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Highly sensitive saliva test for SARS-CoV-2 virus antigens can deliver result in under 15 minutes

Mass testing that is fast, non-invasive and able to identify cases before people show symptoms holds the key to boosting COVID-19 detection, improving contact tracing and managing disease outbreaks.

20 Oct 2020

Scientists suggest that anti-malarial drugs could be repurposed to treat COVID-19

An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and that they should be assessed for efficacy in clinical trials.

20 Oct 2020

Siemens Healthineers launches rapid antigen test for the detection of SARS-CoV-2

As society continues to navigate through the COVID-19 pandemic, there is a critical public health need to get ahead of the spread with a fast and simple testing for all.

From Siemens Healthineers 20 Oct 2020

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

When Terry Mutter woke up with a headache and sore muscles on a recent Wednesday, the competitive weightlifter chalked it up to a hard workout.

20 Oct 2020

Older COVID patients battle ‘brain fog,’ weakness and emotional turmoil

For months, as Marilyn Walters has struggled to recover from COVID-19, she has repeated this prayer day and night.

20 Oct 2020

Fever and cough best indicators for COVID-19 in children and adolescents

Most testing is driven by fever, persistent cough of recent onset, and abnormalities in smell. Such symptoms are considered indicative of continuing SARS-CoV-2 infection, requiring quarantine of all such individuals until they test negative for the virus. This approach is justifiable in adults since fever and cough from other causes are rare in healthy adults.

20 Oct 2020

Older males who have recovered from COVID-19 are best plasma donors for treatment

Sex, age, and severity of disease may be useful in identifying COVID-19 survivors who are likely to have high levels of antibodies that can protect against the disease, according to a new study co-led by researchers at Johns Hopkins Bloomberg School of Public Health.

20 Oct 2020

Study helps restore retinal and visual functions of mice models of inherited retinal disease

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

20 Oct 2020

Template for COVID-19 management in a rural health system

As the COVID-19 pandemic continues to challenge existing health networks, a new study published on the preprint server medRxiv in October 2020 reports on a strategy to address existing health care disparities in rural and urban areas of the USA. This should draw attention to the need for more such systems to ensure proper rural healthcare in the current and future pandemics.

20 Oct 2020

Androgen deprivation strategies could help mitigate SARS-CoV-2 infection

Since the beginning of the COVID-19 pandemic, researchers have noted that women are generally less severely affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This has led to the exploration into estrogen and androgens' role in the hyperinflammatory clinical phenotypes of COVID-19. A recent study published on the preprint server bioRxiv shows that drugs targeting androgens and TMPRSS2 inhibitors may potentially combat the pandemic.

20 Oct 2020

Study shows concerning levels of COVID-19 vaccine hesitancy

More than a third of people (34%) in Turkey and one sixth of people (17%) in the UK are 'hesitant' about a COVID-19 vaccine, according to a study by UCL and Dokuz Eylul University in Turkey.

20 Oct 2020

New research finds marked impact of COVID-19 on osteoporosis management

A new study published prior to World Osteoporosis Day finds that the COVID-19 pandemic, which has severely affected management of non-communicable diseases, is markedly impacting the management of osteoporosis as judged by access to online FRAX fracture risk assessments.

20 Oct 2020

New inhaled treatment may lead to self-administered therapy for COVID-19

An inhaled treatment against the SARS-CoV-2 virus may lead to a future self-administered therapy for COVID-19, the pandemic that has killed more than 1 million people worldwide.

20 Oct 2020

The connection between severe COVID-19 and white blood cell counts

However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

19 Oct 2020

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-based disease modeling and computational approach is crucial for simulating the host immune response in fatal COVID-19 patients.

19 Oct 2020

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Recently, researchers reported a study in which they analyzed the structure and dynamics of the spike protein using multiple molecular dynamic simulations. Their study is published on the preprint server bioRxiv.

19 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

Scientists find striking acceleration in medieval plague transmission over 300 years

McMaster University researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

19 Oct 2020

Antigenic imprinting of sarbecovirus

A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

19 Oct 2020

Disease/Infection News

Highly sensitive saliva test for SARS-CoV-2 virus antigens can deliver result in under 15 minutes

Scientists suggest that anti-malarial drugs could be repurposed to treat COVID-19

Siemens Healthineers launches rapid antigen test for the detection of SARS-CoV-2

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

Older COVID patients battle ‘brain fog,’ weakness and emotional turmoil

Fever and cough best indicators for COVID-19 in children and adolescents

Older males who have recovered from COVID-19 are best plasma donors for treatment

Study helps restore retinal and visual functions of mice models of inherited retinal disease

Template for COVID-19 management in a rural health system

Androgen deprivation strategies could help mitigate SARS-CoV-2 infection

Study shows concerning levels of COVID-19 vaccine hesitancy

New research finds marked impact of COVID-19 on osteoporosis management

New inhaled treatment may lead to self-administered therapy for COVID-19

The connection between severe COVID-19 and white blood cell counts

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Scientists find striking acceleration in medieval plague transmission over 300 years

Antigenic imprinting of sarbecovirus

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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