Genomics

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New project develops more efficient treatment approaches for cardiovascular diseases

Within the framework of a European collaborative research project, Oliver Müller, professor at the Faculty of Medicine at Kiel University and Consultant at the Department of Internal Medicine III, University Medical Center Schleswig-Holstein, Campus Kiel, will receive 1.4 million Euros for the project "CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease".

21 Dec 2018

Elegant, low-cost approach enhances single-cell RNA sequencing

Droplet microfluidics has revolutionized single-cell RNA sequencing, offering a low-cost, high-throughput method for single-cell genomics. However, this method has been limited in its ability to capture complete RNA transcription information.

20 Dec 2018

Study lays foundation for addressing unresolved questions in human aging

Doctors have long observed that biological age and chronological age are not always one and the same. A 55-year-old may exhibit many signs of old age and have numerous age-related diseases, whereas an 80-year-old may be healthy and robust.

20 Dec 2018

New research collaboration launches first evolutionary study to explore origins of fish that walk

A new research collaboration with support from the National Science Foundation, or NSF, begins an unprecedented study of walking cavefish to better understand the "fin-to-limb" transition that enabled the first vertebrates to walk on land more than 350 million years ago.

20 Dec 2018

Scripps Research finds molecular cause of a group of rare autoimmune disorders

A team from Scripps Research has found a molecular cause of a group of rare autoimmune disorders in which the immune system attacks the body's own healthy cells.

20 Dec 2018

European scientists aim to identify causes of dementia

Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease, Parkinson disease and Down syndrome. This common symptom is one of the major causes of disability and dependency among older people.

19 Dec 2018

DNA “webs” shown to promote metastasis in ovarian cancer

Researchers have found that neutrophils cast DNA “webs” that aid the spread of ovarian cancer cells to new tissues (a process known as metastasis).

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Researchers have discovered that the ER translocation of MAPK leads to drug resistance in melanoma.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

Geneticists discover how sex-linked disorders arise

Researchers have discovered a regulatory gene carried on the Y chromosome that determines whether a baby will be male or female and the risk of disease.

14 Dec 2018

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.

14 Dec 2018

Researchers discover protein involved in nematode stress response

When humans experience stress, their inner turmoil may not be apparent to an outside observer. But many animals deal with stressful circumstances - overcrowded conditions, not enough food - by completely remodeling their bodies.

14 Dec 2018

Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros

Conventional immunological tests for tuberculosis in rhinoceros are substantially insecure and bear high risk of false negative or false positive diagnosis with sometimes fatal consequences for the animal.

13 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

New findings throw light on natural sex selection process

For nearly 100 years biologists have argued about how exactly natural selection can possibly work. If nature selects the individuals with the best genes then why aren't all organisms the same?

13 Dec 2018

New protein complex helps embryonic stem cells to maintain their indefinite potential

Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of tissue, they lose their unlimited potential.

12 Dec 2018

Specific class of biomarkers can accurately indicate the severity of cancer

A cancer diagnosis tells you that you have cancer, but how that cancer will progress is a terrifying uncertainty for most patients. Researchers at Cold Spring Harbor Laboratory have now identified a specific class of biomarkers that can tell a lot about how aggressive a patient's cancer will be.

11 Dec 2018

Research pinpoints two proteins involved in creation of stem cells

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

11 Dec 2018

Genomics

New project develops more efficient treatment approaches for cardiovascular diseases

Elegant, low-cost approach enhances single-cell RNA sequencing

Study lays foundation for addressing unresolved questions in human aging

New research collaboration launches first evolutionary study to explore origins of fish that walk

Scripps Research finds molecular cause of a group of rare autoimmune disorders

European scientists aim to identify causes of dementia

DNA “webs” shown to promote metastasis in ovarian cancer

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Researchers discover how MAPK translocation leads to drug resistance in melanoma

New genetic testing method increases the precision of biomarker analysis

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

Geneticists discover how sex-linked disorders arise

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Researchers discover protein involved in nematode stress response

Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros

New discovery will improve the safety and predictability of CRISPR

New findings throw light on natural sex selection process

New protein complex helps embryonic stem cells to maintain their indefinite potential

Specific class of biomarkers can accurately indicate the severity of cancer

Research pinpoints two proteins involved in creation of stem cells

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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