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Volunteers can now register for coronavirus disease vaccine trials

In an attempt to recruit many volunteers, the National Institute of Allergy and Infectious Diseases (NIAID) has established a new clinical COVID-19 Prevention Trials Network (COVPN) that aims to enroll thousands of volunteers to test various investigational vaccines against the SARS-CoV-2 infection.

10 Jul 2020

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

Sheba Medical Center at Tel HaShomer and Immunicom, Inc. are initiating a ground-breaking clinical trial to evaluate the clinical effectiveness of the Immunicom LW-02 plasma filtration device as a monotherapy and in combination with an anti-PD-1 immune checkpoint inhibitor.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

NIH establishes a unified clinical trial network for testing COVID-19 vaccines

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has established a new clinical trials network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

8 Jul 2020

Cocktail of chemotherapy drugs may be safe, effective for patients with metastatic pancreatic cancer

Pancreatic cancer carries a poor prognosis, and it often goes undetected until advanced stages. A new BJS (British Journal of Surgery) study indicates that a certain cocktail of chemotherapy drugs may be a safe and effective treatment option for patients with a metastatic form of the disease.

8 Jul 2020

OpSec introduces COVID-19 testing kit authentication and traceability solution

OpSec Security, the global leader in physical and digital anti-counterfeiting and brand protection solutions, announces a COVID-19 testing kit authentication and traceability solution.

8 Jul 2020

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

The University of Liverpool, Liverpool School of Tropical Medicine and Southampton Clinical Trials Unit announced this week that they have launched their innovative COVID-19 drug testing platform, AGILE.

8 Jul 2020

QUT and Oxford collaborate on clinical trial to test asthma inhalers as treatment for COVID-19

QUT researchers are collaborating with colleagues at the University of Oxford on a UK clinical trial to test common asthma inhalers as a treatment for COVID-19 infection.

8 Jul 2020

Asthma inhalers being trialed for treatment of COVID-19

Researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection.

7 Jul 2020

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men who have sex with men and transgender women who have sex with men in a clinical trial sponsored by the National Institutes of Health.

7 Jul 2020

Dutch trial of convalescent plasma in COVID-19 discontinued

Now, a recent trial published on the preprint server medRxiv* in July 2020 reports that a majority of hospitalized COVID-19 patients have a high titer of neutralizing antibodies, at the time of admission, within 10 days of symptomatic disease.

7 Jul 2020

Human trials of potential COVID-19 vaccine commence in South Australia

A potential COVID-19 vaccine developed at Flinders University has commenced human trials in South Australia.

6 Jul 2020

Oxford COVID-19 vaccine trials move to stage 3 human trials

The technical name of the vaccine is ChAdOx1 nCoV-19 (AZD1222), as it is made from a virus called ChAdOx1, which is a weakened and non-replicating version of a common cold virus (adenovirus). The vaccine has been engineered to express the SARS-CoV-2 spike protein.

5 Jul 2020

New editorial published following adverse events of gene therapy clinical trial

The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted gene therapy clinical trial.

3 Jul 2020

Pfizer/BioNTech COVID-19 vaccine shows promise - virus neutralizing antibodies achieved

In a recent medRxiv* paper, a research group from the U.S. and Germany showed a robust immunogenic response and a promising safety profile of the novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) – actively encouraging its accelerated clinical development and potential rapid production.

2 Jul 2020

Common chemotherapy drug may be less effective in overweight, obese breast cancer patients

Breast cancer patients who are overweight or obese might benefit less from treatment with docetaxel, a common chemotherapy drug, than lean patients.

2 Jul 2020

Novavax SARS-CoV-2 vaccine candidate shows promise in animal models

A new study published on the preprint server bioRxiv in June 2020 shows that a candidate spike protein vaccine can induce neutralizing antibodies, antiviral T cell responses, and protection against infection.

2 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

RCSI begins clinical trial of promising therapy for critically ill COVID-19 patients

Clinician scientists at RCSI University of Medicine and Health Sciences have begun a clinical trial of a promising therapy for critically ill COVID-19 patients in intensive care.

29 Jun 2020

Combination therapy improves survival rates for women with aggressive endometrial cancer

Yale Cancer Center scientists have found that combining the targeted drug trastuzumab with chemotherapy significantly improves survival rates for women with a rare, aggressive form of endometrial cancer.

29 Jun 2020

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Drug Trial News

Volunteers can now register for coronavirus disease vaccine trials

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

Experimental drug for rare ALS shows promise in early clinical trial

NIH establishes a unified clinical trial network for testing COVID-19 vaccines

Cocktail of chemotherapy drugs may be safe, effective for patients with metastatic pancreatic cancer

OpSec introduces COVID-19 testing kit authentication and traceability solution

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

QUT and Oxford collaborate on clinical trial to test asthma inhalers as treatment for COVID-19

Asthma inhalers being trialed for treatment of COVID-19

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

Dutch trial of convalescent plasma in COVID-19 discontinued

Human trials of potential COVID-19 vaccine commence in South Australia

Oxford COVID-19 vaccine trials move to stage 3 human trials

New editorial published following adverse events of gene therapy clinical trial

Pfizer/BioNTech COVID-19 vaccine shows promise - virus neutralizing antibodies achieved

Common chemotherapy drug may be less effective in overweight, obese breast cancer patients

Novavax SARS-CoV-2 vaccine candidate shows promise in animal models

Repurposed drug for acute lung injury in COVID-19

RCSI begins clinical trial of promising therapy for critically ill COVID-19 patients

Combination therapy improves survival rates for women with aggressive endometrial cancer

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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