Histology & Microscopy

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New AI-based method of image analysis finds new cell types in tissue

In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala University researchers have now developed an entirely new method of image analysis.

19 Oct 2020

New revolutionary optical microscope for precise identification of tumors

The VIBRA project, "Very fast Imaging by Broadband coherent Raman", has just ended at the Politecnico di Milano.

16 Oct 2020

Introducing the OpenStand Motorized Optical Stand

Introducing the OpenStand Motorized Optical Stand, the latest from Prior Scientific

From Prior Scientific Instruments Ltd. 16 Oct 2020

NYU scientists develop a method using holographic imaging to detect viruses, antibodies

A team of New York University scientists has developed a method using holographic imaging to detect both viruses and antibodies. The breakthrough has the potential to aid in medical diagnoses and, specifically, those related to the COVID-19 pandemic.

13 Oct 2020

New approach to reveal high-resolution protein structural details

The number of proteins in the human body, collectively known as the proteome, is vast. Somewhere between 80,000 and 400,000 proteins circulate in our cells, tissues and organs, carrying out a broad range of duties essential for life.

6 Oct 2020

Planaria flatworm can be used as reliable alternative for testing topical skin products

Tests for skin treatments could be screened using flatworms rather than other animals such as rabbits, according to new research.

1 Oct 2020

Researchers identify 'social cells' in the brain linked to social behavior

A research team led by Professor TAKUMI Toru of Kobe University's Graduate School of Medicine (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) have identified 'social cells' in the brain that are related to social behavior. The cells were identified via Ca imaging conducted using a microendoscope .

1 Oct 2020

New framework allows researchers to probe the metabolic processes inside cancer cells

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer.

28 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

New device helps study the reaction of individual cells to mechanical stress

The behavior of cells is controlled by their environment. Besides biological factors or chemical substances, physical forces such as pressure or tension are also involved.

25 Sep 2020

Research sheds light on how membrane proteins could be influenced by lipid environments

The cell membrane, the wall-like boundary between the cell interior and its outside environment, is primarily made up of two kinds of biomolecules: lipids and proteins. Different

24 Sep 2020

Tobacco dependence treatment is critical to excellence in health care delivery

A UCLA-led report published today in the Journal of the American Medical Association Internal Medicine exposes what the authors call a weakness in the high-profile "Best Hospitals Honor Roll" published annually by U.S. News and World Report.

22 Sep 2020

New national research and training hub at UW-Madison could transform medicine

A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.

22 Sep 2020

PARP enzymes can bring two broken DNA ends together, shows study

Scientists at St. Jude Children's Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.

16 Sep 2020

Bacterial movement is powered by tiny protein motor

The ability to move is key for bacteria like some strains of salmonella and E. coli to efficiently spread infections. They can propel themselves forward using threads, known as flagella, powered by the flagellar rotary motor.

15 Sep 2020

3D cluster of cells could enhance myocardial repair

Cell therapy for cardiac regeneration, while promising, has been hampered by issues with long-term survival of the transplanted cells.

15 Sep 2020

New x-ray microscopy technique could help accelerate efforts to map neural circuits

One of the grand quests in neuroscience is to build a precise map of the brain, charting all its neurons and the connections between them. Such a wiring diagram, called a connectome, promises to help shed light on how a collection of cells can together give rise to thoughts, memories, behaviors and myriad other functions.

14 Sep 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020

Researchers develop 3D imaging technique to visualize damaged lung tissue after severe COVID-19

Physicists at the University of Göttingen, together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19.

21 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020