Genomics

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Research shows how cells rebuild nucleus, organize genome after division

University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide - a discovery which could have major implications for understanding cancer and degeneration.

4 Dec 2017

Genetics may affect how the body responds to a particular diet

We can add one more thing to the list of traits affected by genetics: how our bodies respond to a particular diet.

1 Dec 2017

New software could make real-time DNA-authentication a reality

In the science-fiction movie Gattaca, visitors only clear security if a blood test and readout of their genetic profile matches the sample on file. Now, cheap DNA sequencers and custom software could make real-time DNA-authentication a reality.

30 Nov 2017

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers from The Scripps Research Institute (TSRI) have designed a bacterium that incorporates two unnatural bases, called X and Y, into genes, in addition to the four natural DNA bases − G, C, A and T − that usually code for proteins.

30 Nov 2017

Researchers unlock genetic processes underlying cancer

For many, breast cancer is more than just a disease – it's personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

29 Nov 2017

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

The largest ever genetic study of mosquitoes reveals the movement of insecticide resistance between different regions of Africa and finds several rapidly evolving insecticide resistance genes. Reported today) in Nature, this genetic resource will be used to develop new tools for monitoring resistance and managing insecticide use, and for designing novel control methods.

29 Nov 2017

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity.

29 Nov 2017

New microscope optimized to perform studies using optogenetic techniques

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication.

29 Nov 2017

Specific gene expression patterns could be key to younger looking skin

Some individuals' skin appears more youthful than their chronologic age. Although many people try to achieve this with creams, lotions, injections, and surgeries, new research published in the Journal of the American Academy of Dermatology indicates that increased expression of certain genes may be the key to intrinsically younger looking - and younger behaving - skin.

29 Nov 2017

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

Studying the genetic code allows researchers to know whether some patients with neuropsychiatric disorders either have extra copies of the CHRNA7 gene or are missing copies. However, little was known about the functional consequences of this genetic imbalance in brain cells.

29 Nov 2017

New molecular taxonomy may lead to precision-medicine treatments for hair disorders

Two decades ago, oncologists realized that molecular biologists could see medically important differences between tumors that looked identical to pathologists.

28 Nov 2017

Johns Hopkins researchers crack key part of mystery surrounding proteins

What makes the body of a person or any other organism work can, for the most part, be summed up in a word: proteins.

28 Nov 2017

Researchers convert natural bacterial immune system into microscopic data recorder

Through a few clever molecular hacks, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.

23 Nov 2017

Leishmania genome study reveals the parasites adaptation to the environment

A new study, conducted by researchers from the Institut Pasteur in Paris and the Centre for Genomic Regulation (CRG) in Barcelona, have revealed that Leishmania adaptation is a consequence of reversible and frequent chromosomal amplifications.

23 Nov 2017

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

Leishmaniasis is an important human and veterinary disease caused by Leishmania parasites that affect 12 million people in over 98 endemic countries. The disease is now emerging in Europe due to climate change and massive population displacement.

23 Nov 2017

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

A new study conducted at the University of Freiburg suggests that three-dimensional (3D) folding of the DNA reorganizes itself during differentiation of pluripotent stem cells to cardiomyocytes.

22 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Genomics

Research shows how cells rebuild nucleus, organize genome after division

Genetics may affect how the body responds to a particular diet

New software could make real-time DNA-authentication a reality

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers unlock genetic processes underlying cancer

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

New microscope optimized to perform studies using optogenetic techniques

Specific gene expression patterns could be key to younger looking skin

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

New molecular taxonomy may lead to precision-medicine treatments for hair disorders

Johns Hopkins researchers crack key part of mystery surrounding proteins

Researchers convert natural bacterial immune system into microscopic data recorder

Leishmania genome study reveals the parasites adaptation to the environment

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

Study finds specific tumor environment that stimulates cancer cells to metastasize

Scientists develop new approach to combating antibiotic resistance

Research suggests genome's spatial organization as important switch for defining cell types

Scientists develop novel technology that uses CRISPR to map genetic mutations

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