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Researchers investigate how nephrologists should discuss treatment options with older patients

Kidney specialists differ in their approaches to treatment decision-making with older patients with kidney failure, with many nephrologists not describing conservative management and some limiting patients' role in decision-making, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology

27 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Committee for Medicinal Products for Human Use has adopted a Positive Opinion recommending marketing authorization of patisiran for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

27 Jul 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018

Targeting mossy cells may offer new strategy for treating brain disorders

A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.

27 Jul 2018

Newer version of ALS drug may effectively treat inherited form of the disease

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1.

27 Jul 2018

Brain scan can help select the right Parkinson’s patients for clinical trials

From today forward, researchers and drug companies have a new tool in the search for better treatments for Parkinson’s – a brain scan that can be used to select the right people for clinical trials.

27 Jul 2018

DePuy Synthes introduces new CONCORDE LIFT Implant to treat patients with degenerative disc disease

Johnson & Johnson Medical Devices Companies today announced that DePuy Synthes is launching the CONCORDE LIFT Expandable Interbody Device in the U.S.

From DePuy Synthes 27 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

Qualification of first Parkinson's biomarker represents major milestone in clinical trials

The biomarker is used to determine the presence of dopamine transport deficiency in the brain, and has been qualified as an enrichment biomarker for clinical trials targeting early stages of Parkinson's, soon after diagnosis

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

Researchers develop nano-carriers to specifically target senescent cells

Senescent cells are damaged cells that do not perform their normal roles anymore but that are not dead -hence they are commonly known as zombi cells.

27 Jul 2018

Brain's response to taste stimuli could play role in driving anorexia nervosa

Researchers at the University of Colorado Anschutz Medical Campus have found that the brain's response to taste stimuli is linked to high anxiety and a drive for thinness that could play a role in driving anorexia nervosa.

27 Jul 2018

Scientists identify brain cells that help zebrafishes to socialize

University of Oregon scientists have identified brain cells vital to how zebrafish socialize. When the neurons are disabled, their orientation to one another breaks down in ways similar to socialization problems seen in humans with autism spectrum disorders and schizophrenia.

27 Jul 2018

Pilot study uses naturalistic driving approach to examine self-regulation behavior of older adults with AD

Driving is a complex task that involves perceptual, motor and cognitive abilities. These abilities may be affected in early Alzheimer Disease (AD) patients.

27 Jul 2018

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments.

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Using a fan to cool down can worsen allergies like hayfever

Britain is facing a heat wave this week with maximum temperatures hovering around 34C. This heat may make sleeping comfortably at night difficult. To combat the heat many people turn on their fans to cool down as they sleep. Mark Reddick, wrote for Sleep Advisor and explained how the use of the fans at night can have a negative impact on health.

27 Jul 2018

People with skin of color experience a variety of skin conditions

Although skin disease can affect anyone, it may not affect everyone in the same way - and this is especially true for patients with skin of color.

26 Jul 2018

Medical Condition News

Researchers investigate how nephrologists should discuss treatment options with older patients

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

Targeting mossy cells may offer new strategy for treating brain disorders

Newer version of ALS drug may effectively treat inherited form of the disease

Brain scan can help select the right Parkinson’s patients for clinical trials

DePuy Synthes introduces new CONCORDE LIFT Implant to treat patients with degenerative disc disease

Bile acids from the gut may offer new treatment for cocaine abuse

Qualification of first Parkinson's biomarker represents major milestone in clinical trials

Researchers discover new protein that controls level of inflammation-inducing molecule

Scientists take important step to understand mechanisms that cause Huntington's disease

Researchers develop nano-carriers to specifically target senescent cells

Brain's response to taste stimuli could play role in driving anorexia nervosa

Scientists identify brain cells that help zebrafishes to socialize

Pilot study uses naturalistic driving approach to examine self-regulation behavior of older adults with AD

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

Using a fan to cool down can worsen allergies like hayfever

People with skin of color experience a variety of skin conditions

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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