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Study compares different types of moisturizers for children with eczema

The Best Emollients for Eczema trial has found that no one type of moisturizer is better than another. This study, the first in the world to directly compare different types of moisturizers, highlights the importance of patient education and choice when deciding which moisturizers to use for children with eczema.

26 May 2022

STIs could be prevented with a dose of doxycycline after unprotected sex

A significant proportion of bacterial sexually transmitted infections (STIs) - gonorrhea, chlamydia or syphilis - were prevented with a dose of doxycycline after unprotected sex, according to preliminary results of a clinical trial that closed early because it was very effective for men who have sex with men and transgender women who are living with HIV or are taking HIV pre-exposure prophylaxis (PrEP).

25 May 2022

Widely used Type 2 diabetes drug does not prevent breast cancer spread, landmark trial finds

A widely used and inexpensive Type 2 diabetes drug, once hoped to hold enormous promise in treating breast cancer, does not prevent or stop the spread of the most common forms of the disease, according to new findings.

24 May 2022

Improving Patient Recruitment for Clinical Trial Research

In this interview, we speak to Matt Walz, CEO of Trialbee, about the importance of improving patient recruitment and retention within clinical trials.

From Trialbee 23 May 2022

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

Results from a real-world study investigating safety and effectiveness of clopidogrel versus aspirin monotherapy beyond 12 months after PCI in high-risk patients during the chronic maintenance period.

20 May 2022

STOP-COVID19 trial: Brensocatib did not improve clinical status of patients with severe SARS-CoV-2 infection

Brensocatib did not improve the clinical status of patients hospitalized with severe SARS-CoV-2 infection in the double-blind randomized, placebo-controlled STOP-COVID19 multicenter clinical trial, according to research published at the ATS 2022 international conference.

18 May 2022

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference.

18 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

Age-associated muscle decline can start as early as 40 years old and there are currently no effective interventions to counteract it other than exercise.

17 May 2022

NAVIGATOR trial: Nearly half of asthma patients improved with tezepelumab treatment

A greater proportion of patients with severe, uncontrolled asthma had more significant clinical responses to tezepelumab than placebo, according to research published at the ATS 2022 international conference.

16 May 2022

Phase 1 clinical trial of vaccine for rare but deadly mosquito-borne viruses shows promising results

A vaccine for eastern equine encephalitis virus (EEEV), western equine encephalitis virus (WEEV), and Venezuelan equine encephalitis virus (VEEV) was found to be safe, well-tolerated and induced a neutralizing antibody response in adult volunteers, according to newly published results from a Phase 1 clinical trial.

12 May 2022

Remdesivir shows no significant effect on patients with COVID-19 in Solidarity trial

A recent study published in the journal The Lancet summarized the final results of the Solidarity trial which aimed at finding out which drugs were most effective at reducing the severity of the disease among hospitalized patients.

9 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

Study finds promising new treatment for patients with behavioral variant frontotemporal dementia

A Monash University led study has found a promising new treatment for patients with behavioural variant frontotemporal dementia, the second most common form of dementia in the under 60s – resulting in a stabilising of what would normally be escalating behavioural issues, and a slowing of brain shrinkage due to the disease.

6 May 2022

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial to evaluate an investigational preventative vaccine for Epstein-Barr virus (EBV).

6 May 2022

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early-stage Dupuytren's disease.

30 Apr 2022

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did not significantly reduce patients' risk of organ failure, kidney problems, or death compared with placebo, although numerically fewer participants treated with dapagliflozin experienced these outcomes. The findings are published in CJASN.

29 Apr 2022

Phase I/II trials of new paratyphoid vaccine begin in Oxford

The University of Oxford in collaboration with the University of Maryland School of Medicine has begun recruiting for a Phase I/II trial of a new paratyphoid vaccine in human volunteers in Oxford - with first vaccinations taking place today (Tuesday).

26 Apr 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

New data may change the standard of care for patients with advanced non-small cell lung cancer

The phase 2 clinical trial of a multi-center study known as the COAST clinical trial has demonstrated improved outcomes using immunotherapy combinations for patients with unresectable stage III non-small cell lung cancer, according to researchers at Yale Cancer Center and participating organizations.

25 Apr 2022

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Drug Trial News

Study compares different types of moisturizers for children with eczema

STIs could be prevented with a dose of doxycycline after unprotected sex

Widely used Type 2 diabetes drug does not prevent breast cancer spread, landmark trial finds

Improving Patient Recruitment for Clinical Trial Research

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

STOP-COVID19 trial: Brensocatib did not improve clinical status of patients with severe SARS-CoV-2 infection

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

NAVIGATOR trial: Nearly half of asthma patients improved with tezepelumab treatment

Phase 1 clinical trial of vaccine for rare but deadly mosquito-borne viruses shows promising results

Remdesivir shows no significant effect on patients with COVID-19 in Solidarity trial

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

Study finds promising new treatment for patients with behavioral variant frontotemporal dementia

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

Phase I/II trials of new paratyphoid vaccine begin in Oxford

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

New data may change the standard of care for patients with advanced non-small cell lung cancer

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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