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Mapping the dominance of the SARS-CoV-2 UK variant in Europe

A research paper recently uploaded to the preprint server medRxiv* by Vespignani et al. (February 22nd, 2021) uses mathematical models to map the spread of this lineage across Europe, establishing that a 50% increase to the transmissibility of the variant would allow it to become dominant in major metropolitan areas by the end of March 2021.

24 Feb 2021

Complement system appears to be specifically implicated in severe COVID-19

Researchers in the United States have conducted a study showing that activation of the complement system is specifically implicated in the pathogenesis of severe coronavirus disease 2019 (COVID-19), rather than being a broader indicator of critical illness.

24 Feb 2021

Travelers to the tropics are more prone to acquiring superbacteria than previously thought

Exploring exposure to superbacteria, researchers at the University of Helsinki and Helsinki University Hospital got unexpected results from an international collaborative study conducted in real time among 20 travelers to Southeast Asia.

24 Feb 2021

Study shows antibody responses persisting 10 months after SARS-CoV-2 infection

Researchers in Italy have conducted a study showing that patients who had tested positive for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still had neutralizing antibodies against the virus 10 months later.

24 Feb 2021

Study takes a closer look at the impact of COVID-19 pandemic on dental hygienists

Despite having been designated as high risk for COVID-19 by the Occupational Safety and Health Administration, a new study finds 3.1 percent of dental hygienists have had COVID-19 based on data collected in October 2020.

24 Feb 2021

Survey finds highest ever vaccination rates during the 2020-2021 flu season

More U.S. adults reported receiving or planning to receive an influenza vaccination during the 2020-2021 flu season than ever before, according to findings from a December 2020 national survey.

24 Feb 2021

A machine-learning approach to track how yellow fever mosquito moves through the environment

The yellow fever mosquito (Aedes aegypti) is a main vector of deadly diseases like dengue fever, chikungunya, and the Zika virus, which result in hundreds of thousands of deaths worldwide each year.

24 Feb 2021

Electronic doctors’ notes could help hospitals plan for surges in COVID-19 cases

A new study, published today in Nature Digital Medicine, found that 'natural language processing' (NLP) of information routinely recorded by doctors - as part of patients' electronic health records - reveal vital trends that could help clinical teams forecast and plan for surges in patients.

24 Feb 2021

Household odorant smell tests could help detect COVID-19, say study

Researchers at the Weizmann Institute of Science and other institutions developed a new tool to help detect COVID-19 infection. The team developed and tested a real-time tool to measure olfactory perception impairment by asking the participants to smell household odorants.

24 Feb 2021

Risk models for West Nile Fever may predict areas of future outbreaks a year in advance

Knowing the environmental and human-related variables that characterize the favorable areas for the incidence of the West Nile virus, a flavivirus that is transmitted from birds to humans by mosquitoes, is essential to identify those places in Europe at high risk of experiencing outbreaks, even before these are registered, thus enabling preventive measures to be taken.

24 Feb 2021

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

The George Washington University announced today its participation in a Sanofi COVID-19 vaccine clinical trial. GW was selected as one of approximately 25 sites in the United States to launch a phase 2 study for its adjuvanted recombinant protein-based COVID-19 vaccine candidate.

24 Feb 2021

COVID-19 hospitalizations still high in England despite recent decline in cases, says study

Results from the latest round of the real-time assessment of community transmission study (REACT-1) study in England indicate that although coronavirus disease 2019 (COVID-19) cases have decreased, the number of hospitalizations remains high.

24 Feb 2021

Basigin does not facilitate SARS-CoV-2 entry, say researchers

Researchers investigated the significance of a transmembrane glycoprotein basigin, or CD147, as a host cell co-receptor required for the entry of SARS-CoV-2. The findings reveal that recombinant human basigin does not interact with full-length spike protein or spike RBD of SARS-CoV-2.

24 Feb 2021

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

New research by a team of scientists at Stanford University School of Medicine in the U.S. found that both the UK and South African SARS-CoV-2 variants display tighter binding to the ACE2 receptor.

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

College students forced to relocate during COVID-19 pandemic are more likely to have depression

Numerous psychiatric studies have documented increased rates of depression and anxiety among those forced to relocate, with sudden moves often affecting individuals' social support and sense of identity and control.

24 Feb 2021

Hyperactive immune system contributes to COVID-19 severity, lung damage

Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease.

24 Feb 2021

International travelers are vulnerable to virulent strains of drug-resistant bacteria

International travelers are particularly vulnerable to virulent strains of drug-resistant bacteria - often picking up several different types during a trip through spending time in the company of other tourists, a new study reveals.

24 Feb 2021

Exhaled breath from infected people can spread COVID-19

COVID-19 can spread from asymptomatic but infected people through small aerosol droplets in their exhaled breath. Most studies of the flow of exhaled air have focused on coughing or sneezing, which can send aerosols flying long distances.

24 Feb 2021

Long-lasting B cells do not recognize emerging SARS-CoV-2 variants, shows study

A new analysis of B cells and more than 1,000 different monoclonal antibodies from 8 patients with COVID-19 shows that, contrary to previous hypotheses, protective B cell responses to the SARS-CoV-2 spike protein remain stable and continue to evolve over a 5-month period, many months after the initial period of active viral replication.

23 Feb 2021

Disease/Infection News

Mapping the dominance of the SARS-CoV-2 UK variant in Europe

Complement system appears to be specifically implicated in severe COVID-19

Travelers to the tropics are more prone to acquiring superbacteria than previously thought

Study shows antibody responses persisting 10 months after SARS-CoV-2 infection

Study takes a closer look at the impact of COVID-19 pandemic on dental hygienists

Survey finds highest ever vaccination rates during the 2020-2021 flu season

A machine-learning approach to track how yellow fever mosquito moves through the environment

Electronic doctors’ notes could help hospitals plan for surges in COVID-19 cases

Household odorant smell tests could help detect COVID-19, say study

Risk models for West Nile Fever may predict areas of future outbreaks a year in advance

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

COVID-19 hospitalizations still high in England despite recent decline in cases, says study

Basigin does not facilitate SARS-CoV-2 entry, say researchers

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

College students forced to relocate during COVID-19 pandemic are more likely to have depression

Hyperactive immune system contributes to COVID-19 severity, lung damage

International travelers are vulnerable to virulent strains of drug-resistant bacteria

Exhaled breath from infected people can spread COVID-19

Long-lasting B cells do not recognize emerging SARS-CoV-2 variants, shows study

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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