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Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

Former diabetes drug may help in the treatment of breast cancer, study shows

Findings from a new study led by Yale Cancer Center show the small molecule inhibitor drug, PF05175157, originally developed to treat diabetes by Pfizer, may help in the treatment of breast cancer.

12 Dec 2021

Statistical models predict outcomes for patients receiving non-intensive AML therapy

An international team has developed statistical models to predict the risk of early death in patients being treated with non-intensive therapies for acute myeloid leukemia (AML).

12 Dec 2021

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

12 Dec 2021

Novel AI score predicts risk of death in patients with suspected or known coronary artery disease

A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide.

11 Dec 2021

Researchers discover why people with asthma have lower brain tumor risk

There's not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed.

11 Dec 2021

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

11 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care investigated whether nivolumab has an added benefit over watchful waiting in the adjuvant treatment of adults with carcinoma of the esophagus or the gastroesophageal junction and pathological residual disease after prior neoadjuvant chemoradiotherapy (CRT).

10 Dec 2021

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Despite preliminary supporting evidence that the dopaminergic agent bupropion might improve sexual desire for female cancer survivors, the NRG Oncology CC004 clinical trial determined that bupropion did not improve outcomes when compared to a placebo.

10 Dec 2021

Study finds sarbecoviruses circulating in wildlife outside Asia can infect human cells

A recent study tested the RBD of 2 sarbecoviruses found in Russian horseshoe bats and other clades 3 viruses for their ability to invade the human cell.

10 Dec 2021

Cardinal Health survey of oncologists shines light on mental health distress affecting cancer patients

More than 80% of oncologists frequently see mental health distress in their patients with cancer, and more than 90% say it has a significant impact on their health outcomes.

9 Dec 2021

Subcutaneous defibrillators equally effective in delivering electric shocks, study says

Electric shocks delivered by subcutaneous defibrillators are equally effective compared to shocks delivered by conventional transvenous defibrillators, according to a study published in the journal Circulation.

9 Dec 2021

Regular aerobic exercise during midlife may prevent age-related chronic diseases

Middle-aged endurance athletes have better control of blood pressure and higher arterial elasticity (a noninvasive measure of cardiovascular risk) than sedentary adults in the same age group.

9 Dec 2021

New consensus-based recommendations designed to improve quality of life for DMD patients

Many more adults with Duchenne muscular dystrophy (DMD) are living longer thanks to improvements in treatment, however international standards of care have not yet fully addressed the complex needs of these patients.

9 Dec 2021

Researchers explore role of FTO gene in the comorbidity of depression and obesity

Scientists from the University of Granada (UGR) have highlighted that the possible role attributed to the 'fat mass and obesity-associated' (FTO) gene in the comorbidity of depression and obesity can only be confirmed by conducting more studies involving individuals suffering from both diseases, together with more in-depth analysis of the different clinical subtypes of depression, as some are more prone to being accompanied by obesity than others.

9 Dec 2021

Booster vaccination can reduce breakthrough infection risk in HIV patients

New study reveals that people with HIV are at a high risk of breakthrough COVID-19 infection in comparison to people without HIV, and that booster vaccinations can be protective for those living with HIV.

9 Dec 2021

Study identifies the role of early developmental gene in intracranial aneurysms

Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.

9 Dec 2021

Medical Condition News

Novel immunotherapy shows promise for children, young adults with recurrent AML

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

Former diabetes drug may help in the treatment of breast cancer, study shows

Statistical models predict outcomes for patients receiving non-intensive AML therapy

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Novel AI score predicts risk of death in patients with suspected or known coronary artery disease

Researchers discover why people with asthma have lower brain tumor risk

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Study finds sarbecoviruses circulating in wildlife outside Asia can infect human cells

Cardinal Health survey of oncologists shines light on mental health distress affecting cancer patients

Subcutaneous defibrillators equally effective in delivering electric shocks, study says

Regular aerobic exercise during midlife may prevent age-related chronic diseases

New consensus-based recommendations designed to improve quality of life for DMD patients

Researchers explore role of FTO gene in the comorbidity of depression and obesity

Booster vaccination can reduce breakthrough infection risk in HIV patients

Study identifies the role of early developmental gene in intracranial aneurysms

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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