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Paracetamol overdoses drop without package size legislation

The acetaminophen (paracetamol) overdose rate in Calgary, Canada dropped by over 40% in the decade to 2004, without a change to the smaller pack sizes that were credited with overdose reductions in the UK.

9 Jul 2007

How the HIV virus mutates to escape the body's immune system

A pioneering collaborative study has discovered how the HIV virus evades the human body's immune system.

9 Jul 2007

Discovery of enzyme critical in DNA replication

In this week's issue of Science, researchers from the National Institute of Environmental Health Sciences (NIEHS) and Umea University in Sweden report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays in replicating DNA in higher organisms such as yeast and perhaps even humans.

9 Jul 2007

People with damage to blood vessels in the brain more likely to develop Alzheimer's disease

A recent study in Journal of Neuroimaging suggests that cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease.

9 Jul 2007

QRISK score more accurate than Framingham or ASSIGN for heart attacks

A new score for predicting the risk of heart disease gives a more accurate measure of how many UK adults are at risk of developing the disease and which adults are most likely to benefit from treatment.

9 Jul 2007

Abiraterone reduces levels of prostate specific antigen

For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials.

9 Jul 2007

Exercise improves quality of life for seniors

A new study appearing in the Journal of the American Geriatrics Society compares the efficacy of three programs designed for reducing falls and improving quality-of-life among the elderly; education, home safety assessment and modification (HSAM) and exercise training.

9 Jul 2007

Chromosome disorders can arise when sex cells are formed

Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates.

9 Jul 2007

Orlistat weight loss drug points to new cancer treatments

Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments.

9 Jul 2007

Common genetic risk factor for multiple cancers identified

A study led by researchers at the Keck School of Medicine of the University of Southern California (USC) has found that one of seven genetic risk factors previously identified as increasing the probability of developing prostate cancer also increases the probability of developing colorectal cancer.

9 Jul 2007

Colesevelam HCl hits diabetes with one-two punch

Patients with type 2 diabetes may soon be able to control their glucose and their cholesterol levels with a single drug, according to a study led by Vivian A.

9 Jul 2007

Modified herpes simplex virus shows promise in early clinical trial

A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said at the ESMO Conference Lugano (ECLU), Switzerland.

9 Jul 2007

Chromosome linked to colorectal cancer identified

Researchers at the Ontario Institute for Cancer Research and Cancer Care Ontario have successfully identified a specific genetic variation on chromosome 8 that is associated with colorectal cancer.

9 Jul 2007

Trastuzumab and chemo improves survival in women with operable HER-2 positive breast cancer

A recent meta-analysis of five major breast cancer trials has confirmed that combination treatment with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer.

9 Jul 2007

New score for predicting the risk of heart disease

A new score for predicting the risk of heart disease gives a more accurate measure of how many UK adults are at risk of developing the disease - and which adults are most likely to benefit from treatment.

8 Jul 2007

Pre-exposure prophylaxis for HIV infection

Clinical trials of pre-exposure prophylaxis - that is giving anti-retroviral drugs to non-HIV-infected individuals to prevent them becoming infected - are exploring whether the approach could lead to a large decrease in transmission of the virus with few or no side effects.

8 Jul 2007

Darunavir-ritonavir shows benefits for patients with HIV

Darunavir-ritonavir should be considered as a treatment option across the range of treatment-experienced patients with HIV infection, conclude Jose Madruga (Centro de Referencia e Treinamento DST/AIDS, Sao Paulao, Brazil) and colleagues in an Article in this week's issue of The Lancet.

8 Jul 2007

Etravirine effective for HIV supression

Treatment with TMC125 (etravirine) leads to better virological suppression than placebo as part of antiretroviral therapy in patients with documented resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs), conclude two randomised trials in this week's issue of The Lancet.

8 Jul 2007

Organic tomatoes a better health option

According to a new study organic food may be a better health option after all.

8 Jul 2007

It may be 'altitude sickness' rather than jet lag but you still feel rotten

A study has revealed that many of the effects of long-distance flight which are usually put down to jet lag and fatigue, may in fact be altitude sickness.

5 Jul 2007