risk, push back against covid vaccine mandates

SARS-CoV-2 entry inhibitors show antiviral activity

Irish meat processing plant COVID-19 outbreak: a retrospective study

Design of peptide vaccine for SARS-CoV-2

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Study suggests two doses of COVID-19 vaccine may offer some protection for kidney transplant patients

SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

mRNA COVID vaccines prove effective in the elderly

COVID-19 pandemic has triggered greatest declines in life expectancy since World War II

IAVG reviews various challenges to enhance Covid-19 vaccine access

WHO urges to address the high price and limited production of antibody combination for COVID-19

Study shows prior COVID-19 and vaccination protects elderly against variants

New storybook addresses the fears, worries related to COVID-19 pandemic among children

Global leaders underline their commitment to ensure equitable access to COVID-19 vaccines

Global leaders align with the ACT-Accelerator to end COVID-19 pandemic

COVID-19 vaccine effectiveness barely affected by Delta variant, research suggests

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

A review of drugs harmful in COVID-19

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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