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Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

In a recent study published in the journal Pathogens, researchers carried out a molecular docking study for 17 structural analogs prepared from natural maslinic and oleanolic acids and screened them against SARS-CoV-2 main protease. They also experimentally validated the data by determining the half-maximal cytotoxic and inhibitory concentrations of each of the 17 compounds. The researchers investigated whether the compound with antiviral activity affected viral adsorption, replication, or viricidal effect using a plaque infectivity reduction assay.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

An opinion paper by researchers from the US and Italy recently discussed various aspects of monitoring anti-SARS-CoV-2 antibodies before and after receiving COVID-19 vaccination to highlight the pros and cons of this monitoring strategy. This paper is published in the open-access journal Diagnostics.

9 Jun 2021

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

While not a new problem, the spread of misinformation throughout the coronavirus disease 2019 (COVID-19) pandemic has exploded on almost every social media platform. Recently, a group of researchers analyzed conversations on public Facebook groups to explored automated misinformation on mask-wearing. The team published their findings as a research letter in the JAMA Internal Medicine journal.

9 Jun 2021

A closer look at how COVID-19 damages human lungs

A recent study conducted at the United States Department of Energy’s (DOE) Brookhaven National Laboratory provides the first atomic-level detailed model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope protein when bound to human proteins within the lungs. The study was recently published in Nature Communications.

9 Jun 2021

Radiometer launches the next generation of transcutaneous monitoring in Canada

Radiometer has unveiled its Health Canada licensed TCM5 transcutaneous monitor, addressing the critical care needs of neonatal, pediatric, and adult patients, as well as sleep clinic

From Radiometer Medical 9 Jun 2021

Study examines brain scans of COVID-19 patients

In a Journal of Neuroimaging analysis of data obtained from 193 patients with COVID-19 who had brain and/or spine imaging and a lumbar puncture because of neurologic symptoms, investigators found that imaging results were related to the presence of SARS-CoV-2 in the cerebrospinal fluid.

9 Jun 2021

Mix and match COVID-19 vaccines safe and effective: German study

A new preprint study posted to the medRxiv* server shows an AstraZeneca’s ChAdOx1-nCov-19 and Pfizer/BioNTech BNT162b2 COVID-19 vaccine combination is immunologically superior to two AstraZeneca ChAdOx1-nCov-19 doses.

9 Jun 2021

Study explores the immune response to COVID-19-specific vaccines in Brazilian healthcare workers

An Australian-led study will investigate whether it's possible to predict who remains susceptible to SARS-CoV-2 variants after having COVID-19 or receiving a COVID-19-specific vaccine.

9 Jun 2021

New technology allows rapid analysis and mapping of new potential virus variants

Variants of viruses, such as that causing COVID-19, can now be quickly studied in the laboratory, even before they emerge in nature and become a major public health challenge.

9 Jun 2021

Senolytics reduce inflammation, illness, and mortality from COVID in older mice

Mayo Clinic researchers and colleagues at the University of Minnesota showed that COVID-19 exacerbates the damaging impact of senescent cells in the body.

9 Jun 2021

Surgical masks effectively reduce outgoing airborne particles, despite leakage at edges

A new study from the University of California, Davis and the Icahn School of Medicine at Mount Sinai confirms that surgical masks effectively reduce outgoing airborne particles from talking or coughing, even after allowing for leakage around the edges of the mask. The results are published June 8 in Scientific Reports.

9 Jun 2021

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Cyperus rotundus is a plant with a history as herbal medicine, containing many chemical substances frequently found to be drug-like in character: flavonoids, terpenoids, and the like. Compounds sourced from the plant have demonstrated some inhibitory activity against HIV by modulation of the CYP3A4 enzyme, and thus in a drug lead discovery effort, Kumar et al. (July 2021) computationally screened these natural compounds against MPRO in a paper recently published to Computers in Biology and Medicine.

9 Jun 2021

Potent antibody responses to BNT162b2 COVID-19 vaccine among Japanese healthcare workers

In a paper recently uploaded to the preprint server medRxiv* by Nakajima et al. (June 4th, 2021), the antibody responses of over 2,000 Japanese healthcare workers were tracked over a period of several months, with particular regard to serum Immunoglobulin G (IgG) against the SARS-CoV-2 spike protein.

8 Jun 2021

SARS-CoV-2 B.1.1.345 variant carrying E484K mutation detected in New York

The report, published in the journal Clinical Infectious Diseases, revealed that the variant detected has been spreading at an alarming rate since November. By February 2021, it accounted for 12.3 percent of all cases in the area.

8 Jun 2021

Study highlights cigarette smoking and risk perceptions during the COVID-19 pandemic

Last year, people who smoked had a variety of responses to the COVID-19 pandemic, with some increasing their smoking to help them cope and others quitting to potentially lessen their vulnerability to COVID-19.

8 Jun 2021

Unused Johnson & Johnson Covid doses are piling up as FDA waits to see if shelf life can be extended

The Biden administration is encouraging states to hold on to hundreds of thousands of soon-to-expire Covid vaccine doses from Johnson & Johnson, given the possibility that additional data will show the shots are viable beyond their expiration date at month's end.

8 Jun 2021

Research reveals a possible new approach to prevent death among elderly COVID-19 patients

New research from the University of Minnesota Medical School and colleagues at the Mayo Clinic reveals a possible new approach to preventing death and severe disease in elderly people infected with SARS-CoV-2.

8 Jun 2021

TSMC grant could boost TGen's efforts to track SARS-CoV-2 variants

The Translational Genomics Research Institute, an affiliate of City of Hope, today announced a substantial grant from Taiwan Semiconductor Manufacturing Co. Ltd., one of the world's largest manufacturers of computer chips, to help TGen sustain Arizona's fight against COVID-19.

8 Jun 2021

Disease/Infection News

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

A closer look at how COVID-19 damages human lungs

Radiometer launches the next generation of transcutaneous monitoring in Canada

Study examines brain scans of COVID-19 patients

Mix and match COVID-19 vaccines safe and effective: German study

Study explores the immune response to COVID-19-specific vaccines in Brazilian healthcare workers

New technology allows rapid analysis and mapping of new potential virus variants

Senolytics reduce inflammation, illness, and mortality from COVID in older mice

Surgical masks effectively reduce outgoing airborne particles, despite leakage at edges

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Potent antibody responses to BNT162b2 COVID-19 vaccine among Japanese healthcare workers

SARS-CoV-2 B.1.1.345 variant carrying E484K mutation detected in New York

Study highlights cigarette smoking and risk perceptions during the COVID-19 pandemic

Unused Johnson & Johnson Covid doses are piling up as FDA waits to see if shelf life can be extended

Research reveals a possible new approach to prevent death among elderly COVID-19 patients

TSMC grant could boost TGen's efforts to track SARS-CoV-2 variants

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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