Drug Trial News

RSS

Chronic disease management: Does it improve health and save money?

A study published in the May/June issue of Health Affairs reports on the first randomized trial providing a scientifically valid look at what one might expect from chronic disease management programs that serve low-income individuals. The study result provides good news for state Medicaid leaders struggling to meet the needs of individuals with chronic conditions and also suggests that some disease management efforts, even among relatively low-risk patients, may be an effective strategy.

13 May 2008

Beta blockers after surgery more risky than beneficial

The results of new research has shown that patients given high doses of beta blocker drugs following non-cardiac surgery were more likely to have a stroke or die. However they were less likely to suffer a heart attack.

13 May 2008

Study shows how T cell's machinery dials down autoimmunity

A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust their function with exquisite precision. Such subtle adjustment enables T cells to modulate their development and function, including avoiding autoimmunity

12 May 2008

Arsenic-based agent shown to help eradicate leukemia-initiating cells

In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. Known as either cancer initiating cells (CICs) or leukemia initiating cells (LICs), these stealth populations are impervious to conventional chemotherapy and undaunted by targeted cancer therapies. When a leukemia patient relapses following a period of remission, it is the LICs that bear responsibility for the disease's reemergence.

12 May 2008

Study looks at phantom limb syndrome

Losing a limb can be a traumatic experience and, in some cases, emotional and physical pain can linger for years. To better understand the phenomenon, dubbed "phantom limb syndrome," Université de Montreal graduate student Emma Duerden is inviting amputees to come forward and share their experiences for a major study.

12 May 2008

Molecular pathway in muscle helps explain effectiveness of diabetes interventions

Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), demonstrate for the first time in a mouse model that skeletal muscle cells cultured in a low-calorie environment refrain from differentiating, an energy-demanding process by which cells mature and specialize.

12 May 2008

Starpharma reports positive VivaGel clinical study results

Starpharma Holdings Limited today announced positive results of a clinical trial that achieved all its objectives demonstrating that 3% SPL7013 Gel (VivaGel) was safe and well-tolerated in sexually abstinent women when administered vaginally, twice daily for 14 days.

11 May 2008

Discovery of ten new genes related to human growth

Scientists are beginning to unravel the question why people distinctly vary in size. In cooperation with scientists of the HelmholtzZentrum Munchen, an international genome-wide study has discovered ten new genes that influence body height and thus provides new insights into biological pathways that are important for human growth.

11 May 2008

Is divorce bad for the parents?

The elderly are cared for by their adult children regardless of their marital status. In a unique study funded by the Economic and Social Research Council, researchers found British adult children help their elderly parents according to current need (i.e. health) rather than past behaviour. This contrasts with other countries such as the US, where parents with a history of divorce see less of their children and receive less help from them.

11 May 2008

Binge drinking and driving

While many people believe that alcohol-impaired (AI) drivers are usually alcoholics, in fact, 80 percent of AI incidents are caused by binge drinkers. A recent study conducted among college students has found that binge drinkers, even when legally intoxicated, nonetheless believe they having adequate driving abilities.

11 May 2008

Researchers launch lung cancer screening trial

Scientists are testing a new way of detecting lung cancer at an early stage in people at greatest risk of developing the disease.

9 May 2008

University of Leicester to lead audit of adults with autism

The University of Leicester is leading on a national study to calculate the number of adults with autism, it has been announced today.

9 May 2008

Link found between birth order and asthma symptoms

Among four year-olds attending Head Start programs in New York City, those who had older siblings were more likely to experience respiratory symptoms including an episode of wheezing in the past year than those who were oldest or only children.

9 May 2008

Study affirms effectiveness of medication for juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis (JRA) is a chronic autoimmune disease that strikes children between the ages of newborn to 16 years. All children with JRA have joint pain, stiffness, and swelling and some also have fever and skin rashes.

9 May 2008

Young people are drinking and taking drugs to enhance sexual arousal or prolong sex

Teenagers and young adults across Europe drink and take drugs as part of deliberate sexual strategies. Findings published in BioMed Central's open access journal, BMC Public Health, reveal that a third of 16-35 year old males and a quarter of females surveyed are drinking alcohol to increase their chances of sex, while cocaine, ecstasy and cannabis are intentionally used to enhance sexual arousal or prolong sex.

9 May 2008

GeoVax Labs to launch phase II trials of HIV vaccine candidate

The Atlanta-based biotechnology firm GeoVax Labs plans to launch Phase II clinical trials of its experimental HIV vaccine this summer, company officials recently announced, the Atlanta Journal-Constitution reports (Hendrick, Atlanta Journal-Constitution, 5/8).

8 May 2008

Outcomes of obese and nonobese patients undergoing revision total hip arthroplasty

Along with age and injuries, obesity is a leading risk factor for osteoarthritis (OA), a painful and disabling joint disease. While excessive weight can aggravate the toll on almost any joint, obesity has been associated with a higher prevalence of hip OA and an increase in total hip arthroplasty (THA).

8 May 2008

Study finds darapladib lowers biomarker for cardiovascular problems

Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and block blood flow. The drug darapladib may offer a way to fight that risk, according to new research led by the University of Pennsylvania School of Medicine.

8 May 2008

Study finds arthritis can be a barrier for adults seeking to manage diabetes through exercise

More than half of adults with diagnosed diabetes also have arthritis, a painful condition that can be a barrier to physical activity -- an important health strategy for managing diabetes, according to a study released by the Centers for Disease Control and Prevention in today's Morbidity and Mortality Weekly Report.

8 May 2008