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Fewer antibiotic prescriptions leads to fewer superbugs

That's the take-home message behind a new study in the Oct. 15 issue of Clinical Infectious Diseases, now available online. The study found that reducing antibiotic use for pediatric respiratory tract infections resulted in lower rates of carriage of drug-resistant bacteria.

6 Sep 2005

Immune cells known as macrophages linked to growth of lymph vessels in eyes,

Scientists at Schepens Eye Research Institute have discovered that a particular immune cell contributes to the growth of new lymph vessels, which aid in healing. This cell, known as a macrophage, is called in by the body during the wound healing process.

6 Sep 2005

When it comes to heart disease women get worse treatment than men

According to a new study, women in Europe who visit their doctor with the symptoms of possible heart disease are not taken as seriously as men.

6 Sep 2005

Single molecular anchor holds the key to treating many types of bacterial meningitis

By blocking the molecule's anchoring ability, researchers may be able to find a way to stave off the most common serious infection of the central nervous system and a major cause of childhood death and disability. The researchers' findings appear in the September 2005 issue of the Journal of Clinical Investigation.

5 Sep 2005

Phase II clinical study of ularitide

The European Society of Cardiology (ESC) today highlighted results of a Phase II clinical study of ularitide, a synthetic form of a natriuretic peptide synthesized in the kidney for patients with acute decompensated congestive heart failure (ADHF).

5 Sep 2005

Benefits of starting CHF treatment with beta-blocker, bisoprolol

Initiating treatment with the selective beta-blocker, bisoprolol, is as effective and well tolerated as beginning treatment with an ACE inhibitor. However, starting treatment with bisoprolol may reduce the risk of death especially in the first year of treatment.

5 Sep 2005

CT scans that detect calcium deposits in heart arteries can help predict the risk of coronary heart disease

Even among relatively young and healthy men, CT scans that detect calcium deposits in heart arteries can help predict the risk of coronary heart disease, according to a new study in the Sept. 6, 2005, issue of the Journal of the American College of Cardiology.

5 Sep 2005

World's largest study on acute coronary syndromes

A Canadian-led study involving researchers from 41 countries has demonstrated in the world's largest study of acute coronary syndromes (ACS) that a new anti-thrombotic therapy is safer and as effective as the traditional therapy used in preventing heart attacks, death and ischemia in people with serious heart conditions.

5 Sep 2005

Significant advance in the study of small ribonucleic acids

Scientists from the University of Delaware have made a significant advance in the study of small ribonucleic acids (RNAs), discovering 10 times more small RNAs in the plant Arabidopsis than previously had been identified. The advance is reported in the Sept. 2 issue of Science magazine.

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

Immunosuppressive drug mycophenolate mofetil may be effective in controlling inflammatory eye diseases

The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by Johns Hopkins' Wilmer Eye Institute.

4 Sep 2005

Abstinence-only education can influence teen sexual behavior and beliefs

The study examined the effectiveness of For Keeps, an abstinence-until-marriage sex education program that has been presented to more than 25,000 students at public and private schools in the Greater Cleveland area.

4 Sep 2005

New key evidence supports claims that some types of cancer originate with defects in stem cells

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells.

4 Sep 2005

Cochlear implants' performance not affected by amount of hearing loss in the implanted ear

Hearing-impaired individuals with severe to profound hearing loss and poor speech understanding who possess some residual hearing in one ear may experience significant communication benefit from a cochlear implant even if it is placed in the worse-hearing ear, a Johns Hopkins study suggests.

1 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

Molecular switch that turns on the production of myelin

Scientists at New York University School of Medicine report in a new study that they have identified the molecular switch that turns on the production of myelin, the fatty insulation around nerve cells that ensures swift and efficient communication in the nervous system.

1 Sep 2005

Potential new way to fight HIV

Researchers have confirmed for the first time the benefit of an innate defense system present in the few patients who remain healthy after years of infection with HIV despite receiving no treatment, according to an article published in the September edition of the Journal of Virology.

1 Sep 2005

Study points to link to neurodegenerative disease target

A University of California - San Francisco (UCSF) study has found that a specific signaling link between neurons and muscles in the fruit fly is essential for keeping the insect's nervous system stable.

1 Sep 2005

Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

St. Jude Children’s Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients.

1 Sep 2005

Attention doctors: Want patients to follow your advice? Treat them with dignity

In a national survey of more than 5,000 Americans, those who said they were treated with dignity during their last medical encounter were more likely to report higher levels of satisfaction with their care, adhere to therapy and get preventive services.

1 Sep 2005

Drug Trial News

Fewer antibiotic prescriptions leads to fewer superbugs

Immune cells known as macrophages linked to growth of lymph vessels in eyes,

When it comes to heart disease women get worse treatment than men

Single molecular anchor holds the key to treating many types of bacterial meningitis

Phase II clinical study of ularitide

Benefits of starting CHF treatment with beta-blocker, bisoprolol

CT scans that detect calcium deposits in heart arteries can help predict the risk of coronary heart disease

World's largest study on acute coronary syndromes

Significant advance in the study of small ribonucleic acids

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

Immunosuppressive drug mycophenolate mofetil may be effective in controlling inflammatory eye diseases

Abstinence-only education can influence teen sexual behavior and beliefs

New key evidence supports claims that some types of cancer originate with defects in stem cells

Cochlear implants' performance not affected by amount of hearing loss in the implanted ear

Release of the neurotransmitter GABA halts stem cell production in the brain

Molecular switch that turns on the production of myelin

Potential new way to fight HIV

Study points to link to neurodegenerative disease target

Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

Attention doctors: Want patients to follow your advice? Treat them with dignity

PhD researcher at LifeArc

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