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Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents, compared with placebo, according to an article in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Incorporating human papillomavirus testing into cervical cancer screening will provide health benefits at a reasonable cost

Incorporating testing for human papillomavirus (HPV) DNA into cervical cancer screening has the potential for improving health benefits at a reasonable cost in France, Italy, the Netherlands, and the United Kingdom, according to a new study in the June 15 issue of the Journal of the National Cancer Institute.

14 Jun 2005

Continuous drinking for as little as eight weeks affects learning and memory up to 12 weeks later

Rodent studies, for example, have shown that chronic alcohol consumption for six months or more can produce permanent deficits and neural damage. A rodent study in the June issue of Alcoholism: Clinical & Experimental Research is the first to show that continuous drinking for as little as eight weeks can produce deficits in learning and memory that last up to 12 weeks after drinking stopped.

14 Jun 2005

Drinking during pregnancy can increase the risk of infection in newborns

Despite public-information campaigns and physician advice about alcohol consumption during pregnancy, between 15 and 25 percent of pregnant women continue to drink each month, and five to 10 out of 1,000 pregnant women drink an average of seven or more drinks per week.

14 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

Even though previous research has shown that fatty acids from fish oil reduce the risk of sudden cardiac death, patients with implantable defibrillators who took fish oil supplements did not see a reduction in serious heart rhythm abnormalities, according to a study in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Study reveals benefits of using insulin earlier

Results of an all-Canadian study announced June 13 at an international diabetes congress demonstrate that patients with type 2 diabetes can safely achieve target blood sugar (glycemic) levels faster and more frequently when insulin glargine (a basal, long-acting insulin) is added to therapy, versus using oral agents alone.

14 Jun 2005

'Hazardous' drinking and drug use are much less severe but much more common than dependence

Research has found that individuals with alcohol and drug dependencies have a greater occurrence of injuries, hypertension, HIV, hepatitis, acid-related peptic disorders, liver cirrhosis, depression, anxiety disorders, and major psychoses.

14 Jun 2005

Causes, consequences and clinical implications of alcohol-related brain shrinkage

Previous studies have demonstrated that the brains of alcoholics are smaller, lighter and "shrunken" when compared to nonalcoholic brains.

14 Jun 2005

New study supporting the importance of aggressive cholesterol-lowering

New clinical data shows that intensive cholesterol-lowering to targets below currently recommended levels significantly reduces the risk of heart attack and stroke for people with diabetes and heart disease.

14 Jun 2005

Combination of over-the-counter pharmacy drugs and prescription drugs dangerous

A British Medical Association (BMA) study is warning that combining over-the-counter pharmacy drugs with prescription medicine can be dangerous. The study authors say there is an over-use of pharmacy drugs as people try to manage their own health rather than going to a doctor.

14 Jun 2005

Viagra helps children with heart-lung condition achieve improved quality of life

Viagra, a drug originally developed to treat heart disease, and now more commonly used to treat impotence, may also help children with a serious heart-lung condition to walk further and breathe more easily.

14 Jun 2005

Doppler imaging provides better understanding of muscular dystrophy

A new study presented this week at the American Society of Echocardiography's 16th Annual Scientific Sessions offers new hope to children stricken with Duchene muscular dystrophy (DMD), a degenerative muscular disease characterized by a loss of voluntary muscle control which can eventually affect the heart.

14 Jun 2005

People who smoke or are obese are biologically older than slim individuals and non-smokers

Obesity and smoking are important risk factors for many age-related diseases. Tim Spector (St. Thomas’ Hospital, UK) and colleagues in the USA looked for evidence of ageing at a molecular level in smokers and obese individuals.

13 Jun 2005

Study examines reasons for unsatisfactory outcomes following deep brain stimulation surgery

A study of follow-up care for patients with unsatisfactory outcomes from deep brain stimulation (DBS) surgery for movement disorders offers insights into reasons for problems and proposes strategies for improved outcomes. The study will appear in the August print issue of Archives of Neurology.

13 Jun 2005

Drug Trial News

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

Incorporating human papillomavirus testing into cervical cancer screening will provide health benefits at a reasonable cost

Continuous drinking for as little as eight weeks affects learning and memory up to 12 weeks later

Drinking during pregnancy can increase the risk of infection in newborns

Two common gene variations are associated with the risk for developing chronic kidney disease

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

Study reveals benefits of using insulin earlier

'Hazardous' drinking and drug use are much less severe but much more common than dependence

Causes, consequences and clinical implications of alcohol-related brain shrinkage

New study supporting the importance of aggressive cholesterol-lowering

Combination of over-the-counter pharmacy drugs and prescription drugs dangerous

Viagra helps children with heart-lung condition achieve improved quality of life

Doppler imaging provides better understanding of muscular dystrophy

People who smoke or are obese are biologically older than slim individuals and non-smokers

Study examines reasons for unsatisfactory outcomes following deep brain stimulation surgery

Homeless persons prefer more aggressive medical care than the physicians making decisions for them

Prognosis is good for people who have epilepsy surgery

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

Short-term use of CPAP therapy may protect against cardiovascular disease

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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