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Sunitinib malate shows promise against advanced form of lung cancer

Results of a multi-center clinical study of a drug currently approved for treatment of kidney cancer indicate that it may also be effective for people with recurrent and advanced lung cancer.

5 Jun 2006

Sunitinib malate drug shows significant benefits over standard treatment for advanced kidney cancer

According to a new study, the drug sunitinib malate (Sutent.) is more effective than the current standard cytokine treatment given as an initial therapy for patients with advanced kidney cancer, also known as metastatic renal cell carcinoma (mRCC).

5 Jun 2006

Trials funded by for-profit organizations more likely to report positive findings

Cardiovascular clinical trials published between 2000 and 2005 were significantly more likely to report positive findings if they were funded by for-profit organizations than those funded by not-for-profit organizations

5 Jun 2006

Taxotere combined with standard chemotherapy improves survival in advanced head and neck cancers

The addition of docetaxel (Taxotere) to an initial chemotherapy regimen for inoperable head and neck cancers reduced mortality by nearly 30 percent over three years following treatment compared to the standard two-drug combination.

5 Jun 2006

School-based obesity interventions may need to be tailored by gender

A study of 17,000 U.S. adolescents finds that black and Hispanic girls are less physically active than white girls, but that this difference is attributable to the schools they attend

5 Jun 2006

West Nile virus DNA vaccine shows promise in phase 1 trial

Vical Incorporated has announced that in a Phase 1 clinical trial, a West Nile virus (WNV) vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated

5 Jun 2006

HERA trial continues to demonstrate significant patient benefits from Herceptin

New 23-month follow-up data from HERA, one of the largest breast cancer trials ever carried out, show that Herceptin (trastuzumab) following standard chemotherapy significantly reduced the risk of death by 34% for women with early-stage HER2-positive breast cancer.

5 Jun 2006

New data show Enzastaurin's activity across multiple cancer cell lines

Eli Lilly and Company's enzastaurin, an investigational, multi-targeted therapy that is currently the focus of two global Phase III clinical trials, one for the treatment of glioblastoma and one in non-Hodgkin's lymphoma

5 Jun 2006

Female genital mutilation exposes women and babies to significant risk at childbirth

Women who have had Female Genital Mutilation (FGM) are significantly more likely to experience difficulties during childbirth and that their babies are more likely to die as a result of the practice.

4 Jun 2006

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

A recent Finnish study identifies a low-penetrance gene defect which predisposes carriers to intracranial tumors called pituitary adenomas. In particular individuals carrying the gene defect are susceptible to such tumors which secrete growth hormone.

1 Jun 2006

Single embryo transfer as successful as double transfer in older women

Research by fertility experts in Finland has demonstrated for the first time that in many cases transferring a single embryo to the womb in women undergoing IVF is just as likely to result in pregnancy and a live birth in those aged 36 to 39 as it is in younger women.

1 Jun 2006

New insights into how working memory works

Memory tests performed with amnesiacs have enabled researchers to refute a long-held belief in an essential difference between long-and short-term memories.

1 Jun 2006

Startling data about infection-induced amputation and diabetes

Persons with diabetes who develop an infection are at a 55-fold greater risk for hospitalization, and an alarming 154-fold greater risk for amputation.

1 Jun 2006

Gene variation linked to more severe Crohn's disease

Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease.

1 Jun 2006

Sex during pregnancy myth debunked

A new study debunks the widely held belief that engaging in sexual intercourse during the final weeks of pregnancy can hasten labor and delivery.

1 Jun 2006

Fatigue is a major problem after liver transplantation

A new study on fatigue experienced by patients after undergoing liver transplantation found that it is a major problem that does not tend to improve with the passage of time.

1 Jun 2006

Exposure to environmental estrogens during development of the prostate gland in the male fetus may lead to later prostate cancer risk

A study in the June 1 issue of Cancer Research presents the first evidence that exposure to low doses of environmental estrogens during development of the prostate gland in the male fetus may result in a predisposition to prostate cancer later in life.

1 Jun 2006

Breast radiation device associated with complications

Doctors in New England have discovered that patients receiving accelerated-partial breast radiation therapy using a balloon brachytherapy system after lumpectomy for breast cancer can develop seroma, the retaining of fluid, in their breast which can require aspiration or make monitoring them by physical exam more difficult.

1 Jun 2006

Trial success for fight against adolescent obesity

Initial health trials using psychotherapy to treat adolescent obesity have shown promising results.

1 Jun 2006

Naltrexone relief for Crohn's sufferers

Study suggests that a drug used to ease symptoms of alcohol and drug addiction may also bring relief to people with Crohn's disease, a chronic inflammatory disorder of the intestine that affects an estimated 500,000 Americans.

31 May 2006