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New universal vaccine protects mice against COVID-19 and other coronaviruses

Scientists at the University of North Carolina Gillings School of Global Public Health have developed a universal vaccine that protected mice not just against COVID-19 but also other coronaviruses and triggered the immune system to fight off a dangerous variant.

22 Jun 2021

Combination of biological markers could improve triage and risk prediction in dengue patients

Researchers have identified a combination of biological markers in patients with dengue that could predict whether they go on to develop moderate to severe disease, according to a study published today in eLife.

22 Jun 2021

Do the Moderna and Pfizer COVID-19 vaccines elicit different antibody responses?

A recent study led by scientists from the United States has compared the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response among clinicians who have been immunized with Pfizer/BioNTech or Moderna coronavirus disease 2019 (COVID-19) vaccine.

22 Jun 2021

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

A team of scientists from the Pennsylvania State University, USA, recently analyzed the pharmacodynamics and pharmacokinetics of antiviral drug remdesivir using computational models. Based on the study findings, which are yet to be peer-reviewed, the scientists recommend that for effective inhibition of SARS-CoV-2 infection, remdesivir should be used with other antiviral medicines, or its dosing regimen should be optimized to improve bioavailability.

22 Jun 2021

Is liquid chalk an effective disinfectant of SARS-CoV-2 and influenza viruses?

A recent study, published in the American Society for Microbiology’s journal, mSphere, evaluated the use of many liquid chalk products as antiseptics against the transmission of highly pathogenic human viruses such as influenza A virus (H1N1), SARS-CoV-2, (IAV), and norovirus in a mouse norovirus (MNV) model. The researchers applied chalk before or after virus inoculum and determined the recovery of infectious virus to mimic its use in the gym setting.

22 Jun 2021

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

A review published in Phytotherapy Research discussed the natural anti-SARS-CoV-2 products identified based on in silico prediction. The review’s authors also illustrate the impact of many phytochemicals either alone or in combination with traditional treatments and their potential molecular mechanisms involved in SARS-CoV-2 prevention and treatment.

22 Jun 2021

Is Rand Paul mixing up the vaccine message for Covid survivors?

Last week, Sen. Rand Paul (R-Ky.) posted a Twitter thread asserting that people who have survived a Covid-19 infection were unlikely to be reinfected and have better immunity against variants than those who have been vaccinated against — but not infected by — SARS-CoV-2, the virus that causes Covid.

22 Jun 2021

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

In a recent study, a group of researchers discuss the functional implications of this specific S protein mutation on SARS-CoV-2.

22 Jun 2021

Does SARS-CoV-2 alter the expression of molecules involved in the homeostasis of blood pressure?

A recent study finds that COVID-19 alters the expression of several molecules involved in the homeostasis of blood pressure.

22 Jun 2021

Use of nanotherapeutics in treating coronavirus diseases

Despite advancements in medicine, viral infections still pose a huge threat to human health and are a significant concern for global public health systems.

22 Jun 2021

Coronaviruses identified in two species of Sri Lankan bats

Researchers sampled different species of bats roosting in the Wavul Galge cave in Sri Lanka and found two species harboring alpha- and beta-coronaviruses.

22 Jun 2021

Single-dose of COVID-19 mRNA vaccine reduces symptom duration

A study of workers administered the first dose of the BNT162b2 vaccine showed that they had reduced symptoms and faster viral clearance within six days of administration.

22 Jun 2021

Birthday parties may have boosted infection rates at the height of the COVID-19 pandemic

The link between birthdays and COVID-19 could explain higher infections in counties that did not prevent such gatherings.

22 Jun 2021

New tool exposes deeply entrenched inequities in COVID-19 outcomes

The Urban Health Collaborative, housed in Drexel University's Dornsife School of Public Health, recently published its "COVID-19 Health Inequities in Cities" dashboard - which exposes deeply entrenched inequities in cities across the United States through the lens of comprehensive data on COVID-19 outcomes.

22 Jun 2021

Study: Immune responses may develop against other proteins produced by SARS-CoV-2

All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and nucleocapsid proteins.

22 Jun 2021

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced presentation of the positive Phase 2 safety and efficacy data for oral opaganib (Yeliva®, ABC294640) in hospitalized patients with COVID-19 pneumonia at the World Microbe Forum (WMF) 2021 (poster #: 5574).

21 Jun 2021

Study identifies significant inequalities in the Liverpool 'mass testing' pilot

A study by the University of Liverpool has shown that while asymptomatic COVID-19 testing in Liverpool was popular, significant inequalities were evident between those who got tested and those who didn't.

21 Jun 2021

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

COVID-19 therapies made from antibodies often are given to patients who are at high risk of severe illness and hospitalization. However, there have been nagging questions about whether such antibody therapies retain their effectiveness as worrisome new virus variants arise.

21 Jun 2021

Study shows a robust immune response to COVID-19 vaccine in breastfeeding health workers

A recent study by researchers from Poland, published in the journal Vaccines, shows how levels of IgA and IgG antibodies specific to the spike glycoprotein of SARS-CoV-2 increase in both breast milk and serum samples of mothers following vaccination against COVID-19 – with important implications for further vaccine planning endeavors.

21 Jun 2021

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

A recent review paper by Portuguese and Spanish authors, recently published in the journal Biologics, revealed the current state of knowledge regarding hedgehog health – most notably the presence of infectious agents, diseases and other threats that can affect the health of the population.

21 Jun 2021

Disease/Infection News

New universal vaccine protects mice against COVID-19 and other coronaviruses

Combination of biological markers could improve triage and risk prediction in dengue patients

Do the Moderna and Pfizer COVID-19 vaccines elicit different antibody responses?

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

Is liquid chalk an effective disinfectant of SARS-CoV-2 and influenza viruses?

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

Is Rand Paul mixing up the vaccine message for Covid survivors?

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

Does SARS-CoV-2 alter the expression of molecules involved in the homeostasis of blood pressure?

Use of nanotherapeutics in treating coronavirus diseases

Coronaviruses identified in two species of Sri Lankan bats

Single-dose of COVID-19 mRNA vaccine reduces symptom duration

Birthday parties may have boosted infection rates at the height of the COVID-19 pandemic

New tool exposes deeply entrenched inequities in COVID-19 outcomes

Study: Immune responses may develop against other proteins produced by SARS-CoV-2

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

Study identifies significant inequalities in the Liverpool 'mass testing' pilot

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

Study shows a robust immune response to COVID-19 vaccine in breastfeeding health workers

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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