Disease/Infection News

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SARS-CoV-2 containment and elimination strategy will require long-term population-wide prevention measures

By introducing a model that reveals long SARS-CoV-2 transmission chains and inadequate passive surveillance systems, a new medRxiv* preprint paper shows that bringing the infection completely under control will have to rely on presumptive, stringent, longer and more burdensome population-wide prevention measures already employed against community transmission.

7 Sep 2020

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

7 Sep 2020

Three-year Indonesia trial produces encouraging results for dengue control

A three-year trial in Indonesia has produced encouraging results that show a significant reduction in the number of dengue cases.

7 Sep 2020

Important research on SARS-CoV-2 proteins using proximity labeling

A team of Canadian scientists has recently discovered a wide-range interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host proteins using proximity-dependent biotinylation approaches.

7 Sep 2020

COVID-19 caused substantial disruptions to essential health services in most countries

The COVID-19 pandemic caused substantial disruptions in essential health services in 9 out of 10 countries surveyed by WHO.

7 Sep 2020

A potential new way of treating Alzheimer’s Disease

In this interview, Dr. Brad. L. Heckman speaks to News-Medical about a new pathway that could potentially treat Alzheimers disease.

7 Sep 2020

Pooled saliva testing increases COVID-19 testing capacity

Now, a new study by researchers at Yale School of Medicine and published on the preprint server medRxiv in September 2020 shows that pooled saliva samples can save resources and increase testing capacity, making a significant difference in the management of the pandemic.

7 Sep 2020

D-dimer - A sensitive novel biomarker of COVID-19 mortality

Now, a new study published on the preprint server medRxiv* reports the use of D-dimer in predicting the risk of mortality in COVID-19.

7 Sep 2020

Rehabilitation speeds coronavirus recovery

Now, a team of researchers at the University Clinic in Innsbruck in Austria has found that the long-term lung and heart damage in coronavirus disease (COVID-19) patients who recovered tend to improve over time.

7 Sep 2020

Using proteins to track SARS-CoV-2 infections through wastewater

A new study published on the preprint server medRxiv* in September 2020 describes the measurement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins in wastewater as a reliable way to track the virus in the community.

6 Sep 2020

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice and performs much better than a conventional mRNA vaccine. This could allow single-dose immunization, allowing progress towards global vaccination.

6 Sep 2020

Seasonal influenza and COVID-19 risk

In a new study published on the preprint server medRxiv, researchers from Laval University and McGill University in Canada reviewed evidence from 18 relevant studies on a possible interaction between influenza vaccines on non-influenza respiratory disease (NIRD).

6 Sep 2020

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Based on structural similarities with other targets of the gamma-secretase system, researchers from Columbia University Irving Medical Center in the United States show that the SARS-CoV-2 receptor for cell entry may be affected by its proteolytic activity. Their results are currently freely available in a bioRxiv preprint paper.

6 Sep 2020

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

With the use of an accurate high throughput assay, researchers from the Weizmann Institute of Science and Magen David Adom Blood Services in Israel showed substantial inter-individual variability and antibody cross-reactivity against seasonal coronaviruses upon SARS-CoV-2 infection, with important implications for immune surveys and vaccines. The study is currently available on the medRxiv* preprint server.

6 Sep 2020

Transparent Government builds trust and successful COVID-19 containment

The combined impact of the pandemic and these non-pharmaceutical interventions (NPIs) has taken a heavy toll on society, and this has led to much discussion as to the relative merits of these measures. A recent study published on the preprint server medRxiv in September 2020 shows that public trust is vital for the success of any such intervention.

6 Sep 2020

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

In March, in the early days of the coronavirus pandemic in Europe, a tweet from the French Health Minister, Olivier Verán, advised patients with COVID-19 not to take ibuprofen, an anti-inflammatory drug with analgesic and antipyretic properties.

5 Sep 2020

Monitoring the activity of unconventional T cells could predict COVID-19 severity

Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells.

5 Sep 2020

MIS-C linked to COVID-19 damages children's hearts

Multisystem inflammatory syndrome in children (MIS-C), believed to be linked to COVID-19, damages the heart to such an extent that some children will need lifelong monitoring and interventions, said the senior author of a medical literature review published Sept. 4 in EClinicalMedicine, a journal of The Lancet.

5 Sep 2020

COVID-19 is not characterized by a cytokine storm, shows study

Does the COVID-19 cytokine storm exist? Inflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known as "cytokine storm", it can cause harm to the patient.

5 Sep 2020

Early identification, treatment is vital to avoid COVID-19-related health anxieties in children

Early identification and treatment is vital to avoid long-term mental health consequences from COVID-19 among children and young people, say researchers.

5 Sep 2020

Disease/Infection News

SARS-CoV-2 containment and elimination strategy will require long-term population-wide prevention measures

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Three-year Indonesia trial produces encouraging results for dengue control

Important research on SARS-CoV-2 proteins using proximity labeling

COVID-19 caused substantial disruptions to essential health services in most countries

A potential new way of treating Alzheimer’s Disease

Pooled saliva testing increases COVID-19 testing capacity

D-dimer - A sensitive novel biomarker of COVID-19 mortality

Rehabilitation speeds coronavirus recovery

Using proteins to track SARS-CoV-2 infections through wastewater

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

Seasonal influenza and COVID-19 risk

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

Transparent Government builds trust and successful COVID-19 containment

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

Monitoring the activity of unconventional T cells could predict COVID-19 severity

MIS-C linked to COVID-19 damages children's hearts

COVID-19 is not characterized by a cytokine storm, shows study

Early identification, treatment is vital to avoid COVID-19-related health anxieties in children

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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