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Moderna's COVID-19 vaccine nearly 95% effective

US company Moderna have just released their early phase 3 clinical trial results for their COVID-19 vaccine which is nearly 95% effective.

16 Nov 2020

Researchers explain why COVID-19 infects older people and spares younger children

Researchers at Vanderbilt University Medical Center (VUMC) and their colleagues have determined a key factor as to why COVID-19 appears to infect and sicken adults and older people preferentially while seeming to spare younger children.

16 Nov 2020

Royal Government of Cambodia commits to eliminating the deadliest strain of malaria

The Royal Government of Cambodia (RGC) today committed to eliminating Plasmodium falciparum within the next few months, and to maintaining zero cases by 2023, through the launch of an innovative and targeted approach for the ‘last mile’ of malaria elimination in the country.

16 Nov 2020

Long-term care workers, grieving and under siege, brace for COVID’s next round

In the middle of the night, Stefania Silvestri lies in bed remembering her elderly patients' cries.

16 Nov 2020

Homeless shelters grapple with COVID safety as cold creeps in

Ben Barnes has slept in abandoned buildings, hallways and alleys. For the past year or so, he's been staying at the city's largest homeless shelter, Pacific Garden Mission, in the shadows of the famous skyline.

16 Nov 2020

Study sheds new light on the immune system response to COVID-19

A team of immunology experts from research organizations in Belgium and the UK has come together to apply their pioneering research methods to put individuals' COVID-19 responses under the microscope.

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

Study investigates best practices for mechanical ventilation in people with acute respiratory failure

It's a decision being made thousands of times over inside hospitals all around the country: is it time to place a patient struggling to breathe on a ventilator?

16 Nov 2020

Study: High-dose blood thinners have no additional benefit in COVID-19 patients

While COVID-19 infected patients should be treated with standard anticoagulation therapies, such as blood thinning medication, a new study by researchers at the George Washington University (GW) shows that anticoagulating patients at higher doses, without traditional medical indications to do so, may be ineffective and even harmful.

16 Nov 2020

Difference in antibody evolution could predict COVID-19 outcomes

For COVID-19, the difference between surviving and not surviving severe disease may be due to the quality, not the quantity, of the patients' antibody development and response, suggests a new Cell paper published by Galit Alter, PhD, a member of the Ragon Institute of MGH, MIT and Harvard.

16 Nov 2020

Global health leaders discuss the urgent funding needs of ACT Accelerator

Heads of state, global health leaders, scientists, and the private sector have come together at the Paris Peace Forum this week to discuss how to meet the urgent funding needs of the ACT Accelerator.

16 Nov 2020

Study: 68% of people believe they should ‘reach out’ to carers during coronavirus second wave

Amidst a coronavirus second wave, a study has found that 68% of people believe they should ‘reach out’ to carers more often – with 60% of respondents only asking carers how they are ‘now and again’, ‘rarely’ or ‘almost never’; leaving carers at risk of feeling forgotten.

16 Nov 2020

Primate model helps detect features of COVID-19 virus

Features of the SARS-CoV-2 virus causing COVID-19, which could be useful for developing vaccines and treatment strategies, were identified using a nonhuman primate model developed at the Korea Research Institute of Bioscience and Biotechnology (KRIBB).

16 Nov 2020

Study explains why conservatives and liberals differ on COVID-19 threat

Throughout the COVID-19 pandemic, political ideology has been perhaps the strongest predictor of consumers' perceptions of the coronavirus' threat.

16 Nov 2020

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

The turning point for people with COVID-19 typically comes in the second week of symptoms. As most people begin to recover, a few others find it increasingly difficult to breathe and wind up in the hospital.

16 Nov 2020

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers at Georgetown University Medical Center have successfully used molecules comprised of small strands of RNA to shut down the production of destructive proteins generated by the COVID-19 virus.

16 Nov 2020

New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

De'Broski Herbert has a philosophy that's guided his career researching helminths, or parasitic worms, and their interaction with their hosts' immune systems: "Follow the worm."

15 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

The paper, put together by a team of scientists based in the United Kingdom and Italy, also underscored the need for healthcare policies to account for the very real possibility of inadequate protective personal equipment (PPE), staff and hospital capacity, aggravated by the increased number of pediatric infections.

15 Nov 2020

Disease/Infection News

Moderna's COVID-19 vaccine nearly 95% effective

Researchers explain why COVID-19 infects older people and spares younger children

Royal Government of Cambodia commits to eliminating the deadliest strain of malaria

Long-term care workers, grieving and under siege, brace for COVID’s next round

Homeless shelters grapple with COVID safety as cold creeps in

Study sheds new light on the immune system response to COVID-19

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Study investigates best practices for mechanical ventilation in people with acute respiratory failure

Study: High-dose blood thinners have no additional benefit in COVID-19 patients

Difference in antibody evolution could predict COVID-19 outcomes

Global health leaders discuss the urgent funding needs of ACT Accelerator

Study: 68% of people believe they should ‘reach out’ to carers during coronavirus second wave

Primate model helps detect features of COVID-19 virus

Study explains why conservatives and liberals differ on COVID-19 threat

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

New data highlights safety concerns on rAAV vectors used in gene therapy

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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