Genomics

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Non-coding 'junk' DNA could potentially contribute to the development of cancer

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer.

19 Jul 2022

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia.

19 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Scientists manipulate good bacteria using CRISPR systems

New North Carolina State University research shows progress in gathering information on an important – yet difficult to characterize – human gut bacterium called Bifidobacterium, which is used in many probiotics that help maintain healthy microbiomes.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

WHO issues an urgent call to accelerate access to genomics in resource-poor countries

The World Health Organization (WHO) has issued an urgent call to accelerate access to genomics, especially in resource-poor countries, in a report that examines technology gaps and opportunities.

15 Jul 2022

Newly characterized stem cell self-renewal factor enables continuous sperm production

Unlike women, who are born with all the eggs they'll ever have, men can continue to produce sperm throughout their adult lives. To do so, they require a constant renewal of spermatogonial stem cells, which give rise to sperm.

15 Jul 2022

MINAR2 gene mutations cause progressive hearing loss

Researchers at the John T. Macdonald Department of Human Genetics and the John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families. The gene variation mostly affects the inner ear hair cells, which are critical to hearing.

14 Jul 2022

New high-throughput genomic array offers an in-depth view of the mouse epigenome

A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.

13 Jul 2022

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

The Office of Cancer Clinical Proteomics Research at the National Cancer Institute has awarded $4.2 million over five years to Mount Sinai researchers establishing a Proteogenomic Data Analysis Center to advance cancer research and treatments.

13 Jul 2022

Study reveals tiny gene fragments as crucial new players in retinal development and vision

Researchers at the Centre for Genomic Regulation in Barcelona reveal that Srrm3 is a master regulator gene crucial for the development of photoreceptors, cells in the back of the retina which capture and process light, sending signals to the brain that enable vision.

13 Jul 2022

Ancestral molecule from bacteria-like cells may offer evolutionary insight on sexual reproduction

A study from Karolinska Institutet in Sweden, among others, presents the theory that egg-sperm fusion, a crucial feature of sexual reproduction in plants and animals, may have originated from an ancient form of genetic exchange that involved the fusion of bacteria-like microorganisms called archaea.

12 Jul 2022

Study calls for more conservation efforts to preserve adaptive DNA diversity of dolphin populations

The first widespread census of the genetic diversity of common dolphin (Delphinus delphis) populations living along 3000km of Australia's southern coastline has raised key pointers for future conservation efforts.

12 Jul 2022

Researchers create a comprehensive map of how complex networks of genes function together

Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

11 Jul 2022

Newly-discovered historical information reveals that Mendel was decades ahead of his time

Gregor Mendel, the Moravian monk, was indeed "decades ahead of his time and truly deserves the title of 'founder of genetics.'" So concludes an international team of scientists as the 200th birthday of Mendel approaches on 20 July.

11 Jul 2022

Salk professor wins $2 million to gain better understanding of cassava genetics

Research Professor Todd Michael will receive nearly $2 million from the Bill & Melinda Gates Foundation to sequence the genomes of multiple lineages of the cassava plant, a large starchy root vegetable also known as yuca root consumed in more than 80 countries around the world.

8 Jul 2022

Genomics

Non-coding 'junk' DNA could potentially contribute to the development of cancer

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

Scientists manipulate good bacteria using CRISPR systems

Sex matters when it comes to immune responses to vaccines and viral infections

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

WHO issues an urgent call to accelerate access to genomics in resource-poor countries

Newly characterized stem cell self-renewal factor enables continuous sperm production

MINAR2 gene mutations cause progressive hearing loss

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

Study reveals tiny gene fragments as crucial new players in retinal development and vision

Ancestral molecule from bacteria-like cells may offer evolutionary insight on sexual reproduction

Study calls for more conservation efforts to preserve adaptive DNA diversity of dolphin populations

Researchers create a comprehensive map of how complex networks of genes function together

Newly-discovered historical information reveals that Mendel was decades ahead of his time

Salk professor wins $2 million to gain better understanding of cassava genetics

Revolutionary technology identifies molecular alterations in failing hearts at single-cell resolution

Researchers develop a modular software system for optimizing biological systems

Study illustrates how the use of whole exome sequencing can better predict treatment response

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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