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Single-dose vaccination effective for healthcare workers with prior SARS-CoV-2 infection

The findings reveal that healthcare workers previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop significantly higher antibody titers in response to a single dose of COVID-19 vaccine, as compared to healthcare workers without prior SARS-CoV-s infection. The study is currently available on the medRxiv* preprint server.

2 Feb 2021

Survey: Half of the people with uncontrolled asthma smoke cannabis

As the number of states increase where medical and recreational cannabis use is legal, so does the importance that physicians discuss with patients the effects of cannabis on those with asthma.

2 Feb 2021

Reducing barriers in cancer care for LGBTQ2SPIA+ patients

In an upcoming issue of the Journal of Medical Imaging and Radiation Sciences, published by Elsevier, undergraduate researchers from the University of Alberta's Radiation Therapy Program in the Faculty of Medicine and Dentistry describe how LGBTQ2SPIA+ patients face unique cancer risks, including fear of discrimination, higher incidence of certain cancer sites, and lower screening rates, resulting in more cancers detected at later stages.

2 Feb 2021

Most of the telehealth appointments found to be audio-only visits

Telehealth use has surged during the pandemic at clinics that serve lower-income Americans, which allowed the clinics to maintain access to care at a time when many other health care organizations saw significant declines in utilization, according to a new RAND Corporation study.

2 Feb 2021

Study finds link between lack of ICU beds and patient mortality during COVID-19 pandemic

A new study by Yale researchers found a significant association between the availability of hospital resources -- particularly ICU beds -- and patient mortality during the early weeks of the COVID-19 pandemic.

2 Feb 2021

Regenstrief and Boomerang Ventures partner to expand the reach of healthcare innovations

Regenstrief Institute and Boomerang Ventures are announcing a partnership to develop and disseminate healthcare solutions to improve the well-being of people around the world.

2 Feb 2021

Study finds increased opioid consumption two years after intensive care

Nearly 11 percent of people admitted to an intensive care unit in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge.

2 Feb 2021

New guidance to provide mental health support for people with neurodegenerative conditions

Lancaster University together with the British Psychological Society has provided research-based recommendations for mental health support for people living with four motor neurodegenerative conditions.

2 Feb 2021

Simple soil remediation can save children from lead toxicity

Simple soil remediation can substantially reduce levels of the toxic metal lead in the blood of children living in heavily contaminated areas, says a new study conducted in Bangladesh.

2 Feb 2021

Delaying colonoscopy after an abnormal stool test can have major consequences

A new Veterans Affairs study finds that delays in undergoing colonoscopy following an abnormal stool test increase the risk of a colorectal cancer diagnosis and cancer-related death.

2 Feb 2021

Study shows safety and effectiveness of two recommended ICU sedatives

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.

2 Feb 2021

MCRI specialists create Australia's and New Zealand's first set of child head injury guidelines

Australia's and New Zealand's first set of clinical guidelines for children's head injuries has been created by a network of specialists based at the Murdoch Children's Research Institute.

2 Feb 2021

What is the structure and function of SARS-CoV-2’s D614G spike mutation?

A team of researchers use a computational approach to integrate available data D614G SARS-CoV-2 spike mutation, exploring its structure and molecular mechanisms.

2 Feb 2021

Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2

A new preprint reports the efficacy of two repurposed drugs that could be useful against SARS-CoV-2 when supplemented with zinc.

2 Feb 2021

Pfizer-BioNTech vaccine shows promise against new SARS-CoV-2 variants

A team of researchers in the U.S. studied the Pfizer-BioNTech vaccine candidate - currently being rolled out in many parts of the world to high-risk individuals - to see if it still holds up against mutant strains of the virus and yielded encouraging results.

2 Feb 2021

ACE2 agonist C21 relieves respiratory difficulty in COVID-19

A new study describes a pilot study on the efficacy of a molecule called C21, which enhances the activity of the angiotensin-converting enzyme 2 (ACE2), the host cell receptor that facilitates viral entry.

2 Feb 2021

Antiviral compound GC-376 shows efficacy against SARS-CoV-2 in vivo

Over the past months, many potential antivirals against SARS-CoV-2 have been identified as deserving further development to target several viral proteins. A new study deals with one such molecule, the viral main protease (Mpro) inhibitor GC-376, and describes its efficacy in inhibiting virus-host interaction.

2 Feb 2021

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Researchers have explored heritable factors, age and body mass on temperature variation between humans. One notable finding is that the current threshold for detecting fever in older adults may be too high, precluding the ability to detect COVID-19 early on

2 Feb 2021

Researchers develop new modeling to map SARS-CoV-2 transmission dynamics in UK

Using a modified version of the susceptible-infectious-recovered (SIR) model to include effects of prevention measures, researchers show patterns in the increase and decrease of coronavirus disease 2019 (COVID-19) cases in the UK.

2 Feb 2021