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Doctors and patients think differently about clinical trials

A survey of patients and physicians regarding clinical trials shows that doctors don't recognize the importance of side effects as a barrier for their patients in deciding about whether to undergo experimental therapy.

9 Jun 2005

Designed drug for combined hormone and chemotherapy treatment

The search for new drugs to fight cancer remains at the top of the to do list for pharmaceutical researchers. A recent variation is polymer chemotherapy agents, drugs that have been attached to a "backbone" of long chain molecules.

9 Jun 2005

Association between chronic cytomegalovirus (CMV) and frailty syndrome

Older women with chronic cytomegalovirus (CMV), a lifelong viral infection, were found to have more than triple the risk of being frail than those who did not have the infection, as reported in the Journal of the American Geriatrics Society. This is the first demonstration to show an association between CMV and frailty syndrome.

9 Jun 2005

Multisequential MRI approach improves heart inflammation diagnosis

A multisequential approach to cardiovascular magnetic resonance scans that highlight different aspects of heart structure and function may offer a better and safer way to identify potentially deadly inflammation of the heart muscle, according to a new study (PDF) in the June 7, 2005, issue of the Journal of the American College of Cardiology.

9 Jun 2005

Study raises questions about food products meant to block cholesterol absorption

Plant sterols, which are naturally found in many foods but are also added to some foods intended to inhibit cholesterol absorption, are present in artery plaques, according to a new study (PDF) in the June 7, 2005, issue of the Journal of the American College of Cardiology.

9 Jun 2005

MabThera highly effective in treating rheumatoid arthritis

Results from the DANCER study presented today revealed that MabThera significantly improves symptoms in heavily treated patients who are affected by moderate-to-severe rheumatoid arthritis (RA), a painful and debilitating disease of the joints.

9 Jun 2005

Modifying your salt intake has the potential to prevent exercise-induced asthma

An Indiana University professor may have uncovered the mechanisms by which high-salt diets can trigger exercise-induced asthma, offering the most complete picture to date of how dietary factors can both aggravate and alleviate the symptoms of this common condition.

9 Jun 2005

Rheumatoid arthritis costs more to business and industry than almost any other disease

Speaking at a rheumatology congress in Vienna today (Thursday 9 June), USA experts estimated that RA costs employers over $4,000 more per person, per year.

9 Jun 2005

Rituximab, used to treat rheumatoid arthritis (RA) is safe and effective

Professor Paul Emery from the University of Leeds in the UK led the DANCER study (Double blind placebo controlled dose ranging study), designed to confirm the efficacy of rituximab for the treatment of patients with active RA who have failed to improve on one or more disease modifying anti-rheumatic drugs (DMARDs).

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

Rituximab provides new hope for people with lupus

Rheumatologists at the Annual European Congress of Rheumatology in Vienna, Austria heard today (Thursday 9 June) that rituximab is the first drug in a quarter of a century that is making a real impact, and an alternative to previous standard treatments of high-dose steroids, and chemotherapy.

9 Jun 2005

Missing link between mothers' diets and obesity in kids

New work may have found the missing link between mothers' diets and obesity in kids. A study published in the June issue of Cell Metabolism suggests that a hormone may explain the connection between mothers who are poorly nourished and an increased risk of obesity in their children.

8 Jun 2005

Adults with diabetes at higher risk for cardiovascular problems due air pollution

Researchers from the Harvard School of Public Health and colleagues assessed the effect of high air pollution levels, specifically emissions from coal-burning power plants and diesel vehicles, on Boston-area adults with diabetes.

8 Jun 2005

CT screening lowers negative appendectomy rate from 20% to 3% at urban hospital

Five years ago, the negative appendectomy rate at Massachusetts General Hospital (MGH) in Boston was 20%, but since the advent of CT screening, it has dropped to 3%, say MGH researchers. The negative appendectomy rate measures how often patients with symptoms of appendicitis have their appendix removed and then are diagnosed as not having acute appendicitis.

8 Jun 2005

Study is the first to identify involvement of chromosome 21 in developmental regression autism

A new Cincinnati Children's Hospital Medical Center study links regions of two chromosomes to susceptibility for a type of autism characterized by regression in development. Developmental regression can include the loss of previously acquired language, social skills or both.

8 Jun 2005

African-American and Hispanic patients with diabete are less likely to get eye exams

African-American and Hispanic patients with diabete are less likely than white patients to get eye exams, flu shots or cholesterol tests as part of their diabetes prevention care, according to a new review of recent studies in the latest issue of American Journal of Managed Care.

8 Jun 2005