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Parkinson's disease linked to exposure to pesticides

Recent research suggests a possible link between exposure to pesticides and the development of Parkinson's disease (PD).

21 Apr 2008

Genentech updates on phase III study of Avastin plus chemo in first-line, advanced, non-squamous, non-small cell lung cancer

Genentech, Inc. has announced an update for the previously reported Roche-sponsored international Phase III clinical study (AVAiL) of Avastin (bevacizumab) in combination with gemcitabine and cisplatin chemotherapy, in patients with advanced, non-squamous, non-small cell lung cancer (NSCLC).

21 Apr 2008

Obesity, inactivity as common among cancer survivors as rest of Canadians

New research supported by the Canadian Cancer Society shows that many cancer survivors in Canada are overweight and inactive, which could put them at risk for health problems, including their cancer returning.

21 Apr 2008

Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?

In a definitive critical review, scientists at Children's Hospital & Research Center Oakland ask whether there is convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction.

21 Apr 2008

Physical activity and obesity in Canadian cancer survivors

A new study reveals that many cancer survivors are inactive and obese, which may negatively affect the control of their disease.

21 Apr 2008

The limits of observational data in determining outcomes from cancer therapy

Certain biases may exist in observational studies that compare outcomes of different cancer therapies, making the results questionable.

21 Apr 2008

Experts say naltrexone implants for drug dependency are risky

Experts in Australia say the use of naltrexone implants to treat drug dependency should be stopped because of a number of reports of severe adverse reactions.

20 Apr 2008

Trouble at mill will keep you awake at night

Workers who suspect that it is long hours, night shifts and job insecurity which makes them lose sleep could it seems be wrong.

20 Apr 2008

Experimental study on most common form of heart valve disease in Western countries may lead to new treatments

A team of scientists from the University of Montreal and the Montreal Heart Institute Research Centre, led by Dr. Jean-Claude Tardif, has completed an important study that show how a new type of medication can lead to an improvement in the aortic valve narrowing

18 Apr 2008

Iron nanoparticles spot tumor spread in patients with kidney cancer

Iron nanoparticles designed to collect in lymph nodes containing metastatic cancer cells have proven that they can help physicians detect metastatic spread of prostate cancer.

18 Apr 2008

Countries could save millions of Euros a year if follow-ups for breast cancer patients were led by specialist nurses rather than physicians

Follow-up care for breast cancer patients costs less if it is conducted by nurses rather than physicians, yet there is no difference in the patients' anxiety, depression, satisfaction or outcome, according to research presented today (Friday) at the 6th European Breast Cancer Conference (EBCC-6) in Berlin.

18 Apr 2008

Inhibiting stress oxidant may be new therapy for COPD

The study "Oxidative Stress is an Important Component of Airway Inflammation in Mice Exposed to Cigarette Smoke or Lipopolysaccharide" investigates the inflammatory responses in oxidative stress-deficient mice exposed to cigarette smoke.

18 Apr 2008

Herceptin and chemotherapy improves response rates without major adverse effects in HER2 breast cancer

Women with a particularly aggressive form of breast cancer seem to do better if they are treated with a combined anthracycline and taxane chemotherapy regimen before surgery, together with trastuzumab (Herceptin) before and after surgery, according to results from the largest multi-centre trial to investigate this treatment.

18 Apr 2008

First functional insulin-binding protein in invertebrates

Insulin-like growth factor (IGF) signaling that helps to regulate mammals' growth, metabolism, reproduction and longevity is well documented. Now research published in the open access journal Journal of Biology describes the genetic identification of the first functional insulin-like growth factor binding protein (IGFBP) ortholog in invertebrates.

17 Apr 2008

Naftidrofuryl for leg pain

Patients with pain caused by narrowed arteries in their legs have 37% more pain-free walking if they take naftidrofuryl (200mg three times a day) than those taking placebos, a Cochrane Review has found.

17 Apr 2008

Heparin versus placebo for acute coronary syndromes

Compared with those on placebos, giving heparin to people who have heart conditions like unstable angina and some forms of heart attack reduces the risk of having another heart attack, concluded a Cochrane Systematic Review.

17 Apr 2008

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

Many people take antioxidants in the belief that they will prolong their life expectancy. However, data from 67 randomised trials that involved just under a quarter of a million people failed to support this idea, a Cochrane Systematic Review has discovered.

17 Apr 2008

Huperzine A for Alzheimer's disease

Existing evidence suggests that patients with Alzheimer’s disease who have taken Huperzine A have improved general cognitive function, global clinical status, functional performance and reduced behavioural disturbance compared to patients taking placebos.

17 Apr 2008

Dopamine agonists reduce motor complications in Parkinson's disease, but increase other side-effects

Dopamine agonists are increasingly used to treat people with Parkinson's disease, but there is a debate about how well they work.

17 Apr 2008

Five-alpha-reductase Inhibitors for prostate cancer prevention

Compared to placebo treatment, taking 5-alpha-reductase inhibitors (5-ARIs) can reduce a man's risk of being diagnosed with prostate cancer from around 5-9% to around 4-6% during up to 7 years of treatment, according to a new Cochrane Review.

17 Apr 2008