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Dried blood spot samples accurately detect anti-SARS-CoV-2 S glycoprotein antibodies

Using dried blood spot samples (DBS) is an accurate alternative to venous blood in detecting SARS-CoV-2 antibody tests, a new study by immunology experts at the University of Birmingham has found.

6 Oct 2020

Analysis: ‘Don’t be afraid of COVID’? Not buying it, unless businesses do job right

As stores, restaurants, airlines and offices try to lure clients back, this is what they need to do to earn my business: Make me feel safe — no, make me be as safe as possible. As I've begun to explore old haunts, some are doing a fabulous job. Others are not.

6 Oct 2020

Easier-to-use coronavirus saliva tests start to catch on

As the coronavirus pandemic broke out across the country, health care providers and scientists relied on the standard method for detecting respiratory viruses: sticking a long swab deep into the nose to get a sample. The obstacles to implementing such testing on a mass scale quickly became clear.

6 Oct 2020

Campus dorm resident assistants adjust to a new role: COVID cop

Breaking up parties, confiscating booze and answering noise complaints — being a resident adviser has always required a willingness to be the "bad guy" and uphold university policy despite the protests of friends and peers.

6 Oct 2020

Supercharged "clones" trigger the re-emergence of scarlet fever

A University of Queensland-led team of international researchers says supercharged "clones" of the bacteria Streptococcus pyogenes are to blame for the resurgence of the disease, which has caused high death rates for centuries.

6 Oct 2020

Older heavier COVID-19 positives likely to be superspreaders

The spread of SARS-CoV-2 is known to be through respiratory droplets as well as via aerosols, composed of minute particles normally exhaled during natural breathing.

6 Oct 2020

SARS-COV-2 traveled from China to West Africa directly or via Europe

With the onset of COVID-19, the focus of medical research has been on tracing the origin of SARS-CoV-2, which was first reported in China’s Wuhan city.

6 Oct 2020

SARS-CoV-2 prevalence in England “Higher than at any time from May 2020.”

The UK was badly hit by the COVID-19 pandemic, with the numbers of patients requiring hospitalization high during the first wave of the infection.

6 Oct 2020

Plasma ACE2 concentration associated with increased risk of major cardiovascular events

A team of scientists at the Population Health Research Institute, Hamilton Health Sciences, and McMaster University, Hamilton, in Ontario, Canada, revealed that increased plasma ACE2 levels in the blood could indicate a higher risk of major cardiovascular events. The study is published in the journal The Lancet.

6 Oct 2020

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

A new study published on the preprint server bioRxiv* aimed to investigate the impacts of COVID-19 on people with various illnesses. Specifically, the researchers at the Rockefeller Cancer Institute, and the University of Arkansas for Medical Sciences wanted to see the effects of COVID-19 on patients with cancer and other infectious diseases.

6 Oct 2020

COVID-19 increases flu vaccine acceptance in the U.K., study finds

In the United Kingdom, a team of researchers at Imperial College London has found that the coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has increased vaccination acceptance among the study participants. The research is published on the preprint server medRxiv.

6 Oct 2020

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

A postdoctoral researcher at the University of California, Riverside, has discovered human papillomavirus, or HPV, vaccination mandates fall short of ensuring both higher levels of uptake and equal uptake of the vaccine across socioeconomic and racial-ethnic groups.

6 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

Study shows why antiretroviral therapy does not work in certain HIV patients

Increasingly, UPMC's chief of infectious diseases - a well-regarded expert in HIV/AIDS - is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus in check, but testing says otherwise.

6 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Thiopurines could help stop viral replication in human coronaviruses

Researchers from the Department of Microbiology & Immunology, Dalhousie University, University of Calgary, and Department of Biochemistry and Molecular Biology, University of British Columbia, Canada, worked with human coronaviruses in cell cultures to look for drugs that might prevent accumulation and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Oct 2020

Cats and dogs are low risk for SARS-CoV-2 transmission to humans

Researchers from the College of Veterinary Medicine and Biomedical Sciences, Colorado State University studied the possible transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among domestic cats and dogs.

5 Oct 2020

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

Youjia Guo et al. in a recent bioRxiv preprint paper demonstrate the robust performance of mouse anti-SARS-CoV-2 spike monoclonal antibodies in immunoassays, including western blotting, ELISA, immunofluorescence, and immunoprecipitation and also neutralizing activity in vitro against SARS-CoV-2 infection.

5 Oct 2020

Development of a coarse-grained model of SARS-CoV-2 virion

A team of scientists of the University of Chicago and the University of California San Diego has developed a coarse-grained (CG) model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virion. The model can be used as a valuable resource to perform multiscale simulations of the SARS-CoV-2 virion. The study is currently available on the bioRxiv* preprint server.

5 Oct 2020

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

Researchers in the United States and Canada have discovered a monoclonal antibody that potently neutralizes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

5 Oct 2020

Disease/Infection News

Dried blood spot samples accurately detect anti-SARS-CoV-2 S glycoprotein antibodies

Analysis: ‘Don’t be afraid of COVID’? Not buying it, unless businesses do job right

Easier-to-use coronavirus saliva tests start to catch on

Campus dorm resident assistants adjust to a new role: COVID cop

Supercharged "clones" trigger the re-emergence of scarlet fever

Older heavier COVID-19 positives likely to be superspreaders

SARS-COV-2 traveled from China to West Africa directly or via Europe

SARS-CoV-2 prevalence in England “Higher than at any time from May 2020.”

Plasma ACE2 concentration associated with increased risk of major cardiovascular events

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

COVID-19 increases flu vaccine acceptance in the U.K., study finds

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Study shows why antiretroviral therapy does not work in certain HIV patients

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

Thiopurines could help stop viral replication in human coronaviruses

Cats and dogs are low risk for SARS-CoV-2 transmission to humans

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

Development of a coarse-grained model of SARS-CoV-2 virion

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

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