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Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

New drug compound prevents long COVID symptoms in mice

Researchers have shown a new drug compound can prevent long COVID symptoms in mice – a landmark finding that could lead to a future treatment for the debilitating condition.

8 Apr 2025

Lack of ceramides in blood vessels could lead to obesity-related heart diseases

New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes-not the presence of certain fats, but their suppression.

8 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Daytime eating could mitigate health risks of night shift work

A study led by researchers at Mass General Brigham suggests that, when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing.

8 Apr 2025

Global research initiative aims to optimize post-cardiac arrest ICU care

Researchers at 60 different intensive care units around the world are seeking to establish methods to expedite and improve post-cardiac arrest recovery at ICUs.

8 Apr 2025

Semaglutide linked to higher risk of vision problems, FDA data analysis shows

Researchers from the University of Bern analyzed over 300,000 FDA reports and found semaglutide use was linked to a higher reporting rate of vision impairment. The findings call for further study into the ocular risks of this widely prescribed diabetes and weight loss drug.

8 Apr 2025

AI boosts liver cancer detection by highlighting doubtful areas

A new editorial was published in Oncotarget, Volume 16, on April 4, 2025, titled "Deep learning-based uncertainty quantification for quality assurance in hepatobiliary imaging-based techniques."

8 Apr 2025

Genetic tendency to sedentary behavior linked to higher heart disease risk

Although sedentary behavior may be an evolutionarily selected trait, it is still important to try to be physically active, says a new study conducted at the University of Jyväskylä, Finland.

8 Apr 2025

Shingles vaccination associated with reduction in probability of new dementia diagnosis

Vaccination to prevent shingles also reduces the risk of developing dementia in later life, according to a research paper published recently in Nature.

8 Apr 2025

Study links gut microbe shifts in migrants to cardiovascular risk

An Amsterdam UMC-led study has found that migrants, this case from West Africa to Europe, experience a 'clear change' in their microbiome composition as compared to their non-migrant peers in West Africa, which expose them to an increase of cardiovascular disease.

8 Apr 2025

Proteins linked to Parkinson's and ALS found to protect mitochondria

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

New 3D imaging technique enhances basal cell carcinoma diagnosis

Researchers from the Agency for Science, Technology and Research (A*STAR) and the National Healthcare Group (NHG) have jointly pioneered an innovative imaging technique combining Multispectral Optoacoustic Tomography (MSOT) with artificial intelligence (AI) that could significantly improve the diagnosis and treatment of basal cell carcinoma (BCC), the most common form of skin cancer worldwide.

8 Apr 2025

How air pollution may be undermining your brain—one breath at a time

Research reveals air pollution, particularly from industry and fuels, negatively affects cognitive function in older adults, with language skills most impacted.

8 Apr 2025

Study reveals high rate of diagnostic changes in Parkinson’s disease

A new study by the University of Turku and Turku University Hospital, Finland, found that a significant proportion of Parkinson's disease diagnoses are later corrected.

7 Apr 2025

Faulty gene linked to increased risk of punctured lung in thousands

As many as one in 3,000 people could be carrying a faulty gene that significantly increases their risk of a punctured lung, according to new estimates from Cambridge researchers. Previous estimates had put this risk closer to one in 200,000 people.

7 Apr 2025

New quantum technology set to revolutionize gastrointestinal cancer detection and treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.

7 Apr 2025

$Diet and exercise habits in your 60s linked to lower fracture and heart death risk$

Diet and exercise habits in your 60s linked to lower fracture and heart death risk

A long-term study in older adults links higher-quality diets to lower risks of hip fracture and cardiovascular death. Researchers suggest that framing bone health through heart disease awareness may better engage men in preventive action.

7 Apr 2025

Study reveals socioeconomic inequalities in unmet needs for mental health care across the EU

A new study presented today at the European Psychiatric Association Congress 2025 reveals significant socioeconomic inequalities in unmet needs for mental health care across European Union countries, with financial barriers disproportionately affecting lower-income populations.

7 Apr 2025

Hospital addiction consultation service boosts treatment initiation for opioid use disorder

Specialized hospital services that aid people with opioid use disorder regardless of why they are admitted can boost the number of patients who begin treatment with FDA-approved medication for opioid use disorder and increase the likelihood they remain engaged in that care once discharged, according to a new study.

7 Apr 2025