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Beyond BRCA: Epigenetic Silencing in Breast Cancer

An interview with Professor William Newman, discussing his recent discovery in the field of breast cancer research, and the options that this will provide for women who have a family history of breast cancer but test negative for BRCA1/2 mutations.

8 Oct 2018

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

Lyra Therapeutics, Inc., a clinical-stage biotechnology company developing medicines precisely designed to target ear, nose and throat diseases, today announced the presentation of Phase 1 clinical data for the company's lead therapeutic, LYR-210, for chronic rhinosinusitis, a debilitating disease caused by inflammation of the paranasal sinus tissues that affects approximately 27 million people, or 11% of the adult population in the U.S.

8 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Researchers show possibility to restore insulin cell function in type 2 diabetes

By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease.

8 Oct 2018

DNA of people with depression, trauma is biologically older than healthy individuals

DNA from people who suffer from major depression is biologically older than that of healthy people by on average 8 months, suggesting that they are biologically older than their corresponding calendar age.

8 Oct 2018

FDA and EMA accept Novartis' regulatory application for siponimod to treat SPMS in adults

Novartis today announced that both the US Food and Drug Administration and European Medicines Agency have accepted the company's New Drug Application and Marketing Authorization Application respectively, for investigational oral, once-daily siponimod (BAF312) for the treatment of secondary progressive multiple sclerosis in adults.

8 Oct 2018

Immunotherapy effective for individuals with inherited form of skin cancer

Individuals with an inherited form of skin cancer often have a poor prognosis. The type of immunotherapy that was awarded this year's Nobel Prize in Physiology or Medicine is, however, particularly effective in this patient group, research from Karolinska Institutet in Sweden shows. The study is published in the Journal of Medical Genetics.

8 Oct 2018

Scientists discover new molecular pathway that controls colorectal cancer development

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a new molecular pathway that controls colorectal cancer development, and their exciting findings open new therapeutic opportunities.

8 Oct 2018

Postmenopausal women who lost weight had lower risk of developing invasive breast cancer

In a study of postmenopausal women, participants who lost weight had a lower risk of developing invasive breast cancer than those who maintained or gained weight. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that weight loss may help lower postmenopausal women's breast cancer risk.

8 Oct 2018

New blood test may detect early-stage lung cancer when surgical intervention is not possible

Non-small-cell lung carcinoma is often fatal because most cases are not diagnosed until they are so advanced that surgical intervention is no longer possible. To improve outcomes researchers are developing a blood test to detect lung cancer earlier in the disease.

8 Oct 2018

Study: Pregnant women with mental health history recognize babies' expressions differently

A pilot study has found that pregnant women who have suffered from depression or bipolar disorder (i.e. both mania and depression) recognize babies' faces and how babies laugh or cry, differently to healthy controls.

8 Oct 2018

Diet and weight may influence response to bipolar disorder treatment, shows study

Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to contribute to general inflammation.

8 Oct 2018

Nonfatal injuries in the U.S. cost over $1.8 trillion in 2013

A new analysis by researchers from Brown University and the Pacific Institute for Research and Evaluation has found that nonfatal injuries in the U.S. in the year 2013 cost more than $1.8 trillion.

8 Oct 2018

T-CALM Phase 2 clinical study results offer hope for essential tremor patients

Cavion, Inc., a leading clinical stage biotechnology company committed to developing novel therapeutics for people with neurological diseases, today announced promising results of the T-CALM Phase 2 clinical trial of its first-in-class T-type calcium channel modulator CX-8998 in essential tremor.

7 Oct 2018

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Leadiant Biosciences, Inc. today announced that the Food and Drug Administration has granted approval to Revcovi (elapegademase-lvlr) injection in the U.S. Revcovi is a new enzyme replacement therapy for the treatment of adenosine deaminase severe combined immune deficiency in pediatric and adult patients.

7 Oct 2018

Medical Condition News

Beyond BRCA: Epigenetic Silencing in Breast Cancer

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Researchers show possibility to restore insulin cell function in type 2 diabetes

DNA of people with depression, trauma is biologically older than healthy individuals

FDA and EMA accept Novartis' regulatory application for siponimod to treat SPMS in adults

Immunotherapy effective for individuals with inherited form of skin cancer

Scientists discover new molecular pathway that controls colorectal cancer development

Postmenopausal women who lost weight had lower risk of developing invasive breast cancer

New blood test may detect early-stage lung cancer when surgical intervention is not possible

Study: Pregnant women with mental health history recognize babies' expressions differently

Diet and weight may influence response to bipolar disorder treatment, shows study

Nonfatal injuries in the U.S. cost over $1.8 trillion in 2013

T-CALM Phase 2 clinical study results offer hope for essential tremor patients

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Online and in-person care found to be equally effective at improving psoriasis symptoms

Loyola launches research program to study new treatment for stroke, spinal cord injury

Dementia prevention trial participants are motivated by altruism, study suggests

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

Researchers develop cancer vaccine platform to improve efficacy of oncolytic enveloped viruses

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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