Genomics

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Novel computer system can help inform future therapies for patients with inherited heart disease

An integrated, genomic computer system for precision cardiology has been created using clinical data that can help inform medical and surgical decisions to support future therapies for patients with inherited heart disease.

14 Jun 2021

Scientists develop new method for single-cell lineage tracing of metastatic cancer

It's often cancer's spread, not the original tumor, that poses the disease's most deadly risk.

10 Jun 2021

Researchers develop new method to make CRISPR gene editing more precise

CRISPR Researchers from Aarhus University and University of Copenhagen have developed a new method, which makes CRISPR gene editing more precise than conventional methods.

10 Jun 2021

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Humans have been plagued by a myriad of deadly cancers since ages. Parallelly, they have also been attempting different permutations and combinations of treatments to cure the disease. Part of these attempts involving biomolecular targets have come to the fore in recent years.

10 Jun 2021

Study reveals new insights into how genes are regulated in dementia

The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease.

10 Jun 2021

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD).

9 Jun 2021

Study shows that natural selection can reverse evolution through sexual selection

Natural selection can reverse evolution that occurs through sexual selection and this can lead to better females, new research shows.

9 Jun 2021

Researchers identify genomic cellular map associated with hippocampal sclerosis

A multidisciplinary team led by researchers from the Spanish Research Council identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy.

8 Jun 2021

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers from the Hong Kong University of Science and Technology and Beijing Tiantan Hospital have recently uncovered a new gene mutation responsible for the non-familial patients of cerebral cavernous malformation (CCM) - a brain vascular disorder which inflicted about 10~30 million people in the world.

8 Jun 2021

Researchers find new insight on the link between a gene and congenital heart disease

New insight on the link between a gene called SORBS2 and congenital heart disease has been published today in eLife, with findings that may help explain the cause of the disease in some patients.

8 Jun 2021

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

Travelers abroad may pick up bacteria and other vectors containing genes conferring antimicrobial resistance which remain in the gut when returning to their home country, according to a study published in Genome Medicine.

7 Jun 2021

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

A research group of the Department of Pharmacy and Biotechnology of the University of Bologna analyzed more than one million SARS-CoV-2 genome sequences.

5 Jun 2021

Study brings to light the role of a cellular protein in COVID-19 infections

Angiotensin-converting enzyme 2 (ACE2), a protein found on the surface of lung cells, facilitates the entry of the novel coronavirus into host cells.

4 Jun 2021

Study identifies new genetic variants that cause developmental disorders in children

Non-coding regions of DNA could hold the key to diagnosing developmental disorders in children, new research suggests.

4 Jun 2021

Predictive model detects patients who fit historical criteria for genetic testing

Patients who, perhaps unbeknownst to their health care providers, are in need of genetic testing for rare undiagnosed diseases can be identified en masse based on routine information in electronic health records (EHRs), a research team reported today in the journal Nature Medicine.

3 Jun 2021

Study shows how the physical nature of genome changes before and after cell differentiation

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Scientists develop new gene drive with a built-in genetic barrier

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

3 Jun 2021

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease.

2 Jun 2021

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Researchers at the University of Eastern Finland have uncovered potential mechanisms by which microRNAs (miRNA) drive atherogenesis in a cell-type-specific manner.

2 Jun 2021

Genomics

Novel computer system can help inform future therapies for patients with inherited heart disease

Scientists develop new method for single-cell lineage tracing of metastatic cancer

Researchers develop new method to make CRISPR gene editing more precise

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Study reveals new insights into how genes are regulated in dementia

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

Study shows that natural selection can reverse evolution through sexual selection

Researchers identify genomic cellular map associated with hippocampal sclerosis

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers find new insight on the link between a gene and congenital heart disease

International travelers may pick up destination-specific antimicrobial resistance genes, study reveals

SARS-CoV-2 genome analysis reveals new 'Mexican variant'

Study brings to light the role of a cellular protein in COVID-19 infections

Study identifies new genetic variants that cause developmental disorders in children

Predictive model detects patients who fit historical criteria for genetic testing

Study shows how the physical nature of genome changes before and after cell differentiation

Epigenetic regulation affects the 3D structure of genome

Scientists develop new gene drive with a built-in genetic barrier

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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