Genomics

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Study uncovers 50 new genes for eye color

The genetics of human eye color is much more complex than previously thought, according to a new study published today.

11 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

RNA editing events influence gene expression and phenotypic manifestation

Combining computational mining of big data with experimental testing in the lab, researchers at Children's Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.

10 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

Project Helios launched to unlock new approaches in small molecule drug discovery

The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Orionis Biosciences today announced the launch of Project Helios, a research collaboration designed to unlock new drug development opportunities through genome-scale mapping of drug-target interactions.

9 Mar 2021

Cooperation between two key genes drives breast cancer growth

Cooperation is generally a good thing -- working together to reach a goal. But in the case of cancer, it can be detrimental. University of Cincinnati researchers have discovered that cooperation between two key genes drives cancer growth, spread and treatment resistance in one particularly aggressive type of breast cancer.

9 Mar 2021

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics.

9 Mar 2021

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.

8 Mar 2021

Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

8 Mar 2021

Genomic surveillance can help identify how SARS-CoV-2 spreads in care homes

Care homes are at high risk of experiencing outbreaks of COVID-19, the disease caused by SARS-CoV-2. Older people and those affected by heart disease, respiratory disease and type 2 diabetes - all of which increase with age - are at greatest risk of severe disease and even death, making the care home population especially vulnerable.

3 Mar 2021

New transcriptome‐based aging clock reads the biological age of an organism

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome.

3 Mar 2021

Beckman Coulter Life Sciences Debuts Biomek NGeniuS Workstation at AGBT

Celebrating more than 85 years of innovation, Beckman Coulter Life Sciences announces its newest automated liquid handler, the Biomek NGeniuS workstation, at the virtual Advances in Genome Biology and Technology (AGBT) General Meeting.

From Beckman Coulter Life Sciences - Flow Cytometry 3 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

Researchers make gametes from xenogenic mouse stem cells

Making gametes such as sperm and eggs from pluripotent stem cells, primitive cells that can make all the tissues, greatly contributes to efficient reproduction of livestock animals and future assisted reproductive medicine. Researchers pave the way to achieve this goal using a body of xenogenic animals.

2 Mar 2021

Study discovers similarities between the genetic bases of various eating disorders

Anorexia nervosa, bulimia nervosa and binge-eating disorder are the three main eating disorders that 4 out of in 10 individuals living in Western Europe will experience at some point in their lives.

1 Mar 2021

New method boosts research efforts to eradicate cancer at its source

A new method, described in a study published today in the journal Nature Communications, has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

1 Mar 2021

Genomic Data Commons offers the largest resource in cancer genomics

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

27 Feb 2021

Neanderthal-derived protein may protect against COVID-19 susceptibility and severity

Researchers at the Lady Davis Institute at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

26 Feb 2021

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

26 Feb 2021

Genomics

Study uncovers 50 new genes for eye color

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Study opens the door to new possibilities targeting telomeres to help treat cancer

RNA editing events influence gene expression and phenotypic manifestation

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

Project Helios launched to unlock new approaches in small molecule drug discovery

Cooperation between two key genes drives breast cancer growth

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Diphtheria is evolving to become antibiotic-resistant and could lead to vaccine escape

Immune cells in cerebrospinal fluid could be novel biomarkers of response to immune-based therapies

Genomic surveillance can help identify how SARS-CoV-2 spreads in care homes

New transcriptome‐based aging clock reads the biological age of an organism

Beckman Coulter Life Sciences Debuts Biomek NGeniuS Workstation at AGBT

Yale researchers identify multiple genes involved in suppression of axon regeneration

Researchers make gametes from xenogenic mouse stem cells

Study discovers similarities between the genetic bases of various eating disorders

New method boosts research efforts to eradicate cancer at its source

Genomic Data Commons offers the largest resource in cancer genomics

Neanderthal-derived protein may protect against COVID-19 susceptibility and severity

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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