Drug Trial News

RSS

Medium-sized polyps yield significant number of advanced adenomas and cancer

According to a University of Pittsburgh-led study published in the December issue of Gastroenterology, medium-sized polyps found in the colon with flexible sigmoidoscopy and subsequently evaluated by full colonoscopy are associated with a significant number of advanced adenomas (high-risk polyps) and cancers.

2 Dec 2006

Human embryonic stem cells show potential in treating rats with Parkinson's symptoms

Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson's-like symptoms dramatically, but the treatment caused a significant problem - the appearance of brain tumors - that scientists are now working to solve.

2 Dec 2006

Guanfacine no more effective than a placebo

Guanfacine, a medication commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is no more effective than a placebo, according to a study led by researchers at the San Francisco VA Medical Center.

2 Dec 2006

Why COX-2 inhibitors such as Vioxx can cause heart attacks and strokes

COX-2 inhibitors are primarily used to treat pain in conditions such as arthritis. They work by blocking the COX-2 enzyme, which is expressed at sites of inflammation and underlies the production of hormones called prostaglandins which swell the joints and cause the feeling of pain.

2 Dec 2006

Interruptions in antiretroviral treatment increases risk of developing AIDS-related diseases

Interruptions in an HIV-positive person's antiretroviral treatment regimen can increase the risk of developing AIDS-related diseases and sometimes can be fatal, according to a study published Thursday in the New England Journal of Medicine, the Los Angeles Times reports.

2 Dec 2006

Some institutional review board members have ties to Rx, medical device firms

About 15% of institutional review board members, who are charged with deciding whether proposed clinical trials are ethical and safe, in the past year were asked to judge at least one proposal involving a drug or medical device company in which they have a financial stake or involving one of those company's competitors, according to a survey published in the New England Journal of Medicine

2 Dec 2006

Schizophrenia treatment with older, generic antipsychotics cheaper, as effective as treatment with newer drugs

Treating schizophrenia patients with older, less expensive antipsychotic drugs reduces overall treatment costs by up to 30% and produces no increase in side effects or decrease in effectiveness compared with newer, brand-name medications.

2 Dec 2006

Patients often do not understand usage instructions on prescription drug labels

For the study, Terry Davis of Louisiana State University and colleagues presented five common prescription drug labels to 395 low-income adults in Chicago, Ill.; Shreveport, La.; and Jackson, Miss., and asked them, "How would you take this medicine?" All participants spoke English and had no vision or hearing problems.

2 Dec 2006

High dopamine transporter levels not linked to attention-deficit hyperactivity disorder

Results from a brain-imaging study conducted at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease.

2 Dec 2006

Drug for shingles relieves spinal cord injury pain

Australian doctors have discovered that patients with spinal cord injuries with moderate to severe nerve pain, received relief from a drug usually given to alleviate diabetic nerve pain and the pain from shingles.

2 Dec 2006

Ecstasy harmful to the brain even in small doses

Dutch researchers have found that even a small amount of ecstasy can be harmful to the brain.

29 Nov 2006

Don't kid yourself by cutting down on cigarettes

According to new research smokers who believe they are reducing their risk for heart disease by cutting back on cigarettes, are kidding themselves.

28 Nov 2006

An aching back? Well don't sit up straight!

By using a new form of magnetic resonance imaging (MRI), Scottish and Canadian researchers have been able to show that sitting in an upright position places unnecessary strain on the back.

28 Nov 2006

Poor memory and slow reactions linked to heart attacks

According to British research, people with a below average mental agility are prone to heart attacks.

27 Nov 2006

Many cancer patients, family members cite positives in experience

Almost two out of three cancer patients and their families believe that "something good has come out of their experience," according to a recent telephone survey jointly conducted by USA Today, the Kaiser Family Foundation and the Harvard School of Public Health (Szabo, USA Today, 11/21).

23 Nov 2006