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Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

Long-term therapy with some antiepileptic drugs and antibiotics can cause osteomalacia, a condition marked by softening of the bones that is usually the result of vitamin D and calcium deficiency.

16 May 2006

Signaling pathways in immune cells may lead to novel HIV treatment

New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system.

16 May 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

Diabetes troubles Australia

The Australia-wide study was conducted by the International Diabetes Institute over the last 15 months and is the first to have measured how many new cases of these diseases occur in Australia annually.

16 May 2006

Low affinity analogs of thyrotropin-releasing hormone are super-agonists

Chemical knockoffs resembling a key thyroid-related hormone are, in certain cases, more effective than the real thing at activating the target receptor.

16 May 2006

BMI standards for younger adults may not be appropriate for people in their 80s and 90s

If you're more than 80 years old, carrying a few extra pounds might not be such a bad idea. In fact, it may be beneficial.

16 May 2006

Access to emergency hormonal contraception from community pharmacists and family planning clinics

Pharmacies who provide fast and convenient access to the morning-after pill could be helping to prevent 10 per cent more unwanted pregnancies, according to a study in the latest British Journal of Clinical Pharmacology.

16 May 2006

Exercise, diet may protect against colorectal cancer

Voluntary exercise and a restricted diet reduced the number and size of pre-cancerous polyps in the intestines of male mice and improved survival, according to a study by a University of Wisconsin-Madison research published in the journal Carcinogenesis.

16 May 2006

Full year of treatment with pyrimethamine and sulfadiazine helps infants and children with toxoplasmosis

The first long-term study shows that treatment with pyrimethamine and sulfadiazine (two anti-parasitic drugs) during the first year of life leads to a lasting reduction in brain and eye damage for children with congenital toxoplasmosis.

16 May 2006

Review identifies factors that influence patient treatment choice for localized prostate cancer

Variables that influence a patients' choice of treatment for localized prostate cancer (CaP) are identified in a literature review that is authored by Dr. Zeliadt and colleagues and appears in the on-line version of Cancer, 2006.

16 May 2006

A therapeutic method for failed bladder augmentation in children

This study by Vajda et al investigated the potential causes leading to the deterioration of a previously successful bladder augmentation. This study by Vajda et al investigated the potential causes leading to the deterioration of a previously successful bladder augmentation.

16 May 2006

Role of acetaminophen in acute myocardial infarction

Acetaminophen is safe to use as a pain reliever and fever reducer after a heart attack, but it does not protect the heart muscle, a new study using sheep and rabbits concluded.

16 May 2006

Experts say Vioxx poses risks long after patients stop taking it

According to a leading American cardiologist patients who have taken the drug Vioxx are still at high risk of heart attacks or strokes even after they stop taking the medication.

14 May 2006

Improving care for Alzheimer disease sufferers

Behavioral and psychological symptoms of dementia represent a major challenge in the care of older adults with Alzheimer disease.

12 May 2006

14 million Americans are visually impaired

A National Eye Institute (NEI) study has found that although 94 percent of Americans aged 12 and older have good vision, the remaining six percent, or 14 million, are visually impaired.

12 May 2006

Cancer-causing chemicals associated with tobacco smoke found in the urine of nearly half the babies of smoking parents

When mum or dad puffs on a cigarette, their infants may inhale the resulting second-hand smoke. Now, scientists have detected cancer-causing chemicals associated with tobacco smoke in the urine of nearly half the babies of smoking parents.

12 May 2006

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

15% of Asians living in New York City are chronically infected with hepatitis B virus

Chronic hepatitis B infection usually will lead to liver inflammation and can progress to cirrhosis and liver cancer. The reported infection rate is 35 times higher than the rate in the general U.S. population.

12 May 2006

Transitions to injecting drug use among noninjecting heroin users

In a study reported in the current issue of the Journal of Acquired Immune Deficiency Syndromes, scientists from the National Development and Research Institutes, Inc. (NDRI) report on a study of street-recruited heroin users in New York City, who were not injecting, to determine the incidence and predictors of making a transition to injecting.

11 May 2006

c-myc gene found to play role in immune system

c-myc, a gene commonly involved in cancer onset, has been found to have a role in the immune system's normal function according to a study published in Blood.

11 May 2006

Drug Trial News

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

Signaling pathways in immune cells may lead to novel HIV treatment

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Diabetes troubles Australia

Low affinity analogs of thyrotropin-releasing hormone are super-agonists

BMI standards for younger adults may not be appropriate for people in their 80s and 90s

Access to emergency hormonal contraception from community pharmacists and family planning clinics

Exercise, diet may protect against colorectal cancer

Full year of treatment with pyrimethamine and sulfadiazine helps infants and children with toxoplasmosis

Review identifies factors that influence patient treatment choice for localized prostate cancer

A therapeutic method for failed bladder augmentation in children

Role of acetaminophen in acute myocardial infarction

Experts say Vioxx poses risks long after patients stop taking it

Improving care for Alzheimer disease sufferers

14 million Americans are visually impaired

Cancer-causing chemicals associated with tobacco smoke found in the urine of nearly half the babies of smoking parents

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

15% of Asians living in New York City are chronically infected with hepatitis B virus

Transitions to injecting drug use among noninjecting heroin users

c-myc gene found to play role in immune system

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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