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Novel mRNA delivery vehicle provides alternative to LNPs for SARS-CoV-2 vaccines

Researchers in the United States have developed an alternative messenger RNA (mRNA) delivery platform to the lipid nanoparticles that are currently used in vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

18 Apr 2021

Overwhelming evidence SARS-CoV-2 is airborne

Researchers in the United States, UK, and Canada have published a commentary challenging the suggestion that the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may not be airborne.

18 Apr 2021

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

Today, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody therapy bamlanivimab, when administered alone, to be used for the treatment of mild-to-moderate COVID-19 in adults and certain pediatric patients.

17 Apr 2021

The shock and reality of catching Covid after being vaccinated

Robin Hauser, a pediatrician in Tampa, Fla., got covid in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of the Pfizer-BioNTech vaccine.

17 Apr 2021

Past COVID-19 infection does not completely protect against reinfection in young people

Although antibodies induced by SARS-CoV-2 infection are largely protective, they do not completely protect against reinfection in young people, as evidenced through a longitudinal, prospective study of more than 3,000 young, healthy members of the US Marines Corps conducted by researchers at the Icahn School of Medicine at Mount Sinai and the Naval Medical Research Center, published April 15 in The Lancet Respiratory Medicine.

17 Apr 2021

Candidate coronavirus vaccines show promising results in early animal testing

A candidate vaccine that could provide protection against the COVID-19 virus and other coronaviruses has shown promising results in early animal testing.

17 Apr 2021

Experimental antiviral drug for COVID-19 shows effectiveness in hamster models

The experimental antiviral drug MK-4482 significantly decreased levels of virus and disease damage in the lungs of hamsters treated for SARS-CoV-2 infection, according to a new study from National Institutes of Health scientists.

17 Apr 2021

Study highlights the importance of mask fit when double masking to protect against COVID-19

A study published today in JAMA Internal Medicine shows that wearing two face coverings can nearly double the effectiveness of filtering out SARS-CoV-2-sized particles, preventing them from reaching the wearer's nose and mouth and causing COVID-19.

17 Apr 2021

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

SARS-CoV-2, the virus that causes COVID-19, likely does not directly infect the brain but can still inflict significant neurological damage, according to a new study from neuropathologists, neurologists, and neuroradiologists at Columbia University Vagelos College of Physicians and Surgeons.

17 Apr 2021

WHO calls for equitable treatment access and health services to everyone affected by Chagas disease

Today on World Chagas Disease Day, the World Health Organization has called for comprehensive and equitable access to health care and services to everyone affected by Chagas disease.

17 Apr 2021

Ask KHN-Politifact: I’ve recovered from Covid. Why do i still have to mask up?

More than 120 million Americans have joined arguably the most sought-after club on Earth: those immunized against the coronavirus.

16 Apr 2021

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.”

16 Apr 2021

Researchers identify risk factors for SARS-CoV-2 reinfection

A team of scientists from the Capital Medical University and Peking University, China, has recently explored the factors responsible for the reactivation of SARS-CoV-2 infection among individuals who have recently recovered from COVID-19. The findings reveal that individuals with lower lymphocyte count or with two or fewer symptoms during the first COVID-19 episode are at higher risk of recurrent infection.

16 Apr 2021

Numerous agents with anti-SARS-CoV-2 potential discovered with crystallographic screening

An international team of researchers focused on the macrodomain part of the non-structural protein 3 (Nsp3) gene product that SARS-CoV-2 uses to overturn the host cell’s natural antiviral response. The team provided a template that can help develop novel antivirals that are direct-acting and can combat the current pandemic.

16 Apr 2021

Study reveals new lineage of tuberculosis-causing bacteria in the eastern part of the continent

Mireia Coscollá, a researcher at the Institute for Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council, has led a study on the bacterium that causes tuberculosis, one of the 10 deadliest diseases in the world, which proves the existence of a new lineage.

16 Apr 2021

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Now, a team of researchers in China and Australia has shown that SARS-CoV-2 infection can affect bone marrow macrophage (BMM)-to-osteoclast differentiation, which may impact the skeletal system.

16 Apr 2021

Elderly patients of female physicians are more likely to be vaccinated against the flu

New UCLA research suggests that elderly patients of female physicians are more likely than those of male physicians in the same outpatient practice to be vaccinated against the flu.

16 Apr 2021

Rapid mRNA vaccination effectively controls SARS-CoV-2 transmission in long-term care facilities

Vaccine rollouts all over the world are aimed at cutting short the coronavirus disease 2019 (COVID-19) pandemic by inducing antibody-mediated immunity to the virus. A new study, recently released on the medRxiv* preprint server, addresses the successful reduction in viral spread and case incidence among residents of long-term care facilities (LTCF).

16 Apr 2021

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

A new study, released on the medRxiv* preprint server, examines the presence of SARS-CoV-2-specific IgA in human milk and its association with the protection of breastfed infants against the disease.

16 Apr 2021

Curcumin nanosystems could be powerful COVID-19 therapeutics

With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19.

16 Apr 2021

Disease/Infection News

Novel mRNA delivery vehicle provides alternative to LNPs for SARS-CoV-2 vaccines

Overwhelming evidence SARS-CoV-2 is airborne

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

The shock and reality of catching Covid after being vaccinated

Past COVID-19 infection does not completely protect against reinfection in young people

Candidate coronavirus vaccines show promising results in early animal testing

Experimental antiviral drug for COVID-19 shows effectiveness in hamster models

Study highlights the importance of mask fit when double masking to protect against COVID-19

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

WHO calls for equitable treatment access and health services to everyone affected by Chagas disease

Ask KHN-Politifact: I’ve recovered from Covid. Why do i still have to mask up?

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

Researchers identify risk factors for SARS-CoV-2 reinfection

Numerous agents with anti-SARS-CoV-2 potential discovered with crystallographic screening

Study reveals new lineage of tuberculosis-causing bacteria in the eastern part of the continent

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Elderly patients of female physicians are more likely to be vaccinated against the flu

Rapid mRNA vaccination effectively controls SARS-CoV-2 transmission in long-term care facilities

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

Curcumin nanosystems could be powerful COVID-19 therapeutics

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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