Medical Condition News

RSS

Study shows minimal lean muscle mass loss with GLP-1 and GLP-1/GIP therapy for weight loss

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that patients using GLP-1 or combined GLP-1 / GIP receptor agonist therapy for weight loss experienced minimal lean muscle mass loss as they lost weight across 6 months of treatment.

9 Apr 2025

Study explores impact of parental Alzheimer’s on tau protein spread in the brain

While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain that is a sign of the disease, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

UCLA study identifies key protein driving kidney scarring

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

9 Apr 2025

Protein linked to Parkinson's also found to drive melanoma growth

A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.

9 Apr 2025

Mental health disorders more prevalent in people with criminal legal histories

A new national epidemiological survey provides a demographic and diagnostic picture of people living with mental ill health in prison, those with criminal legal involvement in the last year, and those with no criminal legal history in the last year-finding significantly higher rates of five mental health conditions in incarcerated individuals and individuals with recent criminal legal history.

9 Apr 2025

Cannabis users have elevated dopamine levels associated with psychosis

A McGill University-led study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with psychosis.

9 Apr 2025

Genetic fusion drives unexpectedly fast growth in chronic myeloid leukemia

A new study has unveiled when chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

9 Apr 2025

Genetic breakthrough in psychiatry using long-read genomic sequencing

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

9 Apr 2025

New method uses sugar molecules to identify pancreatic cancer subtypes

Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.

9 Apr 2025

Tim-3 identified as promising therapeutic target for Alzheimer's disease

Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer's disease (AD), but its role in the brain was unknown until now.

9 Apr 2025

ETH Zurich researchers identify redundancies between the genes involved in DNA repair

Researchers aThe DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information.t ETH Zurich have unraveled the complex network that cells use to repair their genetic material.

9 Apr 2025

Menstrual cycle may drive inflammation in women with sickle cell disease

A marker linked to inflammation, C-reactive protein, may increase significantly during the follicular phase of the menstrual cycle in female patients with sickle cell disease (SCD), according to emerging research published today in Blood Vessels, Thrombosis & Hemostasis.

9 Apr 2025

Gum disease linked to worsening liver health

There is growing recognition in medicine that what happens in one part of the body can ripple through others.

9 Apr 2025

Increased allergy symptoms tied to changing climate patterns

A review published in The Laryngoscope indicates that climate change's effects on pollen seasons and concentrations are contributing to increasing rates of allergic rhinitis, or hay fever.

9 Apr 2025

Fish swim bladder hydrogel shows promise in heart repair

Hydrogels, which are soft materials formed by crosslinking polymers, could have a variety of medical applications.

9 Apr 2025

Laser-based infrared molecular fingerprinting detects common cancers

Cancer diagnoses traditionally require invasive or labor-intensive procedures such as tissue biopsies.

9 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected by the condition.

9 Apr 2025

Neural organoids offer insight into mechanisms of dementia

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids – also known as "mini-brain" models – from patients with frontotemporal lobar degeneration (FTLD).

9 Apr 2025