Drug Trial News

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Drug shows early promise in treating patients with small-cell lung cancer

An early round of clinical testing shows that users of Opdivo, a drug sanctioned for treatment of small-cell lung cancer, more than tripled their five-year survival rate beyond the statistical average.

20 Apr 2017

CIRM funds clinical study to test safety, efficacy of new retinitis pigmentosa treatment

Cell therapy company jCyte is launching a phase 2b clinical trial to test the safety and efficacy of its developmental retinitis pigmentosa (RP) treatment, jCell.

19 Apr 2017

Cannabidiol shows promise to reduce seizures for people with difficult-to-treat epilepsy

Taking cannabidiol may cut seizures in half for some children and adults with Lennox-Gastaut syndrome (LGS), a severe form of epilepsy, according to new information released today from a large scale controlled clinical study that will be presented at the American Academy of Neurology's 69th Annual Meeting in Boston, April 22 to 28, 2017.

19 Apr 2017

UTHealth participates in study to evaluate effectiveness of new injectable HIV medication

The HIV Prevention Trials Network, which includes McGovern Medical School at The University of Texas Health Science Center at Houston, has launched a study to evaluate whether a new injectable medication can work as well as an existing oral pill to safely protect against HIV among men who have sex with men (MSM) and transgender women (TGW) who have sex with men.

18 Apr 2017

New drug compound could cut number of hot flushes in menopausal women

Women plagued by frequent hot flushes during the menopause could cut the number of flushes by almost three-quarters, thanks to a new drug compound.

3 Apr 2017

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

The University of Miami Miller School of Medicine will soon begin one of the nation's first full-scale Zika vaccine clinical trials testing the National Institutes of Health's (NIH) experimental DNA-based vaccine.

31 Mar 2017

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Bayer today announced positive data on its investigational compound copanlisib, an intravenous pan-Class I phosphatidylinositol-3-kinase (PI3K) inhibitor with predominant inhibitory activity against PI3K-α and PI3K-δ isoforms.

31 Mar 2017

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Novocure announced today results from the second cohort of its phase 2 pilot PANOVA trial studying Tumor Treating Fields (TTFields) in combination with nab-paclitaxel and gemcitabine for the treatment of advanced pancreatic cancer.

31 Mar 2017

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Novocure announced today results from its phase 2 pilot INNOVATE trial studying Tumor Treating Fields (TTFields) in combination with weekly paclitaxel for the treatment of recurrent ovarian cancer.

31 Mar 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

Clinical research trial investigates new treatment approach for early-stage eye melanoma

A first-of-its-kind, potentially groundbreaking new option for treating a form of eye cancer is now in its first phase-1 clinical research trial at Wills Eye Hospital in Philadelphia.

30 Mar 2017

Study explores new immunotherapy combinations to treat prostate cancer

Prostate cancer, notoriously resistant to immunotherapy due to its immunologically cool nature, triggers two pathways to chill an immune attack after one immunotherapy drug fires up the immune system, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

29 Mar 2017

SNIFF study to examine safety, efficacy of nasal insulin for treating Alzheimer’s disease

Can insulin, the hormone used for nearly a century to treat diabetes, improve cognition, memory and daily function in people with mild cognitive impairment or mild dementia due to Alzheimer's disease? Rush University Medical Center is testing this innovative potential treatment as part of a new nationwide study.

25 Mar 2017

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

22 Mar 2017

First-in-human study shows positive results for new medicine that could reduce maternal deaths

The Monash University Institute of Pharmaceutical Sciences today announced positive results from a first-in-human study of a new, inhaled form of a medicine that could significantly reduce maternal deaths around the world.

21 Mar 2017

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

Supplemental use of vitamin E and selenium did not forestall dementia, study finds

Antioxidant supplements vitamin E and selenium - taken alone or in combination - did not prevent dementia in asymptomatic older men, according to a study published online by JAMA Neurology.

20 Mar 2017

Novel synthetic HDL-C injection shows no benefit on arterial plaques

Injection of a novel form of synthetic high-density lipoprotein cholesterol (HDL-C), or good cholesterol, into the arteries of patients who had recently had a heart attack did not reduce the volume of fatty deposits, or plaque, in the arteries, compared with placebo injections, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

A two-vaccine regimen intended to protect against Ebola virus disease induced an immune response that persisted for approximately one year in healthy adult volunteers, according to results from a Phase 1 clinical trial published in the March 14th issue of the Journal of the American Medical Association.

15 Mar 2017

Drug Trial News

Drug shows early promise in treating patients with small-cell lung cancer

CIRM funds clinical study to test safety, efficacy of new retinitis pigmentosa treatment

Cannabidiol shows promise to reduce seizures for people with difficult-to-treat epilepsy

UTHealth participates in study to evaluate effectiveness of new injectable HIV medication

New drug compound could cut number of hot flushes in menopausal women

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

Clinical research trial investigates new treatment approach for early-stage eye melanoma

Study explores new immunotherapy combinations to treat prostate cancer

SNIFF study to examine safety, efficacy of nasal insulin for treating Alzheimer’s disease

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

First-in-human study shows positive results for new medicine that could reduce maternal deaths

New gene-silencing drugs cut cholesterol levels by half in early research

Supplemental use of vitamin E and selenium did not forestall dementia, study finds

Novel synthetic HDL-C injection shows no benefit on arterial plaques

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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