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Antimicrobials improperly used about 50% of the time

Antimicrobial medications intended to prevent surgical site infections are appropriately administered to patients (within one hour before incision) only 55.7 percent of the time, according to a study published in the February issue of Archives of Surgery.

21 Feb 2005

Bipolar disorder a common feature in urban primary care practice

According to a study in the February 23 issue of JAMA. Nearly 10 percent of patients screened at a general medicine clinic in an urban area were found to have a history of bipolar disorder.

21 Feb 2005

New compound, AMN107, 20 times more potent than Gleevec for chronic myelogenous leukemia treatment

A laboratory study led by researchers at Dana-Farber Cancer Institute has shown that a potent and highly selective therapy for chronic myelogenous leukemia (CML) may ultimately be more effective than Gleevec®, the current standard of care.

21 Feb 2005

Female sex hormones have a profound effect on susceptibility to the herpes simplex virus

Two McMaster University studies, to be published in the Journal of Virology, show that sex hormones have a profound effect on susceptibility of female mice to the herpes simplex virus, type 2 (HSV-2 ), one of the most common sexually transmitted diseases.

21 Feb 2005

Green tea protects livers

A new study investigating the effects of the major flavonoid component of green tea on hepatic steatosis (fatty liver) found that it significantly protected livers that suffered ischemia/reperfusion (I/R) injury in mice. I/R injury, which is caused by decreased blood flow, can lead to complications after liver transplantation.

20 Feb 2005

Biochemical marker aids prognosis in liver transplant patients

A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

20 Feb 2005

Prozac, Xenical and Meridia may help type 2 diabetes patients lose weight

Three commonly used drugs - Prozac, Xenical and Meridia - may help type 2 diabetes patients lose small amounts of weight, although long-term benefits are not clear, a new review of 22 studies suggests.

20 Feb 2005

Naltrexone helps alcoholics moderate their drinking

A little-known drug called naltrexone provides a “meaningful benefit” in helping alcoholics moderate their drinking, according to the latest review of evidence from 29 studies on four continents.

20 Feb 2005

Vaccine that boosts the immune response could improve the effect of conventional treatment for patients with chronic myeloid leukaemia

CML is caused by the breakage and swapping of chromosomes 9 and 22, which results in a shortened chromosome called the Philadelphia chromosome. Cells with the abnormal chromosome make a protein that encourages aberrant growth and division. Patients with CML can be treated with a drug called imatinib or interferon alfa.

20 Feb 2005

Boys who were taller between birth and 1 year earned more than their shorter peers later in life

Slow growth in the year after birth seems to signal poor economic prospects as an adult, suggests a study of 50 year old men in Archives of Disease in Childhood.

20 Feb 2005

Folic acid recommendations have had little impact on incidence of neural tube defects

Recommendations on use of folic acid consumption have had no detectable impact on the incidence of neural tube defects, according to an international study published on bmj.com.

20 Feb 2005

Antidepressant drugs may be associated with an increased risk of suicidal behaviour

Antidepressant drugs may be associated with an increased risk of suicidal behaviour, particularly in the early stages of treatment, shows new evidence in this week's BMJ.

20 Feb 2005

Studies reveal methods viruses use to sidestep immune system

A series of studies by researchers at UT Southwestern Medical Center sheds light on the mechanisms used by viruses to thwart a host's immune defenses and may aid in the development of more effective drugs to fight hepatitis C and West Nile viruses, as well as the flu and the common cold.

17 Feb 2005

Study aims to help heart patients adapt to implanted defibrillators

Professor Jane Irvine, of York University’s psychology department, is helping those heart patients who must use miniature implanted defibrillators to cope with the psychological stress caused by these devices. Implantable Cardioverter Defibrillators (ICDs) are programmed to electrically shock the heart in the event of a life threatening heart rhythm incident.

17 Feb 2005

Deaths from mesothelioma will peak within ten years in the UK

Deaths from mesothelioma, an asbestos-related lung cancer, will peak within ten years in the UK and then fall to a much lower level, according to new figures published in this week's British Journal of Cancer.

17 Feb 2005

Nonsurgical microspheres an option for liver cancer patients

A study in February’s Journal of Vascular and Interventional Radiology found that patients undergoing liver cancer treatment with Theraspheres?, radioactive microspheres containing Yittrium-90, can tolerate a 150 Gy single dose or 268 Gy repeated dose without risk of radiation-induced liver disease.

17 Feb 2005

Olmesartan improves blood supply to kidneys

How do medications that block the renin-angiotensin system (RAS blockers) work to protect against kidney disease in people with diabetes? At least partly by improving the blood supply to the kidneys, suggests a study in the April Journal of the American Society of Nephrology.

17 Feb 2005

Link between muscle movement and breathing rhythms may shed new light on SIDS and sleep apnea

Between 2,000 and 3,000 infant deaths each year are attributed to Sudden Infant Death Syndrome (SIDS), according to the American Academy of Pediatrics. In addition, approximately 12 million Americans suffer from sleep apnea, a respiratory ailment that can lead to death in some cases.

17 Feb 2005

Separating chromosomes improves genetic test results

A new process that helps unmask genetic mutations by separating chromosomes so they can be studied individually may improve the diagnostic yield of some genetic tests, according to findings of a Colon Cancer Family Registry study published today in the Journal of the American Medical Association.

16 Feb 2005

Blood tests improve within two weeks of quitting smoking

Long-term smokers who quit may benefit from almost immediate improvements in blood platelet function, which could potentially reduce their risk of heart attacks or strokes caused by blood clots, according to a new study in the Feb. 15, 2005 issue of the Journal of the American College of Cardiology.

16 Feb 2005