Disease/Infection News

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Designed proteins assemble antibodies into modular nanocages

With cues from nature, designing functional molecules enables scientists to nanoengineer and customize for specific uses.

3 Dec 2020

Nanoparticles with neutralizing antibodies can inactivate SARS-CoV-2

Using nanoparticles conjugated with SARS-CoV-2 neutralizing antibodies, researchers demonstrated that intense local heating could inactivate the virus.

3 Dec 2020

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

The COVID-19 pandemic is caused by SARS-CoV-2, a novel beta-coronavirus which has numerous spike proteins on its membrane.

3 Dec 2020

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

The sugar residues decorating the spike (S) protein of SARS-CoV-2 are essential to the viral-receptor binding.

3 Dec 2020

Guidelines for accurate amplicon-based sequencing of SARS-CoV-2

A new study describes much-needed guidelines for reliable viral sequencing, validated in a large group of clinical samples.

3 Dec 2020

School children with no malaria symptoms could be super-spreaders of the disease

School-age children with no malaria symptoms could serve as super-spreaders of the disease, an observation that could open a new chapter on malaria control, a meeting has heard. The new findings from a study that was conducted in Uganda were reported at the virtual annual meeting of the American Society of Tropical Medicine and Hygiene last month (18 November).

3 Dec 2020

COVID-19 mutation mapping identifies escape mutations against therapeutic antibodies

A new study maps all known mutations in the SARS-CoV-2 virus, showing how each contributes to escape from individual antibodies.

3 Dec 2020

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

Researchers from the University of Helsinki have developed a novel bioinformatics pipeline called Lazy pipe for identifying viruses in host-associated or environmental samples.

3 Dec 2020

New initiative seeks to accelerate global collaborative research on COVID-19

During the COVID-19 pandemic, health care professionals and researchers have been confined mostly to using local and national datasets to study the impact of comorbidities, pre-existing medication use, demographics and various interventions on disease course.

3 Dec 2020

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The COVID-19 pandemic has led to millions of deaths across the globe. The causative agent of this disease is the novel coronavirus, SARS-CoV-2.

3 Dec 2020

Pomegranate extract could inhibit the virus that causes COVID-19

Researchers have conducted a study demonstrating the potential antiviral effects of pomegranate extract against SAR-CoV-2.

3 Dec 2020

Novel “multitope” vaccine shows promise in the fight against COVID-19

Researchers have demonstrated the potential of a protein-peptide vaccine to protect against infection with SARS-CoV-2, the agent that causes COVID-19.

3 Dec 2020

Steroids used to treat inflammatory disease increases risk of cardiovascular disease

Researchers have found that prescribed low doses of steroids, often to combat inflammatory diseases, are at an increased risk of cardiovascular diseases.

3 Dec 2020

CUNY SPH launches new initiative to address public concerns about COVID-19 vaccines

The City University of New York Graduate School of Public Health and Health Policy (CUNY SPH) today launched CONVINCE USAsm, part of a global project to increase understanding of factors that influence people's willingness to accept new COVID-19 vaccines, and to promote inclusive public dialogue to reduce vaccine hesitancy.

3 Dec 2020

Study: Infants diagnosed with COVID-19 experienced reversible myocardial injury, heart failure

A 2-month-old infant diagnosed with COVID-19 experienced reversible myocardial injury and heart failure, similar to COVID-19 related heart issues seen in adults, according to a case published in JACC: Case Reports.

3 Dec 2020

Stay-at-home orders are hindering US academic productivity of faculty with young children

The academic productivity of higher education faculty In the United States in the science, technology, engineering, mathematics, and medicine (STEMM) fields with very young children suffered as a result of the stay-at-home orders during the early months of the coronavirus pandemic.

3 Dec 2020

Study uses historical data to predict longer term effects of pandemic on individual economies

Global GDP will drop three percent below pre-pandemic estimates by the end of 2021, with many Western nations seeing "deeper and longer-lasting" effects compared to China and other Asian economies, a study suggests.

3 Dec 2020

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

In a multi-group collaborative involving the National Emerging Infectious Disease Laboratories (NEIDL), the Center for Regenerative Medicine (CReM), and the Center for Network Systems Biology (CNSB), scientists have reported the first map of the molecular responses of human lung cells to infection by SARS-CoV-2.

2 Dec 2020

Study: Individualized treatment plans can benefit both COVID-19 patients, their caregivers

Returning home after a stay in the hospital and a skilled nursing facility is often overwhelming. New research from Regenstrief Institute and Indiana University shows that individualized treatment plans and instructions would be beneficial to both patients and their caregivers.

2 Dec 2020

Chronic kidney disease strongly associated with COVID-related hospitalization

An analysis of Geisinger's electronic health records has revealed chronic kidney disease to be the leading risk factor for hospitalization from COVID-19.

2 Dec 2020

Disease/Infection News

Designed proteins assemble antibodies into modular nanocages

Nanoparticles with neutralizing antibodies can inactivate SARS-CoV-2

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

Guidelines for accurate amplicon-based sequencing of SARS-CoV-2

School children with no malaria symptoms could be super-spreaders of the disease

COVID-19 mutation mapping identifies escape mutations against therapeutic antibodies

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

New initiative seeks to accelerate global collaborative research on COVID-19

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

Pomegranate extract could inhibit the virus that causes COVID-19

Novel “multitope” vaccine shows promise in the fight against COVID-19

Steroids used to treat inflammatory disease increases risk of cardiovascular disease

CUNY SPH launches new initiative to address public concerns about COVID-19 vaccines

Study: Infants diagnosed with COVID-19 experienced reversible myocardial injury, heart failure

Stay-at-home orders are hindering US academic productivity of faculty with young children

Study uses historical data to predict longer term effects of pandemic on individual economies

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

Study: Individualized treatment plans can benefit both COVID-19 patients, their caregivers

Chronic kidney disease strongly associated with COVID-related hospitalization

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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