Histology & Microscopy

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Scientists solve first structure of human cotransporter protein KCC1

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles – ions – across the cell membrane.

29 Oct 2019

Shape of lung tissue fibers influences respiratory elasticity

Take a deep breath. Now exhale. Congratulations! You've just done something completely ordinary, yet so mysterious that scientists still don't know everything about it.

29 Oct 2019

Researchers use 3D electron microscopy to unravel dense networks in the cerebral cortex

Unlike any other organ, our brains contain extremely densely packed networks of membranous cables that are used by our about 86 billion nerve cells for communication amongst each other.

24 Oct 2019

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from the ocean.

21 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Salk scientists receive NIH funding to map brain circuitry for movement

A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping.

18 Oct 2019

Driving Adoption of Digital Pathology with Image Search

Driving adoption of digital pathology through the Scan Image Search from Huron Digital Pathology. Patrick Myles talks to the Dell Healthcare PowerChat Podcast.

From Huron Digital Pathology 1 Oct 2019

High-speed imaging technology reveals previously unseen details of living creatures

The Columbia team behind the revolutionary 3D SCAPE microscope announces today a new version of this high-speed imaging technology.

27 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

Researchers map and activate bacterial 'immune defense system'

With the aid of highly advanced microscopes and synchrotron sources, researchers from the University of Copenhagen have gained seminal insight into how bacteria function as defense mechanisms against attacks from other bacteria and viruses.

24 Sep 2019

Label-free laser microscopy technique accurately detects ovarian metastatic cancer

Women undergoing treatment for ovarian cancer are checked for tumor cells that may have spread to surrounding tissues, but current technologies miss very small metastatic areas. Now a laser microscopy technique is able to identify these regions with great accuracy.

17 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

HORIBA’s Yumizen hematology analyzers minimize microscopy slide reviews, improve diagnosis

HORIBA UK Ltd, Medical announces the publication of scientific studies which demonstrate the excellent performance of its new HELO high throughput fully automated haematology platform on body fluid and pathological samples.

From HORIBA Scientific UK 11 Sep 2019

Innovative method could improve understanding of many processes in the body at molecular level

Cells are the basic building blocks of life - and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century.

7 Sep 2019

Sensing temperature inside cells using a fluorescent nano-thermometer

How do you know a cell has a fever? Take its temperature.

23 Aug 2019

Using principles of mechanics and physics to identify state of individual cells

Researchers at the NYU Tandon School of Engineering have discovered a new way to identify the state of individual cells by bringing principles of mechanical engineering and physics to bear on processes that are now well understood at the macro level, but not yet at the cellular level: how stressors such as injury and disease force an organism into a new level of equilibrium -- a biological process of finding a "new normal" called allostasis.

20 Aug 2019

Olympus launches first Global Image of the Year Life Science Light Microscopy Award

Inspired by the beauty and breadth of images submitted for the 2018 Image of the Year Life Science Light Microscopy Award held in Europe, Olympus has launched its first Global Image of the Year Life Science Light Microscopy Award, recognizing the best in life science imaging worldwide.

From Evident Corporation - Life Sciences 8 Aug 2019

Japanese scientists develop new method to construct 3D models from 2D images

Japanese scientists report in Pattern Recognition a new method to construct 3D models from 2D images. The approach, which involves non-rigid registration with a blending of rigid transforms, overcomes several of the limitations in current methods.

6 Aug 2019

Thermo Fisher Scientific unveils new Krios solution at Microscopy and Microanalysis 2019

Today at Microscopy and Microanalysis 2019, Thermo Fisher Scientific unveiled a new Krios solution designed to break down the barriers to cryo-EM adoption through improved ease-of-use, faster results and the most compact 300kV cryo-EM microscope design on the market.

From Thermo Fisher Scientific – Electron Microscopy Solutions 6 Aug 2019

Automating cryo-EM sample preparation

SPT Labtech has today announced the introduction of chameleon, an industry-enabling sample-preparation system for cryo-EM.

From SPT Labtech 6 Aug 2019